Search Results - "Craig, Francis"

Synthesis and biological evaluation of 2-(Tetrazol-5-yl)sulfonylacetamides as inhibitors of Mycobacterium tuberculosis and Mycobacterium marinum by Henches, Robin, Ozga, Théo, Gao, Yamin, Tu, Zhengchao, Zhang, Tianyu, Francis, Craig L.

“…[Display omitted] •2-(Tetrazol-5-yl)sulfonylacetamides with potent in vitro inhibitory activity (MIC90 = 1.25 mg/mL) against Mycobacterium tuberculosis.•Highly…”
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1,3-Disubstituted-1,2,4-triazin-6-ones with potent activity against androgen receptor-dependent prostate cancer cells by Zhao, Shiting, Ali, Abdelsalam S., Liu, Xiaomin, Yu, Zhiwei, Kong, Xinyu, Zhang, Yan, Paul Savage, G., Xu, Yong, Lin, Bin, Wu, Donghai, Francis, Craig L.

“…[Display omitted] Synthesis and biological evaluation of a small, focused library of 1,3-disubstituted-1,2,4-triazin-6-ones for in vitro inhibitory activity…”
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3-Methoxy-2-phenylimidazo[1,2-b]pyridazines highly active against Mycobacterium tuberculosis and Mycobacterium marinum by Farrell, Kyle D., Gao, Yamin, Hughes, Deborah A., Henches, Robin, Tu, Zhengchao, Perkins, Michael V., Zhang, Tianyu, Francis, Craig L.

“…A series of 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivatives which were highly active against autoluminescent Mycobacterium tuberculosis (Mtb) and…”
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Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design by Peat, Thomas S, Rhodes, David I, Vandegraaff, Nick, Le, Giang, Smith, Jessica A, Clark, Lisa J, Jones, Eric D, Coates, Jonathan A V, Thienthong, Neeranat, Newman, Janet, Dolezal, Olan, Mulder, Roger, Ryan, John H, Savage, G Paul, Francis, Craig L, Deadman, John J

“…A fragment-based screen against human immunodeficiency virus type 1 (HIV) integrase led to a number of compounds that bound to the lens epithelium derived…”
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1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells by Zhao, Shiting, Ali, Abdelsalam S., Kong, Xinyu, Zhang, Yan, Liu, Xiaomin, Skidmore, Melissa A., Forsyth, Craig M., Savage, G. Paul, Wu, Donghai, Xu, Yong, Francis, Craig L.

“…A series of 1-benzyloxy-5-phenyltetrazole derivatives and similar compounds were synthesized and evaluated for their in vitro inhibitory activity against…”
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5-Amino-3-(diethylamino)-5H-benzo[4,5]imidazo[1,2-b][1,2,4,6]thiatriazine 1,1-Dioxide by Tran, Victor, Forsyth, Craig, Francis, Craig

“…In the quest for discovery of novel bioactive molecules, new heterocyclic ring systems provide templates for exploration of uncharted chemical space. Herein,…”
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Laser-Generated Shockwaves as a Treatment to Reduce Bacterial Load and Disrupt Biofilm by Francis, Nathan Craig, Yao, William, Grundfest, Warren S., Taylor, Zachary Deis

“…Objective: The goal of this paper is to demonstrate and evaluate the potential efficacy of laser-generated shockwave (LGS) therapy on biofilm infected tissue…”
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New heteroatom-rich ring systems from N,N-dialkyl-N’-chlorosulfonyl chloroformamidines by Francis, Craig L.

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Crystal structures of two 2,3-di-ethyl-naphtho-[2,3- g ]quinoxaline-6,11-dione derivatives by Forsyth, Craig M, Francis, Craig L

“…Two new 5,12-disubstituted 2,3-di-ethyl-naphtho-[2,3- ]quinoxaline-6,11-dione compounds were readily synthesized from the commercial dye quinizarin. For…”
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Correction: Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design by Peat, Thomas S., Rhodes, David I., Vandegraaff, Nick, Le, Giang, Smith, Jessica A., Clark, Lisa J., Jones, Eric D., Coates, Jonathan A. V., Thienthong, Neeranat, Newman, Janet, Dolezal, Olan, Mulder, Roger, Ryan, John H., Savage, G. Paul, Francis, Craig L., Deadman, John J.

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2-Phenylimidazo[1,2- b]pyridazine derivatives highly active against Haemonchus contortus by Ali, Abdelselam, Cablewski, Teresa, Francis, Craig L., Ganguly, Ashit K., Sargent, Roger M., Sawutz, David G., Winzenberg, Kevin N.

“…A series of 2-phenylimidazo[1,2- b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus…”
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Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design by Rhodes, David I, Peat, Thomas S, Vandegraaff, Nick, Jeevarajah, Dharshini, Le, Giang, Jones, Eric D, Smith, Jessica A, Coates, Jonathan A V, Winfield, Lisa J, Thienthong, Neeranat, Newman, Janet, Lucent, Del, Ryan, John H, Savage, G Paul, Francis, Craig L, Deadman, John J

“…HIV-1 integrase is a clinically validated therapeutic target for the treatment of HIV-1 infection, with one approved therapeutic currently on the market. This…”
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Synthesis of (+)-Obtusenyne by Mak, S. Y. Frankie, Curtis, Neil R., Payne, Andrew N., Congreve, Miles S., Wildsmith, Andrew J., Francis, Craig L., Davies, John E., Pascu, Sofia I., Burton, Jonathan W., Holmes, Andrew B.

“…An enantioselective synthesis of the halogenated medium‐ring ether natural product (+)‐obtusenyne is reported which uses the ring expansion of a seven‐membered…”
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Protecting keratin fiber with water soluble N-substituted maleimides in high temperature processes by Cai, Jackie Y., McDonnell, Jill, Francis, Craig L., Church, Jeffrey S., Tsanaktsidis, John, Chiefari, John

“…This paper reports a facile method for protecting keratin fiber with water soluble N-substituted maleimides during high temperature processing in aqueous…”
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A controlled trial of an advanced access appointment system in a residency family medicine center by Belardi, Francis G, Weir, Sam, Craig, Francis W

“…The implementation of advanced access appointment systems has improved continuity of care, patient and physician satisfaction, physician productivity, and…”
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The changing landscape of organic chemistry in Australia by Francis, Craig L.

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Do a Little Dance: The Impact on Students when Librarians Get Involved in Extracurricular Activities by Kasperek, Sheila, Johnson, Amber, Fotta, Katie, Craig, Francis

“…One hundred fifty-two undergraduate students at Mansfield University of Pennsylvania were surveyed to determine if the involvement of their liaison librarian…”
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Patterns of cardiovascular responses during angry, sad, and happy emotional recall tasks by Dechert, Nathan T., Flack, William, Craig, Francis

“…Research on emotions and cardiovascular (CV) functioning has focused mainly on reactivity, and suggests that different emotions result in different patterns of…”
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Psychophysiological correlates of individual differences in patterns of hemodynamic reactivity by Lawler, Kathleen A., Kline, Keith A., Adlin, Richard F., Wilcox, Zachary C., Craig, Francis W., Krishnamoorthy, Jenelle S., Piferi, Rachel L.

“…The present study delineates a method for the quantification of six hemodynamic reactivity patterns, in response to a laboratory stressor, and examines the…”
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Fast switching immobilized photochromic dyes by Malic, Nino, Campbell, Jonathan A, Ali, Abdelselam S, Francis, Craig L, Evans, Richard A

“…A novel photochromic dye conjugate architecture is described, which allows both covalent tethering to a polymeric host matrix and fast photochromic switching…”
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