Search Results - "Craig Moore, W."

Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: a late-stage diversification approach to potent 5HT1B antagonists by Horchler, Carey L, McCauley, Jr, John P, Hall, James E, Snyder, Dean H, Craig Moore, W, Hudzik, Thomas J, Chapdelaine, Marc J

“…Multiparallel amenable syntheses of 6-methoxy-8-amino-4-oxo-1,4-dihydroquinoline-2-carboxylic acid-(4-morpholin-4-yl-phenyl)amides (I) and…”
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Calcium mobilization and entry by thapsigargin in neuronal tumor cell line, SK-N-SH by Moore, W C, Hargrove, H M, Salama, A I, Patel, J

“…Using fura-2 loaded neural tumour cells, SK-N-SH, we demonstrate that receptor-mediated activation of phosphoinositide hydrolysis not only causes the release…”
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Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: A late-stage diversification approach to potent 5HT 1B antagonists by Horchler, Carey L., McCauley, John P., Hall, James E., Snyder, Dean H., Craig Moore, W., Hudzik, Thomas J., Chapdelaine, Marc J.

“…MPS amenable syntheses of novel potent 5HT1b antagonists, 6-methoxy-8-amino-4-oxo-1,4-dihydroquinoline-2-carboxylic acid-(4-morpholin-4-yl-phenyl)amides ( I)…”
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The cloned neurotensin receptor mediates cyclic GMP formation when coexpressed with nitric oxide synthase cDNA by Slusher, B S, Zacco, A E, Maslanski, J A, Norris, T E, McLane, M W, Moore, W C, Rogers, N E, Ignarro, L J

“…Rat neurotensin (NT) receptor (NTR) cDNA was subcloned into the pRC-CMV expression vector and transfected into 293 cells, and cellular clones that stably…”
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Characterization of the quisqualate receptor linked to phosphoinositide hydrolysis in neurocortical cultures by Patel, J, Moore, W C, Thompson, C, Keith, R A, Salama, A I

“…Activation of phosphoinositide metabolism is an early event in signal transduction for a number of neurotransmitters and hormones. In primary cultures of rat…”
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Role of calcium in regulation of phosphoinositide signaling pathway by Patel, J, Keith, R A, Salama, A I, Moore, W C

“…Using primary neuronal cultures we have examined the role of extracellular Ca2+ in a receptor-regulated phosphoinositide turnover. We report that receptor…”
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Leukotriene D4 increases both the force of contraction and polyphosphoinositide formation in guinea-pig papillary muscle by Falcone, R C, Moore, W C, Aharony, D, Scott, A L, Siegl, P K, Orzechowski, R F

“…Leukotriene D4 (LTD4) increased the force of contraction in guinea-pig papillary muscle. A rapid (less than 1 min), transient (less than 5 min) response to…”
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Group purchasing: past, present and future by Moore, C W

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Ibotenic acid mediates neurotoxicity and phosphoinositide hydrolysis by independent receptor mechanisms by ZINKAND, W. C, MOORE, W. C, THOMPSON, C, SALAMA, A. I, PATEL, J

“…Ibotenic acid (Ibo) has been shown to have agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor…”
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