Search Results - "Cramer, Jonathan"

Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN by Cramer, Jonathan

“…In their role as pattern-recognition receptors on cells of the innate immune system, myeloid C-type lectin receptors (CLRs) assume important biological…”
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Hydroxyl Groups in Synthetic and Natural-Product-Derived Therapeutics: A Perspective on a Common Functional Group by Cramer, Jonathan, Sager, Christoph P, Ernst, Beat

“…By forming extended hydrogen-bond networks, the contribution of hydroxyl groups to affinity can reach several orders of magnitude. However, because of the high…”
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Echocardiographic Diagnosis, Surgical Treatment, and Outcomes of Anomalous Left Coronary Artery from the Pulmonary Artery by Patel, Shivani G., Frommelt, Michele A., Frommelt, Peter C., Kutty, Shelby, Cramer, Jonathan W.

“…Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare condition that can be difficult to diagnose by echocardiography alone. The purpose…”
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Clinical and Echocardiographic Prevalence and Detection of Congenital and Acquired Cardiac Abnormalities in Girls and Women with the Turner Syndrome by Yetman, Anji T., Starr, Lois, Sanmann, Jennifer, Wilde, Megan, Murray, Mary, Cramer, Jonathan W.

“…The prevalence of congenital and acquired heart disease in patients with the Turner syndrome (TS) is based on historic cohorts who underwent imaging before the…”
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The role of glycosylation patterns of viral glycoproteins and cell entry receptors in arenavirus infection by Gorzkiewicz, Michal, Cramer, Jonathan, Xu, Haifeng C., Lang, Philipp A.

“…Mammarenaviruses are enveloped RNA viruses that can be associated with rodent-transmitted diseases in humans. Their virions are composed of a nucleocapsid…”
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Assessment of Hypertension, Guideline-Directed Counseling, and Outcomes in the ACHD Population by Jepson, Amanda, Danford, David, Cramer, Jonathan W., Tsai, Shane, Yetman, Anji T.

“…Guidelines for the diagnosis and treatment of hypertension were published by the American Heart Association (AHA) in 2017. The prevalence of hypertension in…”
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Clinical Outcomes of Adult Fontan-Associated Liver Disease and Combined Heart-Liver Transplantation by Lewis, Matthew J., Reardon, Leigh C., Aboulhosn, Jamil, Haeffele, Christiane, Chen, Sharon, Kim, Yuli, Fuller, Stephanie, Forbess, Lisa, Alshawabkeh, Laith, Urey, Marcus A., Book, Wendy M., Rodriguez, Fred, Menachem, Jonathan N., Clark, Daniel E., Valente, Anne Marie, Carazo, Matthew, Egbe, Alexander, Connolly, Heidi M., Krieger, Eric V., Angiulo, Jilian, Cedars, Ari, Ko, Jong, Jacobsen, Roni M., Earing, Michael G., Cramer, Jonathan W., Ermis, Peter, Broda, Christopher, Nugaeva, Natalia, Ross, Heather, Awerbach, Jordan D., Krasuski, Richard A., Rosenbaum, Marlon

“…The impact of Fontan-associated liver disease (FALD) on post-transplant mortality and indications for combined heart-liver transplant (CHLT) in adult Fontan…”
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Increased Hepatic Stiffness in Young Adults After Biventricular Repair of Congenital Heart Disease by Zhang, Jin, Li, Ling, Jani, Vivek, Cramer, Jonathan W., Fletcher, Scott E., Cedars, Ari M., Danford, David A., Kutty, Shelby, Kutty, Shaija S.

“…This study evaluated hepatic stiffness by shear wave elastography to investigate subclinical hepatic changes in a cohort of patients with congenital…”
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Morbidity and Mortality in Adult Fontan Patients After Heart or Combined Heart-Liver Transplantation by Lewis, Matthew J., Reardon, Leigh C., Aboulhosn, Jamil, Haeffele, Christiane, Chen, Sharon, Kim, Yuli, Fuller, Stephanie, Forbess, Lisa, Alshawabkeh, Laith, Urey, Marcus A., Book, Wendy M., Rodriguez, Fred, Menachem, Jonathan N., Clark, Daniel E., Valente, Anne Marie, Carazo, Matthew, Egbe, Alexander, Connolly, Heidi M., Krieger, Eric V., Angiulo, Jilian, Cedars, Ari, Ko, Jong, Jacobsen, Roni M., Earing, Michael G., Cramer, Jonathan W., Ermis, Peter, Broda, Christopher, Nugaeva, Natalia, Ross, Heather, Awerbach, Jordan D., Krasuski, Richard A., Rosenbaum, Marlon

“…An increasing number of adult Fontan patients require heart transplantation (HT) or combined heart-liver transplant (CHLT); however, data regarding outcomes…”
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Tricuspid Repair at Pulmonary Valve Replacement Does Not Alter Outcomes in Tetralogy of Fallot by Cramer, Jonathan W., MD, Ginde, Salil, MD, Hill, Garick D., MD, Cohen, Scott B., MD, Bartz, Peter J., MD, Tweddell, James S., MD, Earing, Michael G., MD

“…Background Chronic pulmonary regurgitation after tetralogy of Fallot repair often leads to progressive right ventricle dilation, dysfunction, and frequently,…”
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The Spectrum of Congenital Heart Disease and Outcomes After Surgical Repair Among Children With Turner Syndrome: A Single-Center Review by Cramer, Jonathan W., Bartz, Peter J., Simpson, Pippa M., Zangwill, Steven D.

“…Turner syndrome (TS), a genetic abnormality affecting 1 in 2,500 people, is commonly associated with congenital heart disease (CHD). However, the surgical…”
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SPECTRUM OF CONGENITAL HEART DISEASE AND OUTCOMES IN CHILDREN WITH TURNER SYNDROME: A SINGLE-CENTER EXPERIENCE by Cramer, Jonathan W, Simpson, Pippa, Bartz, Peter, Zangwill, Steven

“…[...]the combination of TS and HLHS remains a very challenging population with generally poor survival…”
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Aortic Aneurysms Remain a Significant Source of Morbidity and Mortality After Use of Dacron® Patch Aortoplasty to Repair Coarctation of the Aorta: Results from a Single Center by Cramer, Jonathan W., Ginde, Salil, Bartz, Peter J., Tweddell, James S., Litwin, S. Bert, Earing, Michael G.

“…Aortic aneurysm formation after coarctation repair is a serious and life-threatening complication. Repairs using synthetic materials such as Dacron ® may carry…”
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Transition readiness in congenital heart disease: Are teens and young adults getting the recommended information? by Harrison, David J., Uzark, Karen, Gauvreau, Kimberlee, Yu, Sunkyung, Lowery, Ray, Yetman, Anji T., Cramer, Jonathan, Rudd, Nancy, Cohen, Scott, Gurvitz, Michelle

“…The 2011 American Heart Association best practices statement on transition for young adults with congenital heart disease (CHD) addresses both medical transfer…”
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Takeuchi repair of anomalous left coronary artery from the pulmonary artery by Cramer, Jonathan W., MD, Cinquegrani, Michael, MD, Cohen, Scott B., MD

“…Abstract Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare form of congenital heart disease that has been successfully palliated for…”
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Synthesis and Binding Mode Predictions of Novel Siglec‑7 Ligands by Frank, Martin, Kuhfeldt, Elena, Cramer, Jonathan, Watzl, Carsten, Prescher, Horst

“…Siglec-7 regulates immune cell activity and is a promising target for immunomodulation. Here, we report the discovery of novel sialic acid derivatives binding…”
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CONGENITAL CATASTROPHE- A DANGEROUS BLEED WITH A UNIQUE REPAIR by Gagnon, Kali, Hudgins, Hogan K., Delaney, Jeffrey W., Curzon, Christopher, Cramer, Jonathan W.

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Combating DC‐SIGN‐mediated SARS‐CoV‐2 dissemination by glycan‐mimicking polymers by Cramer, Jonathan, Jiang, Xiaohua, Aliu, Butrint, Ernst, Beat

“…Many viruses exploit the human C‐type lectin receptor dendritic cell‐specific ICAM‐3 grabbing nonintegrin (DC‐SIGN) for cell entry and virus dissemination. An…”
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OUTCOME OF PATIENTS WITH TURNER SYNDROME LIVING IN A RURAL VERSUS URBAN SETTING by Yetman, Angela T., Katz, Renee, Cramer, Jonathan

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Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands by Krimmer, Stefan G, Cramer, Jonathan, Betz, Michael, Fridh, Veronica, Karlsson, Robert, Heine, Andreas, Klebe, Gerhard

“…A previously studied congeneric series of thermolysin inhibitors addressing the solvent-accessible S2′ pocket with different hydrophobic substituents showed…”
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