Search Results - "Craig, Okada"

Cyclin-Dependent Kinase-9 Is a Therapeutic Target in MYC-Expressing Diffuse Large B-Cell Lymphoma by Hashiguchi, Taylor, Bruss, Nur, Best, Scott, Lam, Vi, Danilova, Olga, Paiva, Cody J, Wolf, Joelle, Gilbert, Erin W, Okada, Craig Y, Kaur, Prabhjot, Drew, Lisa, Cidado, Justin, Hurlin, Peter, Danilov, Alexey V

“…Deregulation of the MYC transcription factor is a key driver in lymphomagenesis. MYC induces global changes in gene expression that contribute to cell growth,…”
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Colorectal Lymphoma: A Review by Gay, Nathan D, Chen, Andy, Okada, Craig Y

“…Non-Hodgkin lymphoma (NHL) that primarily involves the colon is rare and should be distinguished from the more common systemic nodal lymphoma. It has unique…”
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Safety and efficacy of tenalisib in combination with romidepsin in patients with relapsed/refractory T-cell lymphoma: results from a phase I/II open-label multicenter study by Iyer, Swaminathan P, Huen, Auris, Ai, Weiyun Z, Jagadeesh, Deepa, Lechowicz, Mary J, Okada, Craig, Feldman, Tatyana A, Ghione, Paola, Alderuccio, Juan P, Champion, Rebecca, Kim, Seo-Hyun, Mohrbacher, Ann, Routhu, Kasi V, Barde, Prajak, Nair, Ajit M, Haverkos, Bradley M

“…Tenalisib, a selective phosphoinositide-3-kinase δ/γ, and salt-inducible-kinase-3 inhibitor has shown efficacy and was well-tolerated in patients with T-cell…”
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Entospletinib and obinutuzumab in patients with relapsed/refractory chronic lymphocytic leukemia and B-cell malignancies by Kittai, Adam S, Best, Scott, Thurlow, Bria, Lam, Vi, Hashiguchi, Taylor, Goodyear, Shaun, Persky, Daniel O, Okada, Craig, Park, Byung, Spurgeon, Stephen E, Danilov, Alexey V

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Vesiculobullous eruption with loncastuximab tesirine in a patient with relapsed follicular lymphoma by Seervai, Riyad N.H., Okada, Craig Y., Mengden-Koon, Stephanie J., Hornick, Noah I.

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Outcomes of DA-EPOCH-R induction plus autologous transplant consolidation for double hit lymphoma by Chen, Andy I., Leonard, Jessica T., Okada, Craig Y., Gay, Nathan D., Chansky, Kari, Fan, Guang, Dunlap, Jennifer B., Raess, Philipp W., Braziel, Rita M., Stentz, Alex, Maziarz, Richard T.

“…High-grade B cell lymphoma with MYC and BCL2 rearrangements (double hit) has a poor prognosis with standard R-CHOP (rituximab, cyclophosphamide, doxorubicin,…”
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Phase 1/2 study of intratumoral G100 (TLR4 agonist) with or without pembrolizumab in follicular lymphoma by Halwani, Ahmad S., Panizo, Carlos, Isufi, Iris, Herrera, Alex F., Okada, Craig Y., Cull, Elizabeth H., Kis, Bela, Chaves, Jorge M., Bartlett, Nancy L., Ai, Weiyun, de la Cruz-Merino, Luis, Bryan, Locke J., Houot, Roch, Linton, Kim, Briones, Javier, Chau, Ian, von Keudell, Gottfried R., Lu, Hailing, Yakovich, Adam, Chen, Michael, Meulen JH, ter, Yurasov, Sergey, Hsu, Frank J., Flowers, Christopher R.

“…Intratumoral injection of G100, a toll-like receptor 4 (TLR4) agonist, was shown pre-clinically to stimulate anti-tumor immune responses and tumor regression…”
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Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients by Timmerman, John M., Czerwinski, Debra K., Davis, Thomas A., Hsu, Frank J., Benike, Claudia, Hao, Zheng Mei, Taidi, Behnaz, Rajapaksa, Ranjani, Caspar, Clemens B., Okada, Craig Y., van Beckhoven, Adrienne, Liles, Tina Marie, Engleman, Edgar G., Levy, Ronald

“…Tumor-specific clonal immunoglobulin expressed by B-cell lymphomas (idiotype [Id]) can serve as a target for active immunotherapy. We have previously described…”
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Targeting ubiquitin-activating enzyme induces ER stress–mediated apoptosis in B-cell lymphoma cells by Best, Scott, Hashiguchi, Taylor, Kittai, Adam, Bruss, Nur, Paiva, Cody, Okada, Craig, Liu, Tingting, Berger, Allison, Danilov, Alexey V.

“…Alterations in the ubiquitin proteasome system (UPS) leave malignant cells in heightened cellular stress, making them susceptible to proteasome inhibition…”
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Gene expression and angiotropism in primary CNS lymphoma by Rubenstein, James L., Fridlyand, Jane, Shen, Arthur, Aldape, Ken, Ginzinger, David, Batchelor, Tracy, Treseler, Patrick, Berger, Mitchel, McDermott, Michael, Prados, Michael, Karch, Jon, Okada, Craig, Hyun, William, Parikh, Seema, Haqq, Chris, Shuman, Marc

“…Primary CNS lymphoma is an aggressive form of non-Hodgkin lymphoma whose growth is restricted to the central nervous system. We used cDNA microarray analysis…”
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Primary cutaneous Epstein-Barr virus-positive diffuse large B-cell lymphoma (DLBCL) in a patient taking fingolimod by Wills, Abby, Fan, Guang, Kim, Edward, Okada, Craig Y, White, Kevin P, Hopkins, R Samuel

“…A 55-year-old man with relapsing-remitting multiple sclerosis on fingolimod presented to the dermatology clinic with skin lesions on the left temple and cheek…”
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Targeting the programmed cell death 1 pathway in Hodgkin lymphoma: the place of nivolumab by Gay, Nathan D., Okada, Craig Y., Chen, Andy I., Scott, Emma C.

“…Nivolumab is a humanized immunoglobulin gamma-4 kappa anti-programmed cell death 1 monoclonal antibody that is currently approved in the treatment of several…”
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Tumor Cell Lysate-Pulsed Dendritic Cells Are More Effective Than TCR Id Protein Vaccines for Active Immunotherapy of T Cell Lymphoma by Gatza, Erin, Okada, Craig Y

“…TCR Id protein conjugated to keyhole limpet hemocyanin (KLH) (TCR Id:KLH) and injected with a chemical adjuvant (QS-21) induces a protective, Id-specific…”
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Adjuvant IL-15 does not enhance the efficacy of tumor cell lysate-pulsed dendritic cell vaccines for active immunotherapy of T cell lymphoma by GATZA, Erin, OKADA, Craig Y

“…There has been a recent interest in using IL-15 to enhance antitumor activity in several models because of its ability to stimulate CD8+ T cell expansion,…”
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TCR Vaccines against a Murine T Cell Lymphoma: A Primary Role for Antibodies of the IgG2c Class in Tumor Protection by Lambert, Stacie L, Okada, Craig Y, Levy, Ronald

“…Tumor-associated proteins can act as effective immunotherapeutic targets. Immunization with tumor TCR protein conjugated to the immunogenic protein keyhole…”
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Recurrent fibrin associated diffuse large B-cell lymphoma: A case report by Maedeh, Mohebnasab, Francisco, Tria, Sunny, Kim, Craig, Okada, Jessica, Davis, Guang, Fan

“…Fibrin- associated diffuse large B cell lymphoma (FA-DLBCL) is a rare entity, often incidental finding, categorized under “diffuse large B cell lymphoma…”
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TCR Vaccines Against T Cell Lymphoma: QS-21 and IL-12 Adjuvants Induce a Protective CD8+ T Cell Response by Wong, Carmen P, Okada, Craig Y, Levy, Ronald

“…Tumor-specific TCR can serve as an effective target for active immunotherapy of T cell malignancies. Using the murine T cell tumor model C6VL, vaccination with…”
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Galloping Ophthalmoplegia and Numb Chin in Burkitt Lymphoma by Chan Lau, Juan J, Okada, Craig Y, Trobe, Jonathan D

“…A 57-year-old man developed complete bilateral ophthalmoplegia over a period of 10 days, together with bilateral facial pain and numbness of the chin. He had…”
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Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells by Kittai, Adam, Best, Scott R, Rowland, Taylor, Bruss, Nur, Okada, Craig, Danilov, Alexey V

“…Introduction: Despite the significant progress of targeted therapies in B-cell malignancies, T-cell lymphomas remain an area of unmet medical need. Most…”
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Phase 1b Open-Label Study of Loncastuximab Tesirine in Combination With Other Anticancer Agents in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7) by Ayers, Emily C., Depaus, Julien, Offner, Fritz, Hu, Marie, Okada, Craig, Urban, Andrzej, Niewiarowski, Andrew, Rave, Erica, Laughlin, Mary, Pablo Alderuccio, Juan

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