Search Results - "Coyle, E."

Social Isolation, Loneliness and Health Among Older Adults by Coyle, Caitlin E., Dugan, Elizabeth

“…Objective: To examine the relationship of social isolation, loneliness and health outcomes among older adults. Methods: Using data from the Leave Behind…”
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Leveraging the Social Determinants of Health: What Works? by Taylor, Lauren A, Tan, Annabel Xulin, Coyle, Caitlin E, Ndumele, Chima, Rogan, Erika, Canavan, Maureen, Curry, Leslie A, Bradley, Elizabeth H

“…We summarized the recently published, peer-reviewed literature that examined the impact of investments in social services or investments in integrated models…”
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Serine is a natural ligand and allosteric activator of pyruvate kinase M2 by Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal

“…The M2 isoform of pyruvate kinase (PKM2) is a key glycolytic enzyme that is overexpressed in cancer cells; here, serine is shown to bind to and directly…”
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Breaking the Ring through a Room Temperature Catalytic Wittig Reaction by O'Brien, Christopher J., Lavigne, Florie, Coyle, Emma E., Holohan, Andrew J., Doonan, Bryan J.

“…One ring no longer rules them all: Employment of 2.5–10 mol % of 4‐nitrobenzoic acid with phenylsilane led to the development of a room temperature catalytic…”
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Catalytic Wittig Reactions of Semi- and Nonstabilized Ylides Enabled by Ylide Tuning by Coyle, Emma E., Doonan, Bryan J., Holohan, Andrew J., Walsh, Killian A., Lavigne, Florie, Krenske, Elizabeth H., O'Brien, Christopher J.

“…The first examples of catalytic Wittig reactions with semistabilized and nonstabilized ylides are reported. These reactions were enabled by utilization of a…”
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The effects of fasting on metabolism and performance by Maughan, R J, Fallah, J, Coyle, E F

“…An overnight fast of 8-10 h is normal for most people. Fasting is characterised by a coordinated set of metabolic changes designed to spare carbohydrate and…”
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Microarray analysis of rat sensory ganglia after local inflammation implicates novel cytokines in pain by Strong, Judith A, Xie, Wenrui, Coyle, Dennis E, Zhang, Jun-Ming

“…Inflammation plays a role in neuropathic pain conditions as well as in pain induced solely by an inflammatory stimulus. Robust mechanical hyperalgesia and…”
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Substorms and Solar Eclipses: A Mutual Information Based Study by Coyle, S. E., Baker, J. B. H., Chakraborty, S., Hartinger, M. D., Freeman, M. P., Clauer, C. R., Xu, Z., Weimer, D. R.

“…Solar eclipses present a rare glimpse into the impact of ionospheric electrodynamics on the magnetosphere independent of other well studied seasonal…”
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Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design by Woodhead, Andrew J, Angove, Hayley, Carr, Maria G, Chessari, Gianni, Congreve, Miles, Coyle, Joseph E, Cosme, Jose, Graham, Brent, Day, Philip J, Downham, Robert, Fazal, Lynsey, Feltell, Ruth, Figueroa, Eva, Frederickson, Martyn, Lewis, Jonathan, McMenamin, Rachel, Murray, Christopher W, O’Brien, M. Alistair, Parra, Lina, Patel, Sahil, Phillips, Theresa, Rees, David C, Rich, Sharna, Smith, Donna-Michelle, Trewartha, Gary, Vinkovic, Mladen, Williams, Brian, Woolford, Alison J.-A

“…Inhibitors of the molecular chaperone heat shock protein 90 (Hsp90) are currently generating significant interest in clinical development as potential…”
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Part I: The Development of the Catalytic Wittig Reaction by O'Brien, Christopher J., Nixon, Zachary S., Holohan, Andrew J., Kunkel, Stephen R., Tellez, Jennifer L., Doonan, Bryan J., Coyle, Emma E., Lavigne, Florie, Kang, Lauren J., Przeworski, Katherine C.

“…We have developed the first catalytic (in phosphane) Wittig reaction (CWR). The utilization of an organosilane was pivotal for success as it allowed for the…”
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Self-management activities in diabetes care: A systematic review by Coyle, Meaghan E, Francis, Karen, Chapman, Ysanne

“…Objective. To identify the range of self-management activities people diagnosed with diabetes engage in to manage their disease, the frequency of use, and…”
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Crystal structure of human CDK4 in complex with a D-type cyclin by Day, Philip J, Cleasby, Anne, Tickle, Ian J, O'Reilly, Marc, Coyle, Joe E, Holding, Finn P, McMenamin, Rachel L, Yon, Jeff, Chopra, Rajiv, Lengauer, Christoph, Jhoti, Harren

“…The cyclin D1-cyclin-dependent kinase 4 (CDK4) complex is a key regulator of the transition through the G₁ phase of the cell cycle. Among the cyclin/CDKs, CDK4…”
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A Delphi Study of Expert Consensus on Chinese Medicine Syndrome Differentiation and Herbal Use for Early Breast Cancer by Guo, Qianqian, Zhang, Anthony Lin, Xue, Charlie Changli, Coyle, Meaghan E., Chen, Qianjun

“…Objectives: Chinese herbal medicine (CHM) is widely used in breast cancer, but there is no consensus on the Chinese medicine (CM) syndromes in the different…”
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Acupuncture and moxibustion for endometriosis: A systematic review and analysis by Wang, Yongxia, Coyle, Meaghan E., Hong, Miaowen, He, Siya, Zhang, Anthony L., Guo, Xinfeng, Lu, Chuanjian, Xue, Charlie C.L., Liang, Xuefang

“…This study aimed to examine the effect of acupuncture on symptoms and health-related quality of life in patients with endometriosis. Nine biomedical databases…”
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Multi-directional electrodeposited gold nanospikes for antibacterial surface applications by Elbourne, Aaron, Coyle, Victoria E., Truong, Vi Khanh, Sabri, Ylias M., Kandjani, Ahmad E., Bhargava, Suresh K., Ivanova, Elena P., Crawford, Russell J.

“…The incorporation of high-aspect-ratio nanostructures across surfaces has been widely reported to impart antibacterial characteristics to a substratum. This…”
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Higher throughput calorimetry: opportunities, approaches and challenges by Torres, Francisco E, Recht, Michael I, Coyle, Joseph E, Bruce, Richard H, Williams, Glyn

“…Higher throughput thermodynamic measurements can provide value in structure-based drug discovery during fragment screening, hit validation, and lead…”
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Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons by Coyle, Dennis E, Li, Jie, Baccei, Mark

“…The NTERA2 cl D1 (NT2) cell line, derived from human teratocarcinoma, exhibits similar properties as embryonic stem (ES) cells or very early neuroepithelial…”
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Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior by Coyle, Dennis E.

“…Three different cell markers were studied in rats to note changes in the immunoreactivity (IR) in the lumbar spinal cord 1 to 84 days following partial sciatic…”
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Superlative and Selective Sensing of Serotonin in Undiluted Human Serum Using Novel Polystyrene Sulfonate Conductive Polymer by Coyle, Victoria E., Brothers, Michael C., McDonald, Sarah, Kim, Steve S.

“…In the past 5 years, real-time health monitoring has become ubiquitous with the development of watches and rings that can measure and report on the…”
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Cephalic version by moxibustion for breech presentation by Coyle, Meaghan E, Smith, Caroline, Peat, Brian

“…Breech presentation at term can cause complications during birth and increase the chance of caesarean section. Moxibustion (a type of Chinese medicine which…”
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