Search Results - "Cradic, Kendall"

Clinical Evaluation and Utilization of Multiple Molecular In Vitro Diagnostic Assays for the Detection of SARS-CoV-2 by Cradic, Kendall, Lockhart, Marie, Ozbolt, Patrick, Fatica, Lisa, Landon, Lorie, Lieber, Michael, Yang, David, Swickard, Juanita, Wongchaowart, Nicholas, Fuhrman, Susan, Antonara, Stella

“…Abstract Objectives To evaluate the clinical performance of 3 molecular assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods We…”
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Managing Spectral Interferences Using Optical Coagulation Methods by Cradic, Kendall, Rosemark, Chris, Block, Darci, Baumann, Nikola

“…Abstract Background Both mechanical and optical-based methods are available for measuring prothrombin time (PT) and activated partial thromboplastin time…”
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BIMA V3: an aligner customized for mate pair library sequencing by Drucker, Travis M, Johnson, Sarah H, Murphy, Stephen J, Cradic, Kendall W, Therneau, Terry M, Vasmatzis, George

“…Mate pair library sequencing is an effective and economical method for detecting genomic structural variants and chromosomal abnormalities. Unfortunately, the…”
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Detection of SARS-CoV-2 infection in asymptomatic populations using the DiaSorin molecular Simplexa and Roche Cobas EUA assays by Antonara, Stella, Ozbolt, Patrick, Landon, Lorie, Fatica, Lisa, Pleasant, Tamra, Swickard, Juanita, Drury, Andrew, Wongchaowart, Nicholas, Cradic, Kendall W

“…Identification of asymptomatic patients is necessary to control the COVID-19 pandemic and testing is one of the measures to detect this population. We…”
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Monozygotic twins discordant for congenital adrenal hyperplasia due to mosaicism by Kluge, Michelle L, Graber, Evan, Foley, Kathryn, Hansen, Lynnette V, Sellers, Heidi L, Milosevic, Dragana, Cradic, Kendall W, Grebe, Stefan K

“…Introduction Genotype-phenotype discordance occurs occasionally in congenital adrenal hyperplasia (CAH). Its causes are largely unknown. We describe a case of…”
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RNA Sequencing Identifies Multiple Fusion Transcripts, Differentially Expressed Genes, and Reduced Expression of Immune Function Genes in BRAF (V600E) Mutant vs BRAF Wild-Type Papillary Thyroid Carcinoma by Smallridge, Robert C, Chindris, Ana-Maria, Asmann, Yan W, Casler, John D, Serie, Daniel J, Reddi, Honey V, Cradic, Kendall W, Rivera, Michael, Grebe, Stefan K, Necela, Brian M, Eberhardt, Norman L, Carr, Jennifer M, McIver, Bryan, Copland, John A, Thompson, E. Aubrey

“…Context: The BRAF V600E mutation (BRAF-MUT) confers an aggressive phenotype in papillary thyroid carcinoma, but unidentified additional genomic abnormalities…”
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Quantification of Serum 1-84 Parathyroid Hormone in Patients with Hyperparathyroidism by Immunocapture In Situ Digestion Liquid Chromatography-Tandem Mass Spectrometry by Kumar, Vivek, Barnidge, David R, Chen, Li-Sheng, Twentyman, Jolaine M, Cradic, Kendall W, Grebe, Stefan K, Singh, Ravinder J

“…Immunoassays specific for 1-84 parathyroid hormone (PTH) reportedly reflect the bioactivity of PTH; however, PTH immunoassays can be susceptible to…”
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Validation of the Cut-points Recommended for ROMA Using the Roche Elecsys CA125 and HE4 Assays by Cradic, Kendall W, Lasho, Michael A, Algeciras-Schimnich, Alicia

“…Assessing the risk of malignancy in patients with a pelvic mass helps triage women suspected of ovarian cancer to specialized gynecologic oncologists to…”
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Mutant BRAF(T1799A) can be detected in the blood of papillary thyroid carcinoma patients and correlates with disease status by Cradic, Kendall W, Milosevic, Dragana, Rosenberg, Anne M, Erickson, Lori A, McIver, Bryan, Grebe, Stefan K G

“…The BRAF(T1799A) transversion is the most frequent morphotype-specific somatic mutation in papillary thyroid carcinoma (PTC). The ability to detect this…”
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Development and Characterization of a Differentiated Thyroid Cancer Cell Line Resistant to VEGFR-Targeted Kinase Inhibitors by Isham, Crescent R, Netzel, Brian C, Bossou, Ayoko R, Milosevic, Dragana, Cradic, Kendall W, Grebe, Stefan K, Bible, Keith C

“…Background: Vascular endothelial growth factor-targeted kinase inhibitors have emerged as highly promising therapies for radioiodine-refractory metastatic…”
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Ionic cross talk can lead to overestimation of 3-methoxytyramine during quantification of metanephrines by mass spectrometry by Twentyman, Jolaine M, Cradic, Kendall W, Singh, Ravinder J, Grebe, Stefan K

“…Eisenhofer and others have used HPLC-electrochemical detection (HPLC-ECD) to measure 3MT in plasma (1-4). de Jong et al. developed an online solid-phase…”
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Clinical validation of a haplotyping method with next-generation sequencing by Cradic, Kendall W, Murphy, Stephen J, Sikkink, Robert A, Neuhauser, Claudia, Vasmatzis, George, Grebe, Stefan K G

“…Particularly problematic are recessive genes for which compound heterozygosity is relatively common, such as CYP21A2 (cytochrome P450, family 21, subfamily A,…”
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A simple method for gene phasing using mate pair sequencing by Cradic, Kendall W, Murphy, Stephen J, Drucker, Travis M, Sikkink, Robert A, Eberhardt, Norman L, Neuhauser, Claudia, Vasmatzis, George, Grebe, Stefan K G

“…Recessive genes cause disease when both copies are affected by mutant loci. Resolving the cis/trans relationship of variations has been an important problem…”
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Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl by Lodish, Maya B, Adams, Karen T, Huynh, Thanh T, Prodanov, Tamara, Ling, Alex, Chen, Clara, Shusterman, Suzanne, Jimenez, Camilo, Merino, Maria, Hughes, Marybeth, Cradic, Kendall W, Milosevic, Dragana, Singh, Ravinder J, Stratakis, Constantine A, Pacak, Karel

“…Organ of Zuckerkandl paragangliomas (PGLs) are rare neuroendocrine tumors that are derived from chromaffin cells located around the origin of the inferior…”
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Mutant BRAFT1799A Can Be Detected in the Blood of Papillary Thyroid Carcinoma Patients and Correlates with Disease Status by Cradic, Kendall W., Milosevic, Dragana, Rosenberg, Anne M., Erickson, Lori A., McIver, Bryan, Grebe, Stefan K. G.

“…Context: The BRAFT1799A transversion is the most frequent morphotype-specific somatic mutation in papillary thyroid carcinoma (PTC). The ability to detect this…”
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Determinants of Intra versus Intermolecular Self-association Within the Regulatory Domains of Rlk and Itk by Laederach, Alain, Cradic, Kendall W., Bruce Fulton, D., Andreotti, Amy H.

“…A protein fragment from the Tec family member Rlk (also known as Txk) containing a single proline-rich ligand adjacent to a Src homology 3 (SH3) domain has…”
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Substitution of 3'-phosphate cap with a carbon-based blocker reduces the possibility of fluorescence resonance energy transfer probe failure in real-time PCR assays by CRADIC, Kendall W, WELLS, Jason E, ALLEN, Lindsay, KRUCKEBERG, Kent E, SINGH, Ravinder J, GREBE, Stefan K. G

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Increasing Liquid Chromatography―Tandem Mass Spectrometry Throughput by Mass Tagging: A Sample-Multiplexed High-Throughput Assay for 25-Hydroxyvitamin D2 and D3 by NETZEL, Brian C, CRADIC, Kendall W, BRO, Eric T, GIRTMAN, Adam B, CYR, Richard C, SINGH, Ravinder J, GREBE, Stefan K. G

“…The limits of chromatographic speed and mechanical frontend capabilities have been reached for many high-volume liquid chromatography-tandem mass spectrometry…”
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Discordance of insulin-like growth factor-1 results and interpretation on four different platforms by Lee, Jason K.Y., Cradic, Kendall, Singh, Ravinder J., Jones, JoAnna, Li, Jieli

“…•There are wide variations between different platforms for IGF-1 measurement with discrepant reference ranges.•The potential impact of the variations in IGF-1…”
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Competing modes of self‐association in the regulatory domains of Bruton's tyrosine kinase: Intramolecular contact versus asymmetric homodimerization by Laederach, Alain, Cradic, Kendall W., Brazin, Kristine N., Zamoon, Jamillah, Fulton, D. Bruce, Huang, Xin‐Yun, Andreotti, Amy H.

“…A nuclear magnetic resonance (NMR) investigation of a fragment of the nonreceptor Tec family tyrosine kinase Btk has revealed an intricate set of coupled…”
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