Search Results - "Cramer, J W"
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Spectacular Hubble Space Telescope Observations of the Coma Galaxy D100 and Star Formation in Its Ram Pressure-stripped Tail
Published in The Astrophysical journal (10-01-2019)“…We present new HST F275W, F475W, and F814W imaging of the region of the Coma cluster around D100, a spiral galaxy with a remarkably long and narrow (60 × 1.5…”
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ALMA Evidence for Ram Pressure Compression and Stripping of Molecular Gas in the Virgo Cluster Galaxy NGC 4402
Published in The Astrophysical journal (01-10-2020)“…Abstract High-resolution (1″ × 2″) Atacama Large Millimeter Array CO(2−1) observations of the ram pressure stripped galaxy NGC 4402 in the Virgo cluster show…”
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Resolved UV and Optical Color Gradients Reveal Environmental Influence on Galaxy Evolution at Redshift z ∼ 1.6
Published in The Astrophysical journal (01-11-2024)“…Abstract The changes in colors across a galaxy are intimately connected to the galaxy’s formation, growth, quenching history, and dust content. A particularly…”
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A Large-scale Kinematic Study of Molecular Gas in High-z Cluster Galaxies: Evidence for High Levels of Kinematic Asymmetry
Published in The Astrophysical journal (01-02-2023)“…Abstract We investigate the resolved kinematics of the molecular gas, as traced by the Atacama Large Millimeter/submillimeter Array in CO (2−1), of 25 cluster…”
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Molecular Gas Filaments and Fallback in the Ram Pressure Stripped Coma Spiral NGC 4921
Published in The Astrophysical journal (01-11-2021)“…Abstract We investigate the effects of ram pressure on the molecular interstellar medium (ISM) in the disk of the Coma cluster galaxy NGC 4921 via…”
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Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABA A receptors: Improved bioavailability enhances anticonvulsant efficacy
Published in Neuropharmacology (15-07-2018)“…HZ-166 has previously been characterized as an α2,3-selective GABA receptor modulator with anticonvulsant, anxiolytic, and anti-nociceptive properties but…”
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Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats
Published in Drug metabolism and disposition (01-08-2016)“…The Zucker diabetic fatty (ZDF) rat, an inbred strain of obese Zucker fatty rat, develops early onset of insulin resistance and displays hyperglycemia and…”
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PRECLINICAL CHARACTERIZATION OF 2-[3-[3-[(5-ETHYL-4â²-FLUORO-2-HYDROXY[1,1â²-BIPHENYL]-4-YL)OXY]PROPOXY]-2-PROPYLPHENOXY]BENZOIC ACID METABOLISM: IN VITRO SPECIES COMPARISON AND IN VIVO DISPOSITION IN RATS
Published in Drug metabolism and disposition (01-11-2003)“…Assessment of the pharmacokinetics of [ 14 C]2-[3-[3-[(5-ethyl-4â²-fluoro-2-hydroxy[1,1â²-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy-]benzoic acid ([ 14…”
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Disposition of LY333531, a selective protein kinase C β inhibitor, in the Fischer 344 rat and beagle dog
Published in Xenobiotica (01-11-2002)“…1. Studies were conducted in the Fischer 344 rat and beagle dog to determine the disposition of LY333531 and its equipotent active des-methyl metabolite,…”
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In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life
Published in The Journal of neuroscience (01-10-2003)“…Soluble amyloid-beta (Abeta) peptide converts to structures with high beta-sheet content in Alzheimer's disease (AD). Soluble Abeta is released by neurons into…”
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A large-scale kinematic study of molecular gas in high-z cluster galaxies: Evidence for high levels of kinematic asymmetry
Published 14-09-2022“…We investigate the resolved kinematics of the molecular gas, as traced by ALMA in CO (2-1), of 25 cluster member galaxies across three different clusters at a…”
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A novel, a‐2, 3‐selective GABA A receptor modulator with improved central penetrability and associated antiepileptic and anti‐pain efficacy
Published in The FASEB journal (01-04-2016)“…Abstract only Background Positiveallosteric modulators of GABA A receptors transduce a host ofbeneficial effects but can have motor and sedative liabilities. A…”
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Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: Improved bioavailability enhances anticonvulsant efficacy
Published in Neuropharmacology (15-07-2018)“…HZ-166 has previously been characterized as an α2,3-selective GABAA receptor modulator with anticonvulsant, anxiolytic, and anti-nociceptive properties but…”
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N-Hydroxylation: A new metabolic reaction observed in the rat with the carcinogen 2-acetylaminofluorene
Published in The Journal of biological chemistry (01-03-1960)Get full text
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DNA synthesis by mammalian cells inhibited in culture by 5-lodo-2'-deoxyuridine
Published in Molecular pharmacology (01-01-1966)Get more information
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A simple method for concentration of cells in the DNA synthetic period of the mitotic cycle
Published in Experimental cell research (01-10-1967)Get more information
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5-iodo-2'-deoxyuridine and DNA synthesis in mammalian cells
Published in Experimental cell research (01-01-1968)Get more information
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Growth hormone and vitamin D in relation to growth and calcification on a calcium deficient diet
Published in Endocrinology (Philadelphia) (01-11-1957)Get more information
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Vitamin D and urinary amino acid excretion in the rat
Published in Proceedings of the Society for Experimental Biology and Medicine (01-10-1961)Get more information
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Solvability of nonlinear operator equations
Published in Pacific journal of mathematics (1981)Get full text
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