Search Results - "Cramer, Julie M"

Distinct human stem cell populations in small and large intestine by Cramer, Julie M, Thompson, Timothy, Geskin, Albert, LaFramboise, William, Lagasse, Eric

“…The intestine is composed of an epithelial layer containing rapidly proliferating cells that mature into two regions, the small and the large intestine…”
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Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation by Wang, Xinwei, Wei, Liang, Cramer, Julie M., Leibowitz, Brian J., Judge, Colleen, Epperly, Michael, Greenberger, Joel, Wang, Fengchao, Li, Linheng, Stelzner, Matthias G., Dunn, James C. Y., Martin, Martin G., Lagasse, Eric, Zhang, Lin, Yu, Jian

“…Exposure to high levels of ionizing radiation (IR) leads to debilitating and dose-limiting gastrointestinal (GI) toxicity. Using three-dimensional mouse crypt…”
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Deletion of Ptp4a3 reduces clonogenicity and tumor-initiation ability of colitis-associated cancer cells in mice by Cramer, Julie M., Zimmerman, Mark W., Thompson, Tim, Homanics, Gregg E., Lazo, John S., Lagasse, Eric

“…The PTP4A3 gene is highly expressed in human colon cancer and often associates with enhanced metastatic potential. Genetic disruption of the mouse Ptp4a3 gene…”
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