Search Results - "Coyne, Sebastien"
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Acquisition of multidrug resistance transposon Tn6061 and IS6100-mediated large chromosomal inversions in Pseudomonas aeruginosa clinical isolates
Published in Microbiology (Society for General Microbiology) (01-05-2010)“…Pseudomonas aeruginosa is a major human opportunistic pathogen, especially for patients in intensive care units or with cystic fibrosis. Multidrug resistance…”
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Biosynthesis of the Antimetabolite 6-Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis
Published in Angewandte Chemie International Edition (27-09-2013)“…Sulfur for fire: The molecular basis for the biosynthesis of the antimetabolite 6‐thioguanine (6TG) was unveiled in Erwinia amylovora, the causative agent of…”
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Efflux-Mediated Antibiotic Resistance in Acinetobacter spp
Published in Antimicrobial Agents and Chemotherapy (01-03-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens
Published in Microbiology spectrum (15-06-2023)“…After the first total synthesis combined with structure revision, we performed thorough and profiling of the underexplored tetrapeptide GE81112A. From the…”
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Overexpression of Resistance-Nodulation-Cell Division Pump AdeFGH Confers Multidrug Resistance in Acinetobacter baumannii
Published in Antimicrobial Agents and Chemotherapy (01-10-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Control of Plant Defense Mechanisms and Fire Blight Pathogenesis through the Regulation of 6-Thioguanine Biosynthesis in Erwinia amylovora
Published in Chembiochem : a European journal of chemical biology (10-02-2014)“…Fire blight is a devastating disease of Rosaceae plants, such as apple and pear trees. It is characterized by necrosis of plant tissue, caused by the…”
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Origin and evolution of antibiotic resistance: the common mechanisms of emergence and spread in water bodies
Published in Frontiers in microbiology (01-01-2012)“…The environment, and especially freshwater, constitutes a reactor where the evolution and the rise of new resistances occur. In water bodies such as waste…”
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Screening and Quantification of the Expression of Antibiotic Resistance Genes in Acinetobacter baumannii with a Microarray
Published in Antimicrobial Agents and Chemotherapy (01-01-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antibiotics from neglected bacterial sources
Published in International journal of medical microbiology (01-01-2014)“…Abstract The current crop of antibiotics in clinical use are either natural products or their derivatives. However, the rise of a multitude of different…”
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Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway
Published in Angewandte Chemie International Edition (03-09-2018)“…6‐Thioguanine (6TG) is a DNA‐targeting therapeutic used in the treatment of various cancers. While 6TG was rationally designed as a proof of concept for…”
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Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
Published in European journal of medicinal chemistry (05-02-2024)“…Tridecaptins comprise a class of linear cationic lipopeptides with an N-terminal fatty acyl moiety. These 13-mer antimicrobial peptides consist of a…”
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Cover Picture: Biosynthesis of the Antimetabolite 6-Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis (Angew. Chem. Int. Ed. 40/2013)
Published in Angewandte Chemie International Edition (27-09-2013)“…Sulfur for fire: The molecular basis for the biosynthesis of the antimetabolite 6-thioguanine (6TG) was unveiled in Erwinia amylovora, the causative agent of…”
Get full text
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Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway
Published in Angewandte Chemie (03-09-2018)“…6‐Thioguanine (6TG) is a DNA‐targeting therapeutic used in the treatment of various cancers. While 6TG was rationally designed as a proof of concept for…”
Get full text
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Biosynthesis of the Antimetabolite 6-Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis
Published in Angewandte Chemie (27-09-2013)“…Schwefel und Feuerbrand: Die molekularen Grundlagen der Biosynthese des Antimetaboliten 6‐Thioguanin (6TG) wurden in dem Feuerbrand verursachenden Bakterium…”
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Biosynthesis of the Antimetabolite 6‐Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis
Published in Angewandte Chemie (27-09-2013)Get full text
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