Search Results - "Craik, D.J"
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Discovery and applications of naturally occurring cyclic peptides
Published in Drug discovery today. Technologies (2012)“…Over the last decade several families of naturally occurring cyclic peptides have been discovered that are extremely stable and have important roles as defense…”
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Structure and function of Fugu parathyroid hormone 1 (–34)
Published in Bone (New York, N.Y.) (01-05-2009)Get full text
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Circular proteins — no end in sight
Published in Trends in Biochemical Sciences (01-03-2002)“…Circular proteins are a recently discovered phenomenon. They presumably evolved to confer advantages over ancestral linear proteins while maintaining the…”
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PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer
Published in Oncogene (03-07-2014)“…Caveolin-1 has a complex role in prostate cancer and has been suggested to be a potential biomarker and therapeutic target. As mature caveolin-1 resides in…”
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The Yariv reagent: Behaviour in different solvents and interaction with a gum arabic arabinogalactanprotein
Published in Carbohydrate polymers (15-06-2014)Get full text
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Backbone Cyclised Peptides from Plants Show Molluscicidal Activity against the Rice Pest Pomacea canaliculata (Golden Apple Snail)
Published in Journal of agricultural and food chemistry (09-07-2008)“…Golden apple snails (Pomacea canaliculata) are serious pests of rice in South East Asia. Cyclotides are backbone cyclized peptides produced by plants from…”
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Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedoensis
Published in Journal of natural products (Washington, D.C.) (01-01-2008)“…Cyclotides are macrocyclic plant peptides characterized by a knotted arrangement of three disulfide bonds. They display a range of interesting bioactivities,…”
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Tissue specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1
Published in The Plant cell (01-08-2004)“…The plant cyclotides are a family of 28 to 37 amino acid miniproteins characterized by their head-to-tail cyclized peptide backbone and six absolutely…”
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Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif
Published in Journal of molecular biology (17-12-1999)“…Several macrocyclic peptides (∼30 amino acids), with diverse biological activities, have been isolated from the Rubiaceae and Violaceae plant families over…”
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Conotoxin modulation of voltage-gated sodium channels
Published in The international journal of biochemistry & cell biology (2008)“…The rising phase of the action potential in excitable cells is mediated by voltage-gated sodium channels (VGSCs), of which there are nine mammalian subtypes…”
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Scanning mutagenesis of α-conotoxin AuIB reveals a critical residue for activity at the α3β4 nicotinic acetylcholine receptor
Published in Biochemical pharmacology (01-10-2011)Get full text
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The three-dimensional solution structure by 1H NMR of a 6-kDa proteinase inhibitor isolated from the stigma of Nicotiana alata
Published in Journal of molecular biology (23-09-1994)“…The three-dimensional structure and disulfide connectivities of a 6-kDa protein isolated from the stigma of the ornamental tobacco Nicotiana alata has been…”
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Variations in Cyclotide Expression in Viola Species
Published in Journal of natural products (Washington, D.C.) (01-05-2004)“…Cyclotides, a family of approximately 50 mini-proteins isolated from various Violaceae and Rubiaceae plants, are characterized by their circular peptide…”
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Cycloviolacin H4, a Hydrophobic Cyclotide from Viola hederaceae
Published in Journal of natural products (Washington, D.C.) (01-01-2006)“…Cycloviolacin H4, a new macrocyclic miniprotein comprising 30 amino acid residues, was isolated from the underground parts of the Australian native violet…”
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New indole alkaloids from the bark of Alstonia scholaris
Published in Journal of natural products (Washington, D.C.) (01-09-2004)“…A new indole alkaloid, akuammiginone (1), and a new glycosidic indole alkaloid, echitamidine-N-oxide 19-O-beta-d-glucopyranoside (2), together with the five…”
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Peptide quantification by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry: Investigations of the cyclotide kalata B1 in biological fluids
Published in Journal of Chromatography A (14-10-2005)“…A rapid method has been developed for the quantification of the prototypic cyclotide kalata B1 in water and plasma utilizing matrix-assisted laser desorption…”
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Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity
Published in Journal of molecular biology (08-01-1999)“…The three-dimensional solution structure of circulin A, a 30 residue polypeptide from the African plant Chassalia parvifolia, has been determined using…”
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New alkaloids from Pandanus amaryllifolius
Published in Journal of natural products (Washington, D.C.) (01-01-2004)“…Three new alkaloids, the two pyrrolidine type alkaloids (1 and 2) and 6E-pandanamine (3), together with five known alkaloids (4-8), were isolated from the…”
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