Search Results - "Craig Alexander"

Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA by Kurtz, David M., Soo, Joanne, Co Ting Keh, Lyron, Alig, Stefan, Chabon, Jacob J., Sworder, Brian J., Schultz, Andre, Jin, Michael C., Scherer, Florian, Garofalo, Andrea, Macaulay, Charles W., Hamilton, Emily G., Chen, Binbin, Olsen, Mari, Schroers-Martin, Joseph G., Craig, Alexander F. M., Moding, Everett J., Esfahani, Mohammad S., Liu, Chih Long, Dührsen, Ulrich, Hüttmann, Andreas, Casasnovas, René-Olivier, Westin, Jason R., Roschewski, Mark, Wilson, Wyndham H., Gaidano, Gianluca, Rossi, Davide, Diehn, Maximilian, Alizadeh, Ash A.

“…Circulating tumor-derived DNA (ctDNA) is an emerging biomarker for many cancers, but the limited sensitivity of current detection methods reduces its utility…”
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Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma by Kurtz, David M, Scherer, Florian, Jin, Michael C, Soo, Joanne, Craig, Alexander F M, Esfahani, Mohammad Shahrokh, Chabon, Jacob J, Stehr, Henning, Liu, Chih Long, Tibshirani, Robert, Maeda, Lauren S, Gupta, Neel K, Khodadoust, Michael S, Advani, Ranjana H, Levy, Ronald, Newman, Aaron M, Dührsen, Ulrich, Hüttmann, Andreas, Meignan, Michel, Casasnovas, René-Olivier, Westin, Jason R, Roschewski, Mark, Wilson, Wyndham H, Gaidano, Gianluca, Rossi, Davide, Diehn, Maximilian, Alizadeh, Ash A

“…Outcomes for patients with diffuse large B-cell lymphoma remain heterogeneous, with existing methods failing to consistently predict treatment failure. We…”
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Liquid biopsy in lymphoma: Molecular methods and clinical applications by Cirillo, Melita, Craig, Alexander F.M., Borchmann, Sven, Kurtz, David M.

“…•Can detect small amounts of circulating tumor DNA from a single blood test.•Emerges as a viable method of tumor genotyping in most lymphoma subtypes.•Has the…”
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Freedom in context: A review essay of The Dialectics of Liberty by Craig, Alexander W.

“…The contributors to The Dialectics of Liberty demonstrate that libertarians can engage in a careful context-sensitive analysis of social behavior and political…”
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Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA by Scherer, Florian, Kurtz, David M, Newman, Aaron M, Stehr, Henning, Craig, Alexander F M, Esfahani, Mohammad Shahrokh, Lovejoy, Alexander F, Chabon, Jacob J, Klass, Daniel M, Liu, Chih Long, Zhou, Li, Glover, Cynthia, Visser, Brendan C, Poultsides, George A, Advani, Ranjana H, Maeda, Lauren S, Gupta, Neel K, Levy, Ronald, Ohgami, Robert S, Kunder, Christian A, Diehn, Maximilian, Alizadeh, Ash A

“…Patients with diffuse large B cell lymphoma (DLBCL) exhibit marked diversity in tumor behavior and outcomes, yet the identification of poor-risk groups remains…”
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Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas by Sworder, Brian J., Kurtz, David M., Alig, Stefan K., Frank, Matthew J., Shukla, Navika, Garofalo, Andrea, Macaulay, Charles W., Shahrokh Esfahani, Mohammad, Olsen, Mari N., Hamilton, James, Hosoya, Hitomi, Hamilton, Mark, Spiegel, Jay Y., Baird, John H., Sugio, Takeshi, Carleton, Mia, Craig, Alexander F.M., Younes, Sheren F., Sahaf, Bita, Sheybani, Natasha D., Schroers-Martin, Joseph G., Liu, Chih Long, Oak, Jean S., Jin, Michael C., Beygi, Sara, Hüttmann, Andreas, Hanoun, Christine, Dührsen, Ulrich, Westin, Jason R., Khodadoust, Michael S., Natkunam, Yasodha, Majzner, Robbie G., Mackall, Crystal L., Diehn, Maximilian, Miklos, David B., Alizadeh, Ash A.

“…Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19 chimeric antigen receptor (CAR19) T cells relapse. To characterize…”
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Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma by Alig, Stefan, Macaulay, Charles W, Kurtz, David M, Dührsen, Ulrich, Hüttmann, Andreas, Schmitz, Christine, Jin, Michael C, Sworder, Brian J, Garofalo, Andrea, Shahrokh Esfahani, Mohammad, Nabet, Barzin Y, Soo, Joanne, Scherer, Florian, Craig, Alexander F M, Casasnovas, Olivier, Westin, Jason R, Gaidano, Gianluca, Rossi, Davide, Roschewski, Mark, Wilson, Wyndham H, Meignan, Michel, Diehn, Maximilian, Alizadeh, Ash A

“…Patients with Diffuse Large B-cell Lymphoma (DLBCL) in need of immediate therapy are largely under-represented in clinical trials. The diagnosis-to-treatment…”
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Ultralarge Virtual Screening Identifies SARS-CoV‑2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses by Luttens, Andreas, Gullberg, Hjalmar, Abdurakhmanov, Eldar, Vo, Duy Duc, Akaberi, Dario, Talibov, Vladimir O, Nekhotiaeva, Natalia, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Krambrich, Janina, Tas, Ali, Lundgren, Bo, Gravenfors, Ylva, Craig, Alexander J, Atilaw, Yoseph, Sandström, Anja, Moodie, Lindon W. K, Lundkvist, Åke, van Hemert, Martijn J, Neyts, Johan, Lennerstrand, Johan, Kihlberg, Jan, Sandberg, Kristian, Danielson, U. Helena, Carlsson, Jens

“…Drugs targeting SARS-CoV-2 could have saved millions of lives during the COVID-19 pandemic, and it is now crucial to develop inhibitors of coronavirus…”
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Preparation of Simple Bicyclic Carboxylate-Rich Alicyclic Molecules for the Investigation of Dissolved Organic Matter by Craig, Alexander J., Moodie, Lindon W. K., Hawkes, Jeffrey A.

“…Dissolved organic matter (DOM) is a vast and complex chemical mixture that plays a key role in the mediation of the global carbon cycle. Fundamental…”
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ALK+ ALCL in the setting of adalimumab‐related hidradenitis suppurativa by Craig, Alexander, Wen, Kwun Wah

“…This ALK‐positive anaplastic large cell lymphoma (ALCL) case highlights the importance of considering ALCL in the setting of iatrogenic immunosuppression in…”
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Characterization of a Newly Available Coastal Marine Dissolved Organic Matter Reference Material (TRM-0522) by Felgate, Stacey L., Craig, Alexander J., Moodie, Lindon W. K., Hawkes, Jeffrey

“…Recent methodological advances have greatly increased our ability to characterize aquatic dissolved organic matter (DOM) using high-resolution instrumentation,…”
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Does the Reaction of Cyclopropyl Acid Chlorides and Imines To Form 1,3-Oxazin-4-enone Heterocycles Proceed via a Ketene or an N‑Acyl-iminium Mechanism? by Craig, Alexander J, Cording, Andrew P, Garden, Anna L, Hawkins, Bill C

“…The mechanism of the reaction between cyclopropyl acid chlorides and imines to form 1,3-oxazin-4-enones was probed through physical and computational…”
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Condition monitoring of naturally damaged slow speed slewing bearing based on ensemble empirical mode decomposition by Caesarendra, Wahyu, Kosasih, Prabuono Buyung, Tieu, Anh Kiet, Moodie, Craig Alexander Simpson, Choi, Byeong-Keun

“…There have been extensive studies on vibration based condition monitoring, prognosis of rotating element bearings; and reviews of the methods on how to…”
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Phased Variant Enrichment for Enhanced Minimal Residual Disease Detection from Cell-Free DNA by Kurtz, David M., Soo, Joanne, Alig, Stefan, Keh, Lyron Co Ting, Macaulay, Charles, Jin, Michael C., Scherer, Florian, Hamilton, Emily G., Liu, Chih Long, Chen, Binbin, Craig, Alexander F.M., Diehn, Maximilian, Alizadeh, Ash A.

“…Background: Circulating tumor DNA (ctDNA) is an emerging biomarker in non-Hodgkin lymphomas (NHLs). Current methods for ctDNA minimal residual disease (MRD)…”
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Towards Non-Invasive Classification of DLBCL Genetic Subtypes By Ctdna Profiling by Esfahani, Mohammad Shahrokh, Alig, Stefan, Kurtz, David M., Soo, Joanne, Jin, Michael C., Macaulay, Charles, Craig, Alexander F.M., Garofalo, Andrea, Steen, Chloe B., Scherer, Florian, Sworder, Brian, Diehn, Maximilian, Alizadeh, Ash A.

“…Background Diffuse large B-cell lymphoma (DLBCL) is a genetically and clinically heterogeneous disease. The cell-of-origin (COO) classification subdivides…”
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Profiling T-Cell Receptor Diversity and Dynamics during Lymphoma Immunotherapy Using Cell-Free DNA (cfDNA) by Shukla, Navika D, Craig, Alexander F.M., Sworder, Brian, Kurtz, David M., Macaulay, Charles, Garofalo, Andrea, Frank, Matthew J., Alig, Stefan, Duran, George, Kim, Youn H., Zehnder, James, Mackall, Crystal L., Miklos, David B., Diehn, Maximilian, Khodadoust, Michael S., Alizadeh, Ash A.

“…Background: Characterization of T-cell receptor (TCR) diversity and dynamics is increasingly critical to understanding therapeutic immune responses targeting…”
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Bendamustine, Obinutuzumab and Venetoclax As Induction Therapy for Untreated Mantle Cell Lymphoma by Greenwell, Irl Brian, Switchenko, Jeffrey M., Maddocks, Kami J., Kahl, Brad S., Craig, Alexander F.M., Alizadeh, Ash A., Allen, Pamela B., Marbury, Alena Lorretta, Escobar, Alicia, Valla, Kelly, Williams, Miayea, Parikh, Priya, Roberts, Danielle, Neely, Jessica J., Palmer, Alexandra, Blum, Kristie A., Cohen, Jonathon B.

“…Bendamustine-rituximab (BR) is a standard of care for patients with mantle cell lymphoma (MCL) with median progression free survival (PFS) of approximately 3…”
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Impact of Self-Heating on the Statistical Variability in Bulk and SOI FinFETs by Liping Wang, Brown, Andrew R., Nedjalkov, Mihail, Alexander, Craig, Cheng, Binjie, Millar, Campbell, Asenov, Asen

“…In this paper, for the first time, we study the impact of self-heating on the statistical variability of bulk and Silicon-on-insulator FinFETs designed to meet…”
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A phase 1/2 study of lenalidomide and obinutuzumab with CHOP for newly diagnosed DLBCL by Cherng, Hua-Jay J., Alig, Stefan K., Oki, Yasuhiro, Nastoupil, Loretta J., Fayad, Luis, Neelapu, Sattva S., Turturro, Francesco, Hagemeister, Fredrick, Craig, Alexander F. M., Macaulay, Charles W., Rodriguez, Maria Alma, Lee, Hun Ju, McDonnell, Timothy J., Flowers, Christopher R., Vega, Francisco, Green, Michael R., Feng, Lei, Kurtz, David M., Alizadeh, Ash A., Davis, R. Eric, Westin, Jason R.

“…•Lenalidomide, obintuzumab, and CHOP chemotherapy are efficacious and well tolerated treatments for newly diagnosed DLBCL.•LO-CHOP led to high molecular…”
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Telemedicine for Neurosurgery Consultations at a Pituitary Center of Excellence: Patient Preference and Willingness to Proceed with Surgery by Greven, Alexander Craig McConnell, Douglas, James Miller, Couceyro, Jordan, Nakirikanti, Anudeep, Dawoud, Reem, Revuelta-Barbero, Manuel, Ward, Elisabeth, Giraldi, Erica Alexandra, Ioachimescu, Adriana, Hoang, Kimberly Bojanowski, Bray, David Painton, Oyesiku, Nelson M

“…The purpose of this study was to evaluate pituitary tumor patient satisfaction with telemedicine, patient preference for telemedicine, potential socioeconomic…”
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