Search Results - "Cozzi, P J"

PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways by Chang, L, Graham, P H, Hao, J, Ni, J, Bucci, J, Cozzi, P J, Kearsley, J H, Li, Y

“…The PI3K/Akt/mTOR pathway has a central role in cancer metastasis and radiotherapy. To develop effective therapeutics to improve radiosensitivity,…”
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Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance by Chang, L, Graham, P H, Hao, J, Ni, J, Bucci, J, Cozzi, P J, Kearsley, J H, Li, Y

“…Radioresistance is a major challenge in prostate cancer (CaP) radiotherapy (RT). In this study, we investigated the role and association of…”
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Intravesical oncolytic viral therapy using attenuated, replication‐competent, herpes simplex viruses G207 and Nv1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model by Cozzi, Paul J., Malhotra, Sandeep, McAuliffe, Priscilla, Kooby, David A., Federoff, Howard J., Huryk, Bob, Johnson, Paul, Scardino, Peter T., Heston, Warren D.W., Fong, Yuman

“…ABSTRACT Attenuated, replication‐competent herpes simplex virus mutants are attracting interest because of their ability to replicate within and kill tumor…”
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Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression by Hao, J, Chen, H, Madigan, M C, Cozzi, P J, Beretov, J, Xiao, W, Delprado, W J, Russell, P J, Li, Y

“…Background: The aim of this study is to seek an association between markers of metastatic potential, drug resistance-related protein and monocarboxylate…”
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Targeting uPA/uPAR in prostate cancer by Li, Y, Cozzi, P.J

“…Summary Prostate cancer (CaP) is one of the most common malignancies in men, with an increasing incidence. Despite significant advances in surgery,…”
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Immunohistochemical characterisation of the monoclonal antibody BLCA-38 for the detection of prostate cancer by RUSSELL, P. J, OW, K. T, TAM, P. N, JUAREZ, J, KINGSLEY, E. A, QU, C. F, LI, Y, COZZI, P. J, MARTINIELLO-WILKS, R

“…Monoclonal antibodies (MAbs) can be used to detect, image and treat cancers. This study aimed to characterise the binding of BLCA-38 MAbs to human prostate…”
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Cryotherapy treatment of patients with hepatic metastases from neuroendocrine tumors by Cozzi, P J, Englund, R, Morris, D L

“…Liver metastases from neuroendocrine tumors often present with disabling symptoms due to syndromes of hormonal excess. A locally destructive technique such as…”
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MUC1 is a promising therapeutic target for prostate cancer therapy by Li, Y, Cozzi, P J

“…Prostate cancer (CaP) is one of the most common malignancies in men, and the incidence of CaP is increasing. Because of the limitations of current therapeutic…”
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CD147/EMMPRIN and CD44 are potential therapeutic targets for metastatic prostate cancer by Hao, J L, Cozzi, P J, Khatri, A, Power, C A, Li, Y

“…Prostate cancer (CaP) is a major health problem in males in Western countries. Current therapeutic approaches are limited and many patients die of secondary…”
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Toxicology and Pharmacokinetics of Intravesical Gemcitabine: A Preclinical Study in Dogs by COZZI, P. J, BAJORIN, D. F, TONG, W, NGUYEN, H, SCOTT, J, HESTON, W. D. W, DALBAGNI, G

“…More active and well-tolerated agents are needed for the treatment of superficial bladder cancer. This study investigated intravesical gemcitabine to establish…”
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Cyclophosphamide in the treatment of pulmonary diseases: survey of use, training, and practitioner knowledge base by Cozzi, P J, Hall, J B

“…To assess pulmonologists' use, training in the use, and knowledge base of the drug cyclophosphamide. Survey through questionnaire. Testing of knowledge base…”
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Pulmonary artery diastolic-occlusion pressure gradient is increased in acute pulmonary embolism by Cozzi, Phillip J, Hall, Jesse B, Schmidt, Gregory A

“…OBJECTIVE To assess the pulmonary artery (PA) diastolic-occlusion (wedge) pressure gradient in patients with acute pulmonary embolism and to evaluate this…”
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Two Cases of Spontaneous Liver Rupture and Literature Review by Cozzi, P J, Morris, D L

“…Spontaneous liver rupture is uncommon, difficult to diagnose and carries a universally high mortality. It has been well documented to occur as a complication…”
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Airway compression by a mediastinal mass by Cozzi, P J, Schmidt, G A

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Activation of tracheal smooth muscle responsiveness by fMLP-treated HL-60 cells and neutrophils by Munoz, N M, Hamann, K J, Vita, A, Cozzi, P J, Baranowski, S, Solway, J, Leff, A R

“…We assessed the effects of cultured human promyelocytic leukemia (HL-60) cells and polymorphonuclear leukocytes (neutrophils) isolated from peripheral human…”
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Laparoscopic vs Open Ultrasound of the Liver: An in vitro Study by Cozzi, P J, McCall, J L, Jorgensen, J O, Morris, D L

“…Intra-operative contact ultrasound is a sensitive method of detecting liver tumours. The aim of this study was to compare the sensitivity of open contact…”
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Amyloidosis in Association with Human Immunodeficiency Virus Infection by Cozzi, Phillip J., Abu-Jawdeh, Graziella M., Green, Richard M., Green, David

“…Amyloidosis has not been previously reported in association with human immunodeficiency virus (HIV) infection. An HIV-infected patient with hemophilia who…”
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In vitro and in vivo assessment of urethral warming catheters for the transperineal cryoablation of prostatic carcinoma by Cozzi, P J, Lynch, W J, Robson, N, Vonthethoff, L, Lumley, T, Morris, D L

“…To evaluate the two most common urethral warming catheters currently available for their effectiveness in preventing urethral injury in an animal model and…”
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Critical temperature for in vivo cryoablation of human prostate cancer in a xenograft model by Cozzi, P J, Lawson, J A, Lynch, W J, Morris, D L

“…To assess the in vivo sensitivity of human prostate cancer cells (PC3) to cryoablation and thus define the minimum temperature needed to prevent the recurrence…”
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Sequence and functional characterization of feline interleukin 2 by Cozzi, P J, Padrid, P A, Takeda, J, Alegre, M L, Yuhki, N, Leff, A R

“…Since the discovery of its involvement in the pathogenesis of feline immunodeficiency virus infection ("cat AIDS") and feline leukemia virus infection, the…”
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