Search Results - "Crane, Christopher H."

Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results by Reyngold, Marsha, Parikh, Parag, Crane, Christopher H

“…Standard doses of conventionally fractionated radiation have had minimal to no impact on the survival duration of patients with locally advanced unresectable…”
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Hypofractionated ablative radiotherapy for locally advanced pancreatic cancer by Crane, Christopher H.

“…The role of radiation in locally advanced unresectable pancreatic cancer (LAPC) is controversial. Randomized trials evaluating standard doses of chemoradiation…”
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Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications by Churi, Chaitanya R, Shroff, Rachna, Wang, Ying, Rashid, Asif, Kang, HyunSeon C, Weatherly, Jacqueline, Zuo, Mingxin, Zinner, Ralph, Hong, David, Meric-Bernstam, Funda, Janku, Filip, Crane, Christopher H, Mishra, Lopa, Vauthey, Jean-Nicholas, Wolff, Robert A, Mills, Gordon, Javle, Milind

“…Cholangiocarcinoma (CCA) is clinically heterogeneous; intra and extrahepatic CCA have diverse clinical presentations. Next generation sequencing (NGS)…”
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Focal Radiation Therapy Dose Escalation Improves Overall Survival in Locally Advanced Pancreatic Cancer Patients Receiving Induction Chemotherapy and Consolidative Chemoradiation by Krishnan, Sunil, MD, Chadha, Awalpreet S., MD, Suh, Yelin, PhD, Chen, Hsiang-Chun, PhD, Rao, Arvind, PhD, Das, Prajnan, MD, Minsky, Bruce D., MD, Mahmood, Usama, MD, Delclos, Marc E., MD, Sawakuchi, Gabriel O., PhD, Beddar, Sam, PhD, Katz, Matthew H., MD, Fleming, Jason B., MD, Javle, Milind M., MD, Varadhachary, Gauri R., MD, Wolff, Robert A., MD, Crane, Christopher H., MD

“…Purpose To review outcomes of locally advanced pancreatic cancer (LAPC) patients treated with dose-escalated intensity modulated radiation therapy (IMRT) with…”
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Metastatic Pancreatic Cancer: ASCO Guideline Update by Sohal, Davendra P.S., Kennedy, Erin B., Cinar, Pelin, Conroy, Thierry, Copur, Mehmet S., Crane, Christopher H., Garrido-Laguna, Ignacio, Lau, Michelle W., Johnson, Tyler, Krishnamurthi, Smitha, Moravek, Cassadie, O’Reilly, Eileen M., Philip, Philip A., Pant, Shubham, Shah, Manish A., Sahai, Vaibhav, Uronis, Hope E., Zaidi, Neeha, Laheru, Daniel

“…PURPOSE The aim of this work was to provide an update to the ASCO guideline on metastatic pancreatic cancer pertaining to recommendations for therapy options…”
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Conventionally fractionated radiation therapy versus stereotactic body radiation therapy for locally advanced pancreatic cancer (CRiSP): An international systematic review and meta‐analysis by Tchelebi, Leila T., Lehrer, Eric J., Trifiletti, Daniel M., Sharma, Navesh K., Gusani, Niraj J., Crane, Christopher H., Zaorsky, Nicholas G.

“…Background The goal of this study was to characterize the efficacy and safety of stereotactic body radiation therapy (SBRT) versus conventionally fractionated…”
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Metastatic Pancreatic Cancer: ASCO Clinical Practice Guideline Update by Sohal, Davendra P S, Kennedy, Erin B, Khorana, Alok, Copur, Mehmet S, Crane, Christopher H, Garrido-Laguna, Ignacio, Krishnamurthi, Smitha, Moravek, Cassadie, O'Reilly, Eileen M, Philip, Philip A, Ramanathan, Ramesh K, Ruggiero, Joseph T, Shah, Manish A, Urba, Susan, Uronis, Hope E, Lau, Michelle W, Laheru, Daniel

“…Purpose In 2016, ASCO published a guideline to assist in clinical decision making in metastatic pancreatic cancer for initial assessment after diagnosis,…”
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Hilar Cholangiocarcinoma: expert consensus statement by Mansour, John C, Aloia, Thomas A, Crane, Christopher H, Heimbach, Julie K, Nagino, Masato, Vauthey, Jean-Nicolas

“…Abstract An American Hepato-Pancreato-Biliary Association (AHPBA)-sponsored consensus meeting of expert panellists met on 15 January 2014 to review current…”
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Locally Advanced, Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline by Balaban, Edward P, Mangu, Pamela B, Khorana, Alok A, Shah, Manish A, Mukherjee, Somnath, Crane, Christopher H, Javle, Milind M, Eads, Jennifer R, Allen, Peter, Ko, Andrew H, Engebretson, Anitra, Herman, Joseph M, Strickler, John H, Benson, 3rd, Al B, Urba, Susan, Yee, Nelson S

“…To provide evidence-based recommendations to oncologists and others for treatment of patients with locally advanced, unresectable pancreatic cancer. American…”
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Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline by Sohal, Davendra P S, Mangu, Pamela B, Khorana, Alok A, Shah, Manish A, Philip, Philip A, O'Reilly, Eileen M, Uronis, Hope E, Ramanathan, Ramesh K, Crane, Christopher H, Engebretson, Anitra, Ruggiero, Joseph T, Copur, Mehmet S, Lau, Michelle, Urba, Susan, Laheru, Daniel

“…To provide evidence-based recommendations to oncologists and others for the treatment of patients with metastatic pancreatic cancer. American Society of…”
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Gemcitabine Alone Versus Gemcitabine Plus Radiotherapy in Patients With Locally Advanced Pancreatic Cancer: An Eastern Cooperative Oncology Group Trial by LOEHRER, Patrick J, YANG FENG, BENSON, Al B, CARDENES, Higinia, WAGNER, Lynne, BRELL, Joanna M, CELLA, David, FLYNN, Patrick, RAMANATHAN, Ramesh K, CRANE, Christopher H, ALBERTS, Steven R

“…The purpose of this trial was to evaluate the role of radiation therapy with concurrent gemcitabine (GEM) compared with GEM alone in patients with localized…”
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Neoadjuvant Treatment Response As an Early Response Indicator for Patients With Rectal Cancer by Park, In Ja, You, Y Nancy, Agarwal, Atin, Skibber, John M, Rodriguez-Bigas, Miguel A, Eng, Cathy, Feig, Barry W, Das, Prajnan, Krishnan, Sunil, Crane, Christopher H, Hu, Chung-Yuan, Chang, George J

“…Neoadjuvant chemoradiotherapy for rectal cancer is associated with improved local control and may result in complete tumor response. Associations between tumor…”
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Phase II Trial of Cetuximab, Gemcitabine, and Oxaliplatin Followed by Chemoradiation With Cetuximab for Locally Advanced (T4) Pancreatic Adenocarcinoma: Correlation of Smad4(Dpc4) Immunostaining With Pattern of Disease Progression by CRANE, Christopher H, VARADHACHARY, Gauri R, DAS, Prajnan, LEE, Jeffrey E, ABBRUZZESE, James L, WOLFF, Robert A, YORDY, John S, STAERKEL, Gregg A, JAVLE, Milind M, SAFRAN, Howard, HAQUE, Waqar, HOBBS, Bridgett D, KRISHNAN, Sunil, FLEMING, Jason B

“…This phase II trial was designed to assess the efficacy and safety of cetuximab, gemcitabine, and oxaliplatin followed by cetuximab, capecitabine, and…”
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Preoperative Gemcitabine-Based Chemoradiation for Patients With Resectable Adenocarcinoma of the Pancreatic Head by EVANS, Douglas B, VARADHACHARY, Gauri R, CHARNSANGAVEJ, Chusilp, LANO, Elizabeth A, HO, Linus, LENZI, Renato, ABBRUZZESE, James L, WOLFF, Robert A, CRANE, Christopher H, SUN, Charlotte C, LEE, Jeffrey E, PISTERS, Peter W. T, VAUTHEY, Jean-Nicolas, HUAMIN WANG, CLEARY, Karen R, STAERKEL, Gregg A

“…We conducted a phase II trial to assess the outcomes of patients who received preoperative gemcitabine-based chemoradiation and pancreaticoduodenectomy (PD)…”
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Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience by Cloyd, Jordan M., Katz, Matthew H. G., Prakash, Laura, Varadhachary, Gauri R., Wolff, Robert A., Shroff, Rachna T., Javle, Milind, Fogelman, David, Overman, Michael, Crane, Christopher H., Koay, Eugene J., Das, Prajnan, Krishnan, Sunil, Minsky, Bruce D., Lee, Jeffrey H., Bhutani, Manoop S., Weston, Brian, Ross, William, Bhosale, Priya, Tamm, Eric P., Wang, Huamin, Maitra, Anirban, Kim, Michael P., Aloia, Thomas A., Vauthey, Jean-Nicholas, Fleming, Jason B., Abbruzzese, James L., Pisters, Peter W. T., Evans, Douglas B., Lee, Jeffrey E.

“…Background The purpose of this study was to evaluate a single-institution experience with delivery of preoperative therapy to patients with pancreatic ductal…”
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Duodenal Toxicity After Fractionated Chemoradiation for Unresectable Pancreatic Cancer by Kelly, Patrick, MD, PhD, Das, Prajnan, MD, MS, MPH, Pinnix, Chelsea C., MD, PhD, Beddar, Sam, PhD, Briere, Tina, PhD, Pham, Mary, BS, Krishnan, Sunil, MD, Delclos, Marc E., MD, Crane, Christopher H., MD

“…Purpose Improving local control is critical to improving survival and quality of life for patients with locally advanced unresectable pancreatic cancer (LAPC)…”
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Treatment Sequencing for Resectable Pancreatic Cancer: Influence of Early Metastases and Surgical Complications on Multimodality Therapy Completion and Survival by Tzeng, Ching-Wei D., Cao, Hop S. Tran, Lee, Jeffrey E., Pisters, Peter W. T., Varadhachary, Gauri R., Wolff, Robert A., Abbruzzese, James L., Crane, Christopher H., Evans, Douglas B., Wang, Huamin, Abbott, Daniel E., Vauthey, Jean-Nicolas, Aloia, Thomas A., Fleming, Jason B., Katz, Matthew H. G.

“…Barriers to multimodality therapy (MMT) completion among patients with resectable pancreatic adenocarcinoma include early cancer progression and postoperative…”
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Borderline Resectable Pancreatic Cancer: The Importance of This Emerging Stage of Disease by Katz, Matthew H.G., MD, Pisters, Peter W.T., MD, FACS, Evans, Douglas B., MD, FACS, Sun, Charlotte C., DrPH, MPH, Lee, Jeffrey E., MD, FACS, Fleming, Jason B., MD, FACS, Vauthey, J. Nicolas, MD, FACS, Abdalla, Eddie K., MD, FACS, Crane, Christopher H., MD, Wolff, Robert A., MD, Varadhachary, Gauri R., MD, Hwang, Rosa F., MD

“…Background Patients with borderline resectable pancreatic adenocarcinoma (PA) include those with localized disease who have tumor or patient characteristics…”
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Adjuvant chemotherapy in rectal cancer: Defining subgroups who may benefit after neoadjuvant chemoradiation and resection: A pooled analysis of 3,313 patients by Maas, Monique, Nelemans, Patty J, Valentini, Vincenzo, Crane, Christopher H., Capirci, Carlo, Rödel, Claus, Nash, Garrett M., Kuo, Li‐Jen, Glynne‐Jones, Rob, García‐Aguilar, Julio, Suárez, Javier, Calvo, Felipe A., Pucciarelli, Salvatore, Biondo, Sebastiano, Theodoropoulos, George, Lambregts, Doenja M.J., Beets‐Tan, Regina G.H., Beets, Geerard L.

“…Recent literature suggests that the benefit of adjuvant chemotherapy (aCT) for rectal cancer patients might depend on the response to neoadjuvant…”
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Transport properties of pancreatic cancer describe gemcitabine delivery and response by Koay, Eugene J, Truty, Mark J, Cristini, Vittorio, Thomas, Ryan M, Chen, Rong, Chatterjee, Deyali, Kang, Ya'an, Bhosale, Priya R, Tamm, Eric P, Crane, Christopher H, Javle, Milind, Katz, Matthew H, Gottumukkala, Vijaya N, Rozner, Marc A, Shen, Haifa, Lee, Jeffery E, Wang, Huamin, Chen, Yuling, Plunkett, William, Abbruzzese, James L, Wolff, Robert A, Varadhachary, Gauri R, Ferrari, Mauro, Fleming, Jason B

“…The therapeutic resistance of pancreatic ductal adenocarcinoma (PDAC) is partly ascribed to ineffective delivery of chemotherapy to cancer cells. We…”
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