Search Results - "Cozzoli, Anna"

Gene expression in mdx mouse muscle in relation to age and exercise: aberrant mechanical-metabolic coupling and implications for pre-clinical studies in Duchenne muscular dystrophy by Camerino, Giulia Maria, Cannone, Maria, Giustino, Arcangela, Massari, Ada Maria, Capogrosso, Roberta Francesca, Cozzoli, Anna, De Luca, Annamaria

“…Weakness and fatigability are typical features of Duchenne muscular dystrophy patients and are aggravated in dystrophic mdx mice by chronic treadmill exercise…”
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Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse by Tinsley, Jonathon M, Fairclough, Rebecca J, Storer, Richard, Wilkes, Fraser J, Potter, Allyson C, Squire, Sarah E, Powell, Dave S, Cozzoli, Anna, Capogrosso, Roberta F, Lambert, Adam, Wilson, Francis X, Wren, Stephen P, De Luca, Annamaria, Davies, Kay E

“…Duchenne muscular dystrophy (DMD) is a lethal, progressive muscle wasting disease caused by a loss of sarcolemmal bound dystrophin, which results in the death…”
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Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice by Cozzoli, Anna, Nico, Beatrice, Sblendorio, Valeriana Teresa, Capogrosso, Roberta Francesca, Dinardo, Maria Maddalena, Longo, Vito, Gagliardi, Sara, Montagnani, Monica, De Luca, Annamaria

“…[Display omitted] ► An early treatment with enalapril was performed in exercised mdx mice. ► In vivo, enalapril increased mouse fore limb strength…”
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Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation by Camerino, Giulia Maria, Desaphy, Jean-François, De Bellis, Michela, Capogrosso, Roberta Francesca, Cozzoli, Anna, Dinardo, Maria Maddalena, Caloiero, Roberta, Musaraj, Kejla, Fonzino, Adriano, Conte, Elena, Jagerschmidt, Catherine, Namour, Florence, Liantonio, Antonella, De Luca, Annamaria, Conte Camerino, Diana, Pierno, Sabata

“…Muscle disuse produces severe atrophy and a slow-to-fast phenotype transition in the postural Soleus (Sol) muscle of rodents. Antioxidants, amino-acids and…”
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Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests by Burdi, Rosa, Rolland, Jean-Francois, Fraysse, Bodvael, Litvinova, Karina, Cozzoli, Anna, Giannuzzi, Viviana, Liantonio, Antonella, Camerino, Giulia Maria, Sblendorio, Valeriana, Capogrosso, Roberta Francesca, Palmieri, Beniamino, Andreetta, Francesca, Confalonieri, Paolo, De Benedictis, Leonarda, Montagnani, Monica, De Luca, Annamaria

“…1 Unit of Pharmacology, Department of Pharmaco-biology, Faculty of Pharmacy, University of Bari, Bari; 2 Department of General Surgery and Surgical…”
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Effects of prednisolone on the dystrophin-associated proteins in the blood–brain barrier and skeletal muscle of dystrophic mdx mice by Tamma, Roberto, Annese, Tiziana, Capogrosso, Roberta F, Cozzoli, Anna, Benagiano, Vincenzo, Sblendorio, Valeriana, Ruggieri, Simona, Crivellato, Enrico, Specchia, Giorgina, Ribatti, Domenico, De Luca, Annamaria, Nico, Beatrice

“…The mdx mouse, the most widely used animal model of Duchenne muscular dystrophy (DMD), develops a seriously impaired blood–brain barrier (BBB). As…”
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Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle by De Luca, Annamaria, Nico, Beatrice, Rolland, Jean-François, Cozzoli, Anna, Burdi, Rosa, Mangieri, Domenica, Giannuzzi, Viviana, Liantonio, Antonella, Cippone, Valentina, De Bellis, Michela, Nicchia, Grazia Paola, Camerino, Giulia Maria, Frigeri, Antonio, Svelto, Maria, Camerino, Diana Conte

“…Abstract Aminoglycosides force read through of premature stop codon mutations and introduce new mutation-specific gene-corrective strategies in Duchenne…”
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Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin‐deficient mdx mice: proof‐of‐concept study and independent validation of efficacy by Capogrosso, Roberta Francesca, Mantuano, Paola, Uaesoontrachoon, Kitipong, Cozzoli, Anna, Giustino, Arcangela, Dow, Todd, Srinivassane, Sadish, Filipovic, Marina, Bell, Christina, Vandermeulen, Jack, Massari, Ada Maria, De Bellis, Michela, Conte, Elena, Pierno, Sabata, Camerino, Giulia Maria, Liantonio, Antonella, Nagaraju, Kanneboyina, De Luca, Annamaria

“…Muscle fibers lacking dystrophin undergo a long‐term alteration of Ca2+ homeostasis, partially caused by aleaky Ca2+ release ryanodine (RyR) channel…”
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Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy by Mantuano, Paola, Sanarica, Francesca, Conte, Elena, Morgese, Maria Grazia, Capogrosso, Roberta Francesca, Cozzoli, Anna, Fonzino, Adriano, Quaranta, Angelo, Rolland, Jean-Francois, De Bellis, Michela, Camerino, Giulia Maria, Trabace, Luigia, De Luca, Annamaria

“…[Display omitted] The pharmacological stimulation of AMP-activated protein kinase (AMPK) via metabolic enhancers has been proposed as potential therapeutic…”
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Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points by Capogrosso, Roberta Francesca, Mantuano, Paola, Cozzoli, Anna, Sanarica, Francesca, Massari, Ada Maria, Conte, Elena, Fonzino, Adriano, Giustino, Arcangela, Rolland, Jean-Francois, Quaranta, Angelo, De Bellis, Michela, Camerino, Giulia Maria, Grange, Robert W, De Luca, Annamaria

“…Progressive weakness is a typical feature of Duchenne muscular dystrophy (DMD) patients and is exacerbated in the benign mdx mouse model by in vivo treadmill…”
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Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase by Cozzoli, Anna, Liantonio, Antonella, Conte, Elena, Cannone, Maria, Massari, Ada Maria, Giustino, Arcangela, Scaramuzzi, Antonia, Pierno, Sabata, Mantuano, Paola, Capogrosso, Roberta Francesca, Camerino, Giulia Maria, De Luca, Annamaria

“…Angiotensin II (ANG II) plays a role in muscle wasting and remodeling; however, little evidence shows its direct effects on specific muscle functions. We…”
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GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy by Cozzoli, Anna, Capogrosso, Roberta Francesca, Sblendorio, Valeriana Teresa, Dinardo, Maria Maddalena, Jagerschmidt, Catherine, Namour, Florence, Camerino, Giulia Maria, De Luca, Annamaria

“…Anabolic drugs may counteract muscle wasting and dysfunction in Duchenne muscular dystrophy (DMD); however, steroids have unwanted side effects. We focused on…”
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Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of duchenne muscular dystrophy: A comparison with the gold standard, α-methyl prednisolone by Capogrosso, Roberta Francesca, Cozzoli, Anna, Mantuano, Paola, Camerino, Giulia Maria, Massari, Ada Maria, Sblendorio, Valeriana Teresa, De Bellis, Michela, Tamma, Roberto, Giustino, Arcangela, Nico, Beatrice, Montagnani, Monica, De Luca, Annamaria

“…[Display omitted] Antioxidants have a great potential as adjuvant therapeutics in patients with Duchenne muscular dystrophy, although systematic comparisons at…”
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Disease-Related Modification of Chloride Conductance in Skeletal Muscle of Dystrophic Mice: Expression of CLC-1 Channel and Role of Inflammation and Oxidative Stress-Related Signaling by Camerino, Giulia M., Cozzoli, Anna, Capogrosso, Roberta F., Dinardo, Maria M., De Luca, Annamaria

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Skeletal Muscle Chloride Channel, a Biophysical Sensor of Dystrophic Progression in Mdx Mouse, is a Potential Target of Pro-inflammatory Mediators by Cozzoli, Anna, Pierno, Sabata, Camerino, Diana Conte, De Luca, Annamaria

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