Search Results - "Crain, Jonathan"

Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma by Liu, Hao, Naxerova, Kamila, Pinter, Matthias, Incio, Joao, Lee, Hang, Shigeta, Kohei, Ho, William W, Crain, Jonathan A, Jacobson, Alex, Michelakos, Theodoros, Dias-Santos, Daniella, Zanconato, Andrea, Hong, Theodore S, Clark, Jeffrey W, Murphy, Janet E, Ryan, David P, Deshpande, Vikram, Lillemoe, Keith D, Fernandez-Del Castillo, Carlos, Downes, Michael, Evans, Ronald M, Michaelson, James, Ferrone, Cristina R, Boucher, Yves, Jain, Rakesh K

“…Angiotensin system inhibitors (ASI) can improve prognosis in multiple cancer types, including pancreatic ductal adenocarcinoma (PDAC). However, no study has…”
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Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway by Kweon, Hyae Yon, Lee, Mi-Ni, Dorfel, Max, Seo, Seungwoon, Gottlieb, Leah, PaPazyan, Thomas, McTiernan, Nina, Ree, Rasmus, Bolton, David, Garcia, Andrew, Flory, Michael, Crain, Jonathan, Sebold, Alison, Lyons, Scott, Ismail, Ahmed, Marchi, Elaine, Sonn, Seong-keun, Jeong, Se-Jin, Jeon, Sejin, Ju, Shinyeong, Conway, Simon J, Kim, Taesoo, Kim, Hyun-Seok, Lee, Cheolju, Roh, Tae-Young, Arnesen, Thomas, Marmorstein, Ronen, Oh, Goo Taeg, Lyon, Gholson J

“…Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major…”
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A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding by Avery, Adam W., Crain, Jonathan, Thomas, David D., Hays, Thomas S.

“…Spinocerebellar ataxia type 5 (SCA5) is a human neurodegenerative disease that stems from mutations in the SPTBN2 gene encoding the protein β-III-spectrin…”
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Probing Allosteric Mechanisms of Utrophin and Dystrophin Actin-Binding Domains, using Thermal Denaturation by Fealey, Michael E., Crain, Jonathan, Hinderliter, Anne, Thomas, David D.

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Proteomic and genomic characterization of a yeast model for Ogden syndrome by Dörfel, Max J., Fang, Han, Crain, Jonathan, Klingener, Michael, Weiser, Jake, Lyon, Gholson J.

“…Naa10 is an Nα‐terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co‐translationally acetylates the α‐amino group of newly…”
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Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts by Liu, Hao, Ho, William W., Naxerova, Kamila, Grahovac, Jelena, Nia, Hadi, Chen, Ivy, Posada, Jessica M., Schanne, Daniel H., Pinter, Matthias, Crain, Jonathan, Qi, Xialong, Clark, Jeffrey W., Hong, Theodore S., Ryan, David P., Huang, Peigen, Lillemoe, Keith D., Castillo, Carlos Fernández-Del, Ferrone, Cristina R, Downes, Michael, Evans, Ronald M., Deshpande, Vikram, Boucher, Yves, Jain, Rakesh K.

“…Abstract The resistance to therapy in pancreatic ductal adenocarcinoma (PDAC) is due in part to carcinoma-associated fibroblasts (CAFs) that produce a highly…”
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Abstract 957: Use of angiotensin system inhibitors is associated with longer overall survival in pancreatic ductal adenocarcinoma patients who underwent pancreatectomy by Liu, Hao, Pinter, Matthias, Incio, Joao, Lee, Hang, Ho, William, Crain, Jonathan, Naxerova, Kamila, Di, Mengyang, Jacobson, Alex, Santos, Daniella Dias, Zanconato, Andrea, Deshpande, Vikram, Lillemoe, Keith, Castillos, Carlos Fernandez del, Downes, Michael, Evans, Ronald, Michaelson, James, Ferrone, Cristina, Boucher, Yves, Rakesh, Jain K.

“…Abstract Introduction: Angiotensin system inhibitors (ASI) are widely used to manage hypertension. Laboratory and retrospective clinical data suggests that…”
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Use of Angiotensin System Inhibitors is Associated with Immune Activation and Longer Survival in Non-Metastatic Pancreatic Ductal Adenocarcinoma by Liu, Hao, Naxerova, Kamila, Pinter, Matthias, Incio, Joao, Lee, Hang, Shigeta, Kohei, Ho, William, Crain, Jonathan, Jacobson, Alex, Michelakos, Theodoros, Dias-Santos, Daniella, Zanconato, Andrea, Hong, Theodore S, Clark, Jeffrey W, Murphy, Janet E, Ryan, David P, Deshpande, Vikram, Lillemoe, Keith D, Castillo, Carlos Fernandez-del, Downes, Michael, Evans, Ronald M, Michaelson, James, Ferrone, Cristina R, Boucher, Yves, Jain, Rakesh K.

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Effects of Disease Causing Point Mutations on Actin's Resilience by Brate, Ashley, Lin, Ava, Crain, Jonathan, Prochniewicz, Ewa, Ervasti, Jamex, Thomas, David D.

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Large Scale Opening of the N Terminal Actin-Binding Domain of Dystrophin Detected by Dipolar Electron-Electron Resonance (DEER) by Crain, Jonathan, Lin, Ava Y., One Feather, Brandon, Brate, Ashley, Matthews, Gage, Svensson, Bengt, Thomas, David D.

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Conformational Changes in Actinin-type Actin Binding Domains: Probing Actininduced Structural Dynamics in Dystrophin and Utrophin using EPR Spectroscopy by Crain, Jonathan

“…The underlying cause of Duchenne and Becker muscular dystrophies is a lack of functional dystrophin, a large multidomain protein. Dystrophin is normally…”
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A human [beta]-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding by Avery, Adam W, Crain, Jonathan, Thomas, David D, Hays, Thomas S

“…Spinocerebellar ataxia type 5 (SCA5) is a human neurodegenerative disease that stems from mutations in the SPTBN2 gene encoding the protein β-III-spectrin…”
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