Search Results - "Coyne, P"

Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics by Wedley, Amy L., Dawson, Susan, Maddox, Thomas W., Coyne, Karen P., Pinchbeck, Gina L., Clegg, Peter, Nuttall, Tim, Kirchner, Miranda, Williams, Nicola J.

“…•Antimicrobial resistant (AMR) E. coli from faeces of vet-visiting dogs were common.•Risk factors for carriage include antimicrobial use and consuming raw…”
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Carnosic Acid, Tangeretin, and Ginkgolide-B Anti-neoplastic Cytotoxicity in Dual Combination with Dexamethasone-[anti-EGFR] in Pulmonary Adenocarcinoma (A549) by Coyne, Cody P, Narayanan, Lakshmi

“…Traditional chemotherapeutics of low-molecular weight diffuse passively across intact membrane structures of normal healthy cells found in tissues and organ…”
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Mitochondrial protein import clogging as a mechanism of disease by Coyne, Liam P, Wang, Xiaowen, Song, Jiyao, de Jong, Ebbing, Schneider, Karin, Massa, Paul T, Middleton, Frank A, Becker, Thomas, Chen, Xin Jie

“…Mitochondrial biogenesis requires the import of >1,000 mitochondrial preproteins from the cytosol. Most studies on mitochondrial protein import are focused on…”
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A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and RTS,S formulated with AS02 adjuvant in healthy, malaria-naïve adults by Cummings, J.F., Polhemus, M.E., Kester, K.E., Ockenhouse, C.F., Gasser, R.A., Coyne, P., Wortmann, G., Nielsen, R.K., Schaecher, K., Holland, C.A., Krzych, U., Tornieporth, N., Soisson, L.A., Angov, E., Heppner, D.G.

“…To improve the efficacy of Plasmodium falciparum malaria vaccine RTS,S/AS02, we conducted a study in 2001 in healthy, malaria-naïve adults administered…”
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Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial by Harji, D P, Marshall, H, Gordon, K, Twiddy, M, Pullan, A, Meads, D, Croft, J, Burke, D, Griffiths, B, Verjee, A, Sagar, P, Stocken, D, Brown, J, Baker, R, Berger, C, Cardozo, W, Chapman, S, Codd, R, Coyne, P, Davies, J, Evans, M, Harries, D, Harries, R, Hicks, L, Jayamanne, H, Kelly, S, Lockwood, S, Madhavan, A, McCallum, I, Moriarty, C, Nassa, H, Plusa, S, Priestley, M, Scott, J, Stephenson, S, Swarnkar, K, Taylor, G, White, L, Williams, G, Williams, M

“…Abstract Background Approximately 30 000 people undergo major emergency abdominal gastrointestinal surgery annually, and 36 per cent of these procedures…”
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The impact of multidisciplinary team decision-making in locally advanced and recurrent rectal cancer by Harji, D P, Houston, F, Cutforth, I, Hawthornthwaite, E, McKigney, N, Sharpe, A, Coyne, P, Griffiths, B

“…Appropriate patient selection within the context of a multidisciplinary team (MDT) is key to good clinical outcomes. The current evidence base for factors that…”
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Large-Scale Spatial and Temporal Genetic Diversity of Feline Calicivirus by COYNE, Karen P, CHRISTLEY, Rob M, PYBUS, Oliver G, DAWSON, Susan, GASKELL, Rosalind M, RADFORD, Alan D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Canine parvovirus in asymptomatic feline carriers by Clegg, S.R., Coyne, K.P., Dawson, S., Spibey, N., Gaskell, R.M., Radford, A.D.

“…Canine parvovirus (CPV) and feline panleukopaenia virus (FPLV) are two closely related viruses, which are known to cause severe disease in younger unvaccinated…”
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Molecular Epidemiology and Phylogeny Reveal Complex Spatial Dynamics in Areas Where Canine Parvovirus Is Endemic by CLEGG, S. R, COYNE, K. P, PARKER, J, DAWSON, S, GODSALL, S. A, PINCHBECK, G, CRIPPS, P. J, GASKELL, R. M, RADFORD, A. D

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Practical guidelines for developing new palliative care services: resource management by Smith, T J, Coyne, P J, Cassel, J B

“…The data are relatively clear cut that palliative care improves quality of life and symptom control, improves quality of care by reducing aggressive but…”
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Contemporary smartphone and social media resources for patients with anal cancer: an unmet need by Platt, J. R., Nawaz, U., Coyne, P., Griffiths, B., Brady, R. R. W.

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The association between dog ownership or dog walking and fitness or weight status in childhood by Westgarth, C., Boddy, L. M., Stratton, G., German, A. J., Gaskell, R. M., Coyne, K. P., Bundred, P., McCune, S., Dawson, S.

“…Summary Background Health benefits of dog walking are established in adults: dog owners are on average more physically active, and those walking their dogs…”
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TREATMENT-RESISTANT EPILEPSY AND TREATMENT-RESISTANT SCHIZOPHRENIA; A REAL CHALLENGE FOR THE PSYCHIATRIC TEAM by Zubair, Usama Bin, Breen, Eugene G, Zubair, Hamza Bin, Elhassan, Haytham, Coyne, Cathal P, Khair, Ibtihal

“…Schizophrenia and epilepsy may exist together, but it is very rare to have a resistant form of both illnesses in one patient. We present a case report of a…”
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An implantable drug delivery system (IDDS) for refractory cancer pain provides sustained pain control, less drug-related toxicity, and possibly better survival compared with comprehensive medical management (CMM) by Smith, T. J., Coyne, P. J., Staats, P. S., Deer, T., Stearns, L. J., Rauck, R. L., Boortz-Marx, R. L., Buchser, E., Català, E., Bryce, D. A., Cousins, M., Pool, G. E.

“…Background:: The randomized clinical trial of implantable drug delivery systems (IDDS) plus comprehensive medical management (CMM) versus CMM alone showed…”
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Family pet ownership during childhood: findings from a UK birth cohort and implications for public health research by Westgarth, Carri, Heron, Jon, Ness, Andy R, Bundred, Peter, Gaskell, Rosalind M, Coyne, Karen P, German, Alexander J, McCune, Sandra, Dawson, Susan

“…In developed nations, approximately half of household environments contain pets. Studies of Human-Animal Interaction (HAI) have proposed that there are health…”
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Dexamethasone-(C21-phosphoramide)-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549) by Coyne, Cody P, Narayanan, Lakshmi

“…Corticosteroids are effective in the management of a variety of disease states, such as several forms of neoplasia (leukemia and lymphoma), autoimmune…”
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Evolutionary Mechanisms of Persistence and Diversification of a Calicivirus within Endemically Infected Natural Host Populations by COYNE, Karen P, GASKELL, Rosalind M, DAWSON, Susan, PORTER, Carol J, RADFORD, Alan D

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mPOS is a novel mitochondrial trigger of cell death – implications for neurodegeneration by Coyne, Liam P., Chen, Xin Jie

“…In addition to its central role in energy metabolism, the mitochondrion has many other functions essential for cell survival. When stressed, the…”
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Multilocus Sequence Typing of Bartonella henselae in the United Kingdom Indicates that Only a Few, Uncommon Sequence Types Are Associated with Zoonotic Disease by CHALONER, Gemma L, HARRISON, Timothy G, COYNE, Karen P, AANENSEN, David M, BIRTLES, Richard J

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Anti-neoplastic cytotoxicity by complementary simultaneous selective “targeted” delivery for pulmonary adenocarcinoma: fludarabine-(5′-phosphoramidate)-[anti-IGF-1R] in dual-combination with dexamethasone-(C21-phosphoramidate)-[anti-EGFR] by Coyne, Cody P., Narayanan, Lakshmi

“…Selective “targeted” delivery of chemotherapeutic agents represents a molecular strategy for achieving enhanced margins-of-safety and greater potency compared…”
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