Search Results - "Crane, Christine M"

Synthesis and Evaluation of Selected Key Methyl Ether Derivatives of Vancomycin Aglycon by Crane, Christine M, Pierce, Joshua G, Leung, Siegfried S. F, Tirado-Rives, Julian, Jorgensen, William L, Boger, Dale L

“…A select series of methyl ether derivatives of vancomcyin aglycon were prepared and examined for antimicrobial activity against vancomycin-sensitive…”
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Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis by Crane, Christine M., Hirsch, Anna K. H., Alphey, Magnus S., Sgraja, Tanja, Lauw, Susan, Illarionova, Victoria, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

“…The enzymes of the non‐mevalonate pathway for isoprenoid biosynthesis are attractive targets for the development of novel drugs against malaria and…”
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Synthesis and Evaluation of Vancomycin Aglycon Analogues That Bear Modifications in the N-Terminal d-Leucyl Amino Acid by Crane, Christine M, Boger, Dale L

“…The synthesis and biological evaluation of a series of vancomycin aglycon analogues bearing alternative residue 1 N-methyl-d-amino acids are described. The…”
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Total Synthesis of [Ψ[C(S)NH]Tpg4]Vancomycin Aglycon, [Ψ[C(NH)NH]Tpg4]Vancomycin Aglycon, and Related Key Compounds: Reengineering Vancomycin for Dual d-Ala-d-Ala and d-Ala-d-Lac Binding by Xie, Jian, Okano, Akinori, Pierce, Joshua G, James, Robert C, Stamm, Simon, Crane, Christine M, Boger, Dale L

“…The total synthesis of [Ψ[C(S)NH]Tpg4]vancomycin aglycon (8) and its unique AgOAc-promoted single-step conversion to [Ψ[C(NH)NH]Tpg4]vancomycin aglycon (7),…”
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Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy by Crane, Christine M., Kaiser, Johannes, Ramsden, Nicola L., Lauw, Susan, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

“…Designed inhibitors (like 1) of IspF, a key enzyme in the non‐mevalonate pathway for terpene biosynthesis and a potential antimalarial target, were synthesized…”
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N-Phenylphenylglycines as Novel Corticotropin Releasing Factor Receptor Antagonists by Molteni, Valentina, Penzotti, Julie, Wilson, Dean M, Termin, Andreas P, Mao, Long, Crane, Christine M, Hassman, Fred, Wang, Tao, Wong, Harvey, Miller, Keith J, Grossman, Scott, Grootenhuis, Peter D. J

“…Screening of a computationally designed synthetic library led to the discovery of the N-phenylphenylglycines (NPPGs) as a novel class of human corticotropin…”
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Total Synthesis of [Ψ[C(═S)NH]Tpg 4 ]Vancomycin Aglycon, [Ψ[C(═NH)NH]Tpg 4 ]Vancomycin Aglycon, and Related Key Compounds: Reengineering Vancomycin for Dual d -Ala- d -Ala and d -Ala- d -Lac Binding by Xie, Jian, Okano, Akinori, Pierce, Joshua G., James, Robert C., Stamm, Simon, Crane, Christine M., Boger, Dale L.

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Fluoreszierende Inhibitoren von IspF, einem Enzym im “Nicht‐Mevalonat‐Biosyntheseweg” der Isoprenoide und möglichen Ziel einer Antimalariatherapie by Crane, Christine M., Kaiser, Johannes, Ramsden, Nicola L., Lauw, Susan, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

“…Strukturbasiert entworfene Hemmstoffe (wie 1) von IspF, einem Schlüsselenzym im „Nicht‐Mevalonat‐Weg“ der Terpenbiosynthese, wurden synthetisiert und auf ihre…”
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Fluoreszierende Inhibitoren von IspF, einem Enzym im "Nicht-Mevalonat-Biosyntheseweg" der Isoprenoide und möglichen Ziel einer Antimalariatherapie by Crane, Christine M., Kaiser, Johannes, Ramsden, Nicola L., Lauw, Susan, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

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