Search Results - "Craig, Thelma R"

A Randomized Clinical Trial of Hydroxymethylglutaryl― Coenzyme A Reductase Inhibition for Acute Lung Injury (The HARP Study) by CRAIG, Thelma R, DUFFY, Martin J, SHYAMSUNDAR, Murali, MCDOWELL, Cliona, O'KANE, Cecilia M, STUART ELBORN, J, MCAULEY, Daniel F

“…There is no effective pharmacological treatment for acute lung injury (ALI). Statins are a potential new therapy because they modify many of the underlying…”
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Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers by Shyamsundar, Murali, McKeown, Scott T. W, O'Kane, Cecilia M, Craig, Thelma R, Brown, Vanessa, Thickett, David R, Matthay, Michael A, Taggart, Clifford C, Backman, Janne T, Elborn, J. Stuart, McAuley, Daniel F

“…Simvastatin inhibits inflammatory responses in vitro and in murine models of lung inflammation in vivo. As simvastatin modulates a number of the underlying…”
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Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury by Craig, Thelma R, Duffy, Martin J, Shyamsundar, Murali, McDowell, Cliona, McLaughlin, Brian, Elborn, J Stuart, McAuley, Daniel F

“…OBJECTIVES:Acute lung injury and the acute respiratory distress syndrome are characterized by noncardiogenic pulmonary edema, which can be assessed by…”
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Impaired endothelium-dependent vasodilatation is a novel predictor of mortality in intensive care by Duffy, Martin J, Mullan, Brian A, Craig, Thelma R, Shyamsundar, Murali, MacSweeney, Rob E, Thompson, Gillian, Stevenson, Michael, McAuley, Daniel F

“…OBJECTIVE:Endothelial function may be impaired in critical illness. We hypothesized that impaired endothelium-dependent vasodilatation is a predictor of…”
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Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury by McAuley, Daniel F, O'Kane, Cecilia M, Craig, Thelma R, Shyamsundar, Murali, Herwald, Heiko, Dib, Karim

“…Heparin-binding protein is released by neutrophils during inflammation and disrupts the integrity of the alveolar and capillary endothelial barrier implicated…”
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Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury by Brown, Lisa M, Calfee, Carolyn S, Howard, James P, Craig, Thelma R, Matthay, Michael A, McAuley, Daniel F

“…Background Acute lung injury and the acute respiratory distress syndrome (ALI/ARDS) are characterized by pulmonary oedema, measured as extravascular lung water…”
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