Search Results - "Coyan, Fabien C"

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  1. 1

    Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism by Malak, Olfat A., Abderemane-Ali, Fayal, Wei, Yue, Coyan, Fabien C., Pontus, Gilyane, Shaya, David, Marionneau, Céline, Loussouarn, Gildas

    Published in Scientific reports (03-04-2020)
    “…Prokaryotic Na V channels are tetramers and eukaryotic Na V channels consist of a single subunit containing four domains. Each monomer/domain contains six…”
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    Journal Article
  2. 2

    A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation by Coyan, Fabien C, Abderemane-Ali, Fayal, Amarouch, Mohamed Yassine, Piron, Julien, Mordel, Jérôme, Nicolas, Céline S, Steenman, Marja, Mérot, Jean, Marionneau, Céline, Thomas, Annick, Brasseur, Robert, Baró, Isabelle, Loussouarn, Gildas

    Published in PloS one (28-03-2014)
    “…Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor necessary for the activity of KCNQ1 channels. Some Long QT mutations of KCNQ1, including R243H,…”
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    Journal Article
  3. 3

    C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation by Burel, Sophie, Coyan, Fabien C., Lorenzini, Maxime, Meyer, Matthew R., Lichti, Cheryl F., Brown, Joan H., Loussouarn, Gildas, Charpentier, Flavien, Nerbonne, Jeanne M., Townsend, R. Reid, Maier, Lars S., Marionneau, Céline

    Published in The Journal of biological chemistry (20-10-2017)
    “…Voltage-gated Na+ (NaV) channels are key regulators of myocardial excitability, and Ca2+/calmodulin-dependent protein kinase II (CaMKII)-dependent alterations…”
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    Journal Article
  4. 4

    C-terminal phosphorylation of Na V 1.5 impairs FGF13-dependent regulation of channel inactivation by Burel, Sophie, Coyan, Fabien C, Lorenzini, Maxime, Meyer, Matthew R, Lichti, Cheryl F, Brown, Joan H, Loussouarn, Gildas, Charpentier, Flavien, Nerbonne, Jeanne M, Townsend, R Reid, Maier, Lars S, Marionneau, Céline

    Published in The Journal of biological chemistry (20-10-2017)
    “…Voltage-gated Na (Na ) channels are key regulators of myocardial excitability, and Ca /calmodulin-dependent protein kinase II (CaMKII)-dependent alterations in…”
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    Journal Article
  5. 5
  6. 6

    Opposite Effects of the S4–S5 Linker and PIP2 on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels by Choveau, Frank S., Abderemane-Ali, Fayal, Coyan, Fabien C., Es-Salah-Lamoureux, Zeineb, Baró, Isabelle, Loussouarn, Gildas

    Published in Frontiers in pharmacology (2012)
    “…Voltage-gated potassium (Kv) channels are tetramers, each subunit presenting six transmembrane segments (S1–S6), with each S1–S4 segments forming a…”
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    Journal Article
  7. 7
  8. 8

    A Long QT Mutation Substitutes Cholesterol for Phosphatidylinositol-4,5-Bisphosphate in KCNQ1 Channel Regulation: e93255 by Coyan, Fabien C, Abderemane-Ali, Fayal, Amarouch, Mohamed Yassine, Piron, Julien, Mordel, Jerome, Nicolas, Celine S, Steenman, Marja, Merot, Jean, Marionneau, Celine, Thomas, Annick

    Published in PloS one (01-03-2014)
    “…Introduction Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor necessary for the activity of KCNQ1 channels. Some Long QT mutations of KCNQ1,…”
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    Journal Article
  9. 9

    Opposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels by Choveau, Frank S, Abderemane-Ali, Fayal, Coyan, Fabien C, Es-Salah-Lamoureux, Zeineb, Baró, Isabelle, Loussouarn, Gildas

    Published in Frontiers in pharmacology (2012)
    “…Voltage-gated potassium (Kv) channels are tetramers, each subunit presenting six transmembrane segments (S1-S6), with each S1-S4 segments forming a…”
    Get full text
    Journal Article