Search Results - "Craddock, Travis J.A."

Cytoskeletal signaling: is memory encoded in microtubule lattices by CaMKII phosphorylation? by Craddock, Travis J A, Tuszynski, Jack A, Hameroff, Stuart

“…Memory is attributed to strengthened synaptic connections among particular brain neurons, yet synaptic membrane components are transient, whereas memories can…”
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Analysis of the Strength of Interfacial Hydrogen Bonds between Tubulin Dimers Using Quantum Theory of Atoms in Molecules by Ayoub, Ahmed T., Craddock, Travis J.A., Klobukowski, Mariusz, Tuszynski, Jack

“…Microtubules are key structural elements that, among numerous biological functions, maintain the cytoskeleton of the cell and have a major role in cell…”
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Fano resonance line shapes in the Raman spectra of tubulin and microtubules reveal quantum effects by Zhang, Wenxu, Craddock, Travis J.A., Li, Yajuan, Swartzlander, Mira, Alfano, Robert R., Shi, Lingyan

“…Microtubules are self-assembling biological nanotubes made of the protein tubulin that are essential for cell motility, cell architecture, cell division, and…”
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Periodically disturbing biofilms reduces expression of quorum sensing-regulated virulence factors in Pseudomonas aeruginosa by García-Diéguez, Laura, Diaz-Tang, Gabriela, Marin Meneses, Estefania, Cruise, Vanessa, Barraza, Ivana, Craddock, Travis J.A., Smith, Robert P.

“…Pseudomonas aeruginosa uses quorum sensing to regulate the expression of virulence factors. In static environments, spatial structures, such as biofilms, can…”
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Using gene expression signatures to identify novel treatment strategies in gulf war illness by Craddock, Travis J A, Harvey, Jeanna M, Nathanson, Lubov, Barnes, Zachary M, Klimas, Nancy G, Fletcher, Mary Ann, Broderick, Gordon

“…Gulf War Illness (GWI) is a complex multi-symptom disorder that affects up to one in three veterans of this 1991 conflict and for which no effective treatment…”
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Sleep restriction and delayed sleep associate with psychological health and biomarkers of stress and inflammation in women by Tartar, Jaime L., PhD, Fins, Ana I., PhD, Lopez, Andrea, MS, Sierra, Linett A., MS, Silverman, Sarah A., MS, Thomas, Samuel V., BS, Craddock, Travis J.A., PhD

“…Abstract Study objectives Despite strong associations between sleep duration and health, there is no clear understanding of how volitional chronic sleep…”
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Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction by Craddock, Travis J. A., Kurian, Philip, Preto, Jordane, Sahu, Kamlesh, Hameroff, Stuart R., Klobukowski, Mariusz, Tuszynski, Jack A.

“…Anesthesia blocks consciousness and memory while sparing non-conscious brain activities. While the exact mechanisms of anesthetic action are unknown, the…”
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Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status by Trivedi, Malav S, Holger, Dana, Bui, Anh Tuyet, Craddock, Travis J A, Tartar, Jaime L

“…Sleep is critical for repair as well as the rejuvenation processes in the body and many of these functions are regulated via underlying cellular metabolic…”
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Pharmaceutical Interventions in the Treatment of Chronic Fatigue Syndrome: A Literature-based Commentary by Richman, Spencer, Morris, Matthew C., Broderick, Gordon, Craddock, Travis J.A., Klimas, Nancy G., Fletcher, Mary Ann

“…Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disorder characterized by prolonged periods of fatigue, chronic pain, depression,…”
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Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary by Richman, Spencer, Morris, Matthew C., Broderick, Gordon, Craddock, Travis J.A., Klimas, Nancy G., Fletcher, Mary Ann

“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by prolonged periods of fatigue, chronic pain, depression,…”
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DRUGPATH: The Drug Gene Pathway Meta-Database by Jaundoo, Rajeev, Craddock, Travis J A

“…The complexity of modern-day diseases often requires drug treatment therapies consisting of multiple pharmaceutical interventions, which can lead to adverse…”
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A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activity by De Abreu, Isadora Rocha, Barkdull, Allison, Munoz, James R., Smith, Robert P., Craddock, Travis J. A.

“…Natural phenethylamines are trace amine neurotransmitters associated with dopamine transmission and related illnesses such Parkinson’s disease, and addiction…”
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The potential role of ocular and otolaryngological mucus proteins in myalgic encephalomyelitis/chronic fatigue syndrome by Huitsing, Kaylin, Tritsch, Tara, Arias, Francisco Javier Carrera, Collado, Fanny, Aenlle, Kristina K, Nathason, Lubov, Fletcher, Mary Ann, Klimas, Nancy G, Craddock, Travis J A

“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating illness associated with a constellation of other symptoms. While the most common…”
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Neuropsychological Findings in Gulf War Illness: A Review by Jeffrey, Mary G., Krengel, Maxine, Kibler, Jeffrey L., Zundel, Clara, Klimas, Nancy G., Sullivan, Kimberly, Craddock, Travis J. A.

“…This review paper summarizes the accumulation of research investigating neuropsychological outcomes in veterans with Gulf War illness (GWI). Earlier research…”
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The zinc dyshomeostasis hypothesis of Alzheimer's disease by Craddock, Travis J A, Tuszynski, Jack A, Chopra, Deepak, Casey, Noel, Goldstein, Lee E, Hameroff, Stuart R, Tanzi, Rudolph E

“…Alzheimer's disease (AD) is the most common form of dementia in the elderly. Hallmark AD neuropathology includes extracellular amyloid plaques composed largely…”
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Anesthetics act in quantum channels in brain microtubules to prevent consciousness by Craddock, Travis J A, Hameroff, Stuart R, Ayoub, Ahmed T, Klobukowski, Mariusz, Tuszynski, Jack A

“…The mechanism by which anesthetic gases selectively prevent consciousness and memory (sparing non-conscious brain functions) remains unknown. At the turn of…”
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High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology by Sedghamiz, Hooman, Morris, Matthew, Craddock, Travis J A, Whitley, Darrell, Broderick, Gordon

“…The hypothalamic-pituitary-adrenal (HPA) axis is a central regulator of stress response and its dysfunction has been associated with a broad range of complex…”
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Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome by Morris, Matthew C., Cooney, Katherine E., Sedghamiz, Hooman, Abreu, Maria, Collado, Fanny, Balbin, Elizabeth G., Craddock, Travis J.A., Klimas, Nancy G., Broderick, Gordon, Fletcher, Mary Ann

“…The complex and varied presentation of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has made it difficult to diagnose, study, and treat. Its…”
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Modeling Neuroimmune Interactions in Human Subjects and Animal Models to Predict Subtype-Specific Multidrug Treatments for Gulf War Illness by Carrera Arias, Francisco J., Aenlle, Kristina, Abreu, Maria, Holschbach, Mary A., Michalovicz, Lindsay T., Kelly, Kimberly A., Klimas, Nancy, O’Callaghan, James P., Craddock, Travis J. A.

“…Gulf War Illness (GWI) is a persistent chronic neuroinflammatory illness exacerbated by external stressors and characterized by fatigue, musculoskeletal pain,…”
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Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules by Jeffrey, Mary G., Nathanson, Lubov, Aenlle, Kristina, Barnes, Zachary M., Baig, Mirza, Broderick, Gordon, Klimas, Nancy G., Fletcher, Mary Ann, Craddock, Travis J.A.

“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisymptom illness impacting up to 1 million people in the United States. As…”
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