Search Results - "Coyte, Katharine Z."
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Understanding Competition and Cooperation within the Mammalian Gut Microbiome
Published in Current biology (03-06-2019)“…The mammalian gut harbors a vast community of microorganisms — termed the microbiota — whose composition and dynamics are considered to be critical drivers of…”
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The ecology of the microbiome: Networks, competition, and stability
Published in Science (American Association for the Advancement of Science) (06-11-2015)“…The human gut harbors a large and complex community of beneficial microbes that remain stable over long periods. This stability is considered critical for good…”
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The evolution of the host microbiome as an ecosystem on a leash
Published in Nature (London) (03-08-2017)“…The human body carries vast communities of microbes that provide many benefits. Our microbiome is complex and challenging to understand, but evolutionary…”
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Multi-kingdom ecological drivers of microbiota assembly in preterm infants
Published in Nature (London) (25-03-2021)“…The gut microbiota of preterm infants develops predictably 1 – 7 , with pioneer species colonizing the gut after birth, followed by an ordered succession of…”
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Ecological rules for the assembly of microbiome communities
Published in PLoS biology (19-02-2021)“…Humans and many other hosts establish a diverse community of beneficial microbes anew each generation. The order and identity of incoming symbionts is critical…”
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Reactivity of complex communities can be more important than stability
Published in Nature communications (08-11-2023)“…Understanding stability—whether a community will eventually return to its original state after a perturbation—is a major focus in the study of various complex…”
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Horizontal gene transfer and ecological interactions jointly control microbiome stability
Published in PLoS biology (09-11-2022)“…Genes encoding resistance to stressors, such as antibiotics or environmental pollutants, are widespread across microbiomes, often encoded on mobile genetic…”
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Microbial competition in porous environments can select against rapid biofilm growth
Published in Proceedings of the National Academy of Sciences - PNAS (10-01-2017)“…Microbes often live in dense communities called biofilms, where competition between strains and species is fundamental to both evolution and community…”
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Microbial communities as dynamical systems
Published in Current opinion in microbiology (01-08-2018)“…[Display omitted] •Ordination plots visualize movement through community space.•Generalized Lotka–Volterra (gLV) model predicts stability and responses to…”
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When microbes go missing: Understanding the impact of diversity loss within the gut microbiome
Published in Cell host & microbe (09-08-2023)“…Two recent papers published in Cell highlight the power of both top-down and bottom-up approaches to understanding the gut microbiome. The first uses…”
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Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite
Published in Cell (03-02-2022)“…The human gut microbiota resides within a diverse chemical environment challenging our ability to understand the forces shaping this ecosystem. Here, we reveal…”
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Time delays modulate the stability of complex ecosystems
Published in Nature ecology & evolution (01-10-2023)“…What drives the stability, or instability, of complex ecosystems? This question sits at the heart of community ecology and has motivated a large body of…”
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Understanding the development and function of the gut microbiota in health and inflammation
Published in Frontline gastroenterology (01-08-2022)“…The gut microbiota is known to play an important role in maintaining gut health through a symbiotic relationship with the host. Altered gut microbiota is a…”
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Journal Article Book Review -
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REPLY TO BAVEYE AND DARNAULT: Useful models are simple and extendable
Published in Proceedings of the National Academy of Sciences - PNAS (04-04-2017)“…Baveye and Darnault (2) contend that our model (3) is too simple and that we should have considered more intricate biofilm distributions and other microbes…”
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The Impact of Peri-Transplant Antibiotic Exposure on Outcomes in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Published in Biology of blood and marrow transplantation (01-03-2020)“…Survival after allogeneic hematopoietic stem cell transplantation (ASCT) has significantly improved with early recognition of sepsis and prompt empiric…”
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