Search Results - "Craig, Heather C"

The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance by Hurst, Jacklyn R, Shannon, Blake A, Craig, Heather C, Rishi, Aanchal, Tuffs, Stephen W, McCormick, John K

“…Streptococcus pyogenes is a globally prominent human-specific pathogen responsible for an enormous burden of human illnesses, including >600 million pharyngeal…”
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Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice by Shannon, Blake A, Hurst, Jacklyn R, Flannagan, Ronald S, Craig, Heather C, Rishi, Aanchal, Kasper, Katherine J, Tuffs, Stephen W, Heinrichs, David E, McCormick, John K

“…Streptococcus pyogenes is a human-specific pathogen that commonly colonizes the upper respiratory tract and skin, causing a wide variety of diseases ranging…”
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Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease by Dang, Amy K, Tesfagiorgis, Yodit, Jain, Rajiv W, Craig, Heather C, Kerfoot, Steven M

“…We characterized B cell infiltration of the spinal cord in a B cell-dependent spontaneous model of central nervous system (CNS) autoimmunity that develops in a…”
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Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance by Jain, Rajiv W., Parham, Kate A., Tesfagiorgis, Yodit, Craig, Heather C., Romanchik, Emiliano, Kerfoot, Steven M.

“…B cell fate decisions within a germinal center (GC) are critical to determining the outcome of the immune response to a given antigen. Here, we characterize GC…”
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Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity by Tesfagiorgis, Yodit, Kemal, Eden A., Craig, Heather C., Parham, Kate A., Kerfoot, Steven M.

“…Anti-CD20 B cell depleting therapies have demonstrated that B cells are important drivers of disease progress in Multiple Sclerosis, although the pathogenic…”
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Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production by Tuffs, Stephen W, Goncheva, Mariya I, Xu, Stacey X, Craig, Heather C, Kasper, Katherine J, Choi, Joshua, Flannagan, Ronald S, Kerfoot, Steven M, Heinrichs, David E, McCormick, John K

“…is a foremost bacterial pathogen responsible for a vast array of human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from that…”
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Pre–Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses by Parham, Kate A., Tan, Xiu Xia Sherry, Morelli, Daniel M., Chowdhury, Lika, Craig, Heather C., Kerfoot, Steven M.

“…Interactions with Ag-specific T cells drive B cell activation and fate choices that ultimately determine the quality of high-affinity Ab responses. As such,…”
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B cell recognition of myelin oligodendrocyte glycoprotein autoantigen depends on immunization with protein rather than short peptide, while B cell invasion of the CNS in autoimmunity does not by Dang, Amy K, Jain, Rajiv W, Craig, Heather C, Kerfoot, Steven M

“…Abstract We develop a new fusion protein reagent (MOGtag ), based on the extracellular domain of mouse myelin oligodendrocyte glycoprotein (MOG1–125 ),…”
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Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity by Kerfoot, Steven, Tesfagiorgis, Yodit, Kemal, Eden A, Craig, Heather C, Parham, Kate A

“…Anti-CD20 B cell depleting therapies have demonstrated that B cells are important drivers of disease progress in Multiple Sclerosis, although the pathogenic…”
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Characterization of the activation history and antigen specificity of B cells in meningeal clusters in Central Nervous System autoimmunity by Kerfoot, Steven, Tesfagiorgis, Yodit, Dang, Amy K, Zhu, Sarah, Craig, Heather C

“…An important role for B cells in the pathology of Multiple Sclerosis (MS) is demonstrated by the therapeutic benefit of broad B cell depletion by anti-CD20…”
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