Search Results - "Coyle, Chris"
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Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons
Published in Journal of neuroendocrinology (01-04-2022)“…Polycystic ovary syndrome (PCOS) is associated with androgen excess and, frequently, hyperactive pulsatile luteinizing hormone (LH) secretion. Although the…”
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Prospective Stage-Stratified Approach to AIDS-Related Kaposi's Sarcoma
Published in Journal of clinical oncology (10-02-2014)“…Combination antiretroviral therapy (cART) is standard of care for patients with HIV diagnosed with Kaposi's sarcoma (KS), but the current role of systemic…”
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Cyclical DNA Methyltransferase 3a Expression Is a Seasonal and Estrus Timer in Reproductive Tissues
Published in Endocrinology (Philadelphia) (01-06-2016)“…It is becoming clear that epigenetic modifications such as DNA methylation can be dynamic and, in many cases, reversible. Here we investigated the photoperiod…”
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Ovarian hormones induce de novo DNA methyltransferase expression in the Siberian hamster suprachiasmatic nucleus
Published in Journal of neuroendocrinology (01-02-2020)“…The present study investigated neuroanatomically localised changes in de novo DNA methyltransferase expression in the female Siberian hamster (Phodopus…”
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Effects of temperature and pressure on the performance of a solid oxide fuel cell running on steam reformate of kerosene
Published in Journal of power sources (15-08-2013)“…A button solid oxide fuel cell with a La0.6Sr0.4Co0.2Fe0.8O3 cathode and a nickel-YSZ anode was tested over a range of temperatures from 650 to 800 °C and a…”
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The sexual scripts of Kenyan young people and HIV prevention
Published in Culture, health & sexuality (01-01-2005)“…The scripting of sexual encounters among young people in Kenyan is described using results of 28 focus group discussions conducted with young people attending…”
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Rupture Testing as a Tool for Developing Planar Solid Oxide Fuel Cell Seals
Published in Journal of materials engineering and performance (01-06-2004)“…One of the critical issues in designing and fabricating high-performance planar solid oxide fuel cell (pSOFC) stacks is the ability to hermetically seal…”
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A high-performance intermediate temperature reversible solid oxide cell with a new barrier layer free oxygen electrode
Published in Applied energy (01-05-2024)“…The best solution to address the critical durability issue of solid oxide electrolytic cells (SOECs) for high-efficiency and high-rate H2 production is to…”
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Investigating GABA Neuron–Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS
Published in Endocrinology (Philadelphia) (27-05-2024)“…Abstract Androgen excess is a hallmark feature of polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Clinical and preclinical…”
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Effects of trace metals and organic additives on porosity and dielectric constant of high purity mesoporous silica films
Published in Chemical communications (Cambridge, England) (07-08-2003)“…The beneficial effects that alkali metal and alkylammonium salt additions to molecularly templated silica sols have on the resulting mesoporous silica films…”
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Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome
Published in EBioMedicine (01-06-2019)“…Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the most common…”
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Chronic Excess of Non-Aromatizable Androgens From Puberty Does Not Drive a Neuroendocrine Phenotype Observed in Other Preclinical Rodent Models of PCOS
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Polycystic ovary syndrome (PCOS) is the most common form of anovulatory infertility in women of reproductive age, characterised by androgen excess,…”
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PROMIS — Prostate MR imaging study: A paired validating cohort study evaluating the role of multi-parametric MRI in men with clinical suspicion of prostate cancer
Published in Contemporary clinical trials (01-05-2015)“…Abstract Background Transrectal ultrasound-guided prostate biopsies are prone to detection errors. Multi-parametric MRI (MP-MRI) may improve the diagnostic…”
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Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndromeResearch in context
Published in EBioMedicine (01-06-2019)“…Background: Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the…”
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The effectiveness of community interventions targeting HIV and AIDS prevention at young people in developing countries
Published in World Health Organization technical report series (2006)“…To identify successful HIV/AIDS prevention interventions targeting youths and delivered in geographically bounded communities (for example, rural villages,…”
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Phase Transitions and Transient Liquid-Phase Sintering in Calcium-Substituted Lanthanum Chromite
Published in Journal of the American Ceramic Society (01-08-1997)“…This paper investigates sintering and phase transitions of La0.7CaxCrO3(0.25≥x≥0.35), a material useful as electrical interconnections in solid oxide fuel…”
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Multiple voices in HIV and AIDS: A comparison of the discourses of Christian religion and public health
Published 2004“…Concern over the devastating effects of HIV and AIDS in Africa has inspired many organizations to develop intervention programmes that aim to reduce the impact…”
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Dissertation -
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Extending HIV/AIDS-Prevention Efforts in Kenya: Primary Schools as Community-Based Organizations
Published in Environment and planning. C, Government & policy (01-06-2007)“…The question of whether primary schools in Kenya can take on community-based activities beyond their day-to-day functioning, emerged from a larger HIV/AIDS…”
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