Search Results - "Cramer, Megan L."

Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes by Cramer, Megan L., Xu, Rui, Martin, Paul T.

“…GALGT2 (also B4GALNT2) encodes a glycosyltransferase that is normally confined to the neuromuscular and myotendinous junction in adult skeletal muscle. GALGT2…”
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Fibrogenesis in LAMA2 -Related Muscular Dystrophy Is a Central Tenet of Disease Etiology by Accorsi, Anthony, Cramer, Megan L, Girgenrath, Mahasweta

“…-related congenital muscular dystrophy, also known as MDC1A, is caused by loss-of-function mutations in the alpha2 chain of Laminin-211. Loss of this protein…”
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Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans by Zygmunt, Deborah A., Singhal, Neha, Kim, Mi-Lyang, Cramer, Megan L., Crowe, Kelly E., Xu, Rui, Jia, Ying, Adair, Jessica, Martinez-Pena y Valenzuela, Isabel, Akaaboune, Mohammed, White, Peter, Janssen, Paulus M., Martin, Paul T.

“…Sarcopenia, the loss of muscle mass and strength during normal aging, involves coordinate changes in skeletal myofibers and the cells that contact them,…”
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An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque by Xu, Rui, Jia, Ying, Zygmunt, Deborah A., Cramer, Megan L., Crowe, Kelly E., Shao, Guohong, Maki, Agatha E., Guggenheim, Haley N., Hood, Benjamin C., Griffin, Danielle A., Peterson, Ellyn, Bolon, Brad, Cheatham, John P., Cheatham, Sharon L., Flanigan, Kevin M., Rodino-Klapac, Louise R., Chicoine, Louis G., Martin, Paul T.

“…Recombinant adeno-associated virus (rAAV)rh74.MCK.GALGT2 is a muscle-specific gene therapy that is being developed to treat forms of muscular dystrophy. Here…”
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Induction of T-Cell Infiltration and Programmed Death Ligand 2 Expression by Adeno-Associated Virus in Rhesus Macaque Skeletal Muscle and Modulation by Prednisone by Cramer, Megan L, Shao, Guohong, Rodino-Klapac, Louise R, Chicoine, Louis G, Martin, Paul T

“…Use of adeno-associated virus (AAV) to transduce genes into skeletal muscles can be associated with T-cell responses to viral capsid and/or to transgenic…”
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An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK. GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque by Xu, Rui, Jia, Ying, Zygmunt, Deborah A, Cramer, Megan L, Crowe, Kelly E, Shao, Guohong, Maki, Agatha E, Guggenheim, Haley N, Hood, Benjamin C, Griffin, Danielle A, Peterson, Ellyn, Bolon, Brad, Cheatham, John P, Cheatham, Sharon L, Flanigan, Kevin M, Rodino-Klapac, Louise R, Chicoine, Louis G, Martin, Paul T

“…Recombinant adeno-associated virus (rAAV)rh74.MCK. is a muscle-specific gene therapy that is being developed to treat forms of muscular dystrophy. Here we…”
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