Search Results - "Craft, Timothy P."

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells by Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Herrbrich, Phillip E., Hohm, Sarah A., Lahey, Ryan, Eades, William C., Creer, Michael H., Nolta, Jan A.

“…The development of novel cell-based therapies requires understanding of distinct human hematopoietic stem and progenitor cell populations. We recently isolated…”
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Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity by Hess, David A., Meyerrose, Todd E., Wirthlin, Louisa, Craft, Timothy P., Herrbrich, Phillip E., Creer, Michael H., Nolta, Jan A.

“…Human hematopoietic stem cells (HSCs) are commonly purified by the expression of cell surface markers such as CD34. Because cell phenotype can be altered by…”
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Widespread Nonhematopoietic Tissue Distribution by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity by Hess, David A., Craft, Timothy P., Wirthlin, Louisa, Hohm, Sarah, Zhou, Ping, Eades, William C., Creer, Michael H., Sands, Mark S., Nolta, Jan A.

“…Transplanted adult progenitor cells distribute to peripheral organs and can promote endogenous cellular repair in damaged tissues. However, development of…”
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Rising medical education debt a mounting concern. Graduates also face less favorable repayment terms, shortage of training positions by Craft, 3rd, Joseph A, Craft, Timothy P

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Widespread Non-Hematopoietic Tissue Distribution by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity by Hess, David A., Craft, Timothy P., Wirthlin, Louisa, Hohm, Sarah, Zhou, Ping, Eades, William C., Creer, Michael H., Sands, Mark S., Nolta, Jan A.

“…Transplanted adult progenitor cells distribute to peripheral organs and can promote endogenous cellular repair in damaged tissues. However, development of…”
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Isolation of Human CD34- Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential by Hess, David A., Herrbrich, Phillip E., Wirthlin, Louisa, Craft, Timothy P., Nolta, Jan A.

“…The successful development of stem cell-based therapies requires a thorough understanding of human hematopoietic stem cell (HSC) populations. Human CD34− cells…”
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CD133-Expressing Cells with High Aldehyde Dehydrogenase Activity Represent a Primitive Human Hematopoietic Stem Cell Population with Enhanced Repopulating Potential by Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Meyerrose, Todd E., Nolta, Jan A.

“…Human hematopoietic stem cells (HSC) are commonly purified by the phenotypic expression of cell surface markers such as CD34. We have recently characterized a…”
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Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor by Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Bonde, Jesper, Lahey, Ryan W., Hohm, Sarah A., Herrbrich, Phillip E., DiPersio, John F., Devine, Steven M., Nolta, Jan A.

“…Interactions between stromal derived factor-1 (SDF-1 or CXCL12), and its receptor CXCR4 regulate hematopoietic stem and progenitor cell retention in the bone…”
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Human CD34+ Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Equivalent Efficiency as CD34+ Cells Mobilized by G-CSF by Hess, David A., Bonde, Jesper, Craft, Timothy P., Wirthlin, Louisa, DiPersio, John F., Devine, Steven M., Nolta, Jan A.

“…Interactions between the chemokine receptor CXCR4 and its ligand, stromal derived factor-1, regulate hematopoietic stem cell migration. The CXCR4 antagonist,…”
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Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model by Hess, David A., Craft, Timothy P., Wirthlin, Louisa, Herrbrich, Phillip E., Hofling, A. Alex, Sands, Mark S., Nolta, Jan A.

“…Beta-glucuronidase (GUSB) is a lysosomal enzyme expressed in virtually all human and murine cell types. Transplantation of GUSB-expressing human hematopoietic…”
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898. Human Hematopoietic Repopulating Stem and Progenitor Cells Can Be Efficiently Selected Based on High Aldehyde Dehydrogenase Activity by Hess, David A, Meyerrose, Todd E, Wirthlin, Louisa, Herrbrich, Phillip E, Craft, Timothy P, Nolta, Jan A

“…Human hematopoietic stem cells (HSC) are commonly purified by the expression of cell surface markers, such as CD34. Since cell phenotype can be altered by cell…”
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Human Progenitor Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Increased Frequency in Comparison to Cells from the Same Donor Mobilized by Granulocyte Colony Stimulating Factor by Hess, David A, Bonde, Jesper, Craft, Timothy C, Wirthlin, Louisa, Hohm, Sarah, Lahey, Ryan, Todt, Laura M, Dipersio, John F, Devine, Steven M, Nolta, Jan A

“…Abstract AMD3100 inhibits the interaction between SDF-1 and CXCR4, and rapidly mobilizes hematopoietic progenitors for clinical transplantation. However, the…”
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