Search Results - "Coxson, Harvey O"
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CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society
Published in Radiology (01-10-2015)“…The purpose of this statement is to describe and define the phenotypic abnormalities that can be identified on visual and quantitative evaluation of computed…”
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2
Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-04-2016)“…After adjustment for the amount of smoking, women have a 50% increased risk of chronic obstructive pulmonary disease (COPD) compared with men. The anatomic…”
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3
Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (27-10-2011)“…Patients with COPD have increased peripheral airway resistance. In this study, increased peripheral airway resistance was strongly associated with a reduction…”
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4
Changes in Forced Expiratory Volume in 1 Second over Time in COPD
Published in The New England journal of medicine (29-09-2011)“…In patients with chronic obstructive pulmonary disease (COPD), lung function decreases rapidly. Analysis of data from a large observational study of COPD…”
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5
Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study
Published in The lancet respiratory medicine (01-08-2018)“…The concept that small conducting airways less than 2 mm in diameter become the major site of airflow obstruction in chronic obstructive pulmonary disease…”
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6
Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort
Published in Respiratory medicine (01-09-2013)“…Summary Comorbidities, are common in COPD, have been associated with poor outcomes and are thought to relate to systemic inflammation. To investigate…”
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Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort
Published in The European respiratory journal (01-09-2013)“…The 2011 Global Initiative for Chronic Obstructive Lung Disease (GOLD) classifies patients with chronic obstructive pulmonary disease (COPD) into four groups…”
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Characterisation of COPD heterogeneity in the ECLIPSE cohort
Published in Respiratory research (10-09-2010)“…Chronic obstructive pulmonary disease (COPD) is a complex condition with pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity…”
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Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology
Published in The European respiratory journal (01-02-2018)“…The small conducting airways are the major site of obstruction in chronic obstructive pulmonary disease (COPD). This study examined small airway pathology…”
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10
Small Airway Reduction and Fibrosis Is an Early Pathologic Feature of Idiopathic Pulmonary Fibrosis
Published in American journal of respiratory and critical care medicine (01-11-2021)“…Rationale: To improve disease outcomes in idiopathic pulmonary fibrosis (IPF), it is essential to understand its early pathophysiology so that it can be…”
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11
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes
Published in American journal of respiratory and critical care medicine (01-09-2015)“…Chronic obstructive pulmonary disease (COPD) is defined by the presence of airflow limitation on spirometry, yet subjects with COPD can have marked differences…”
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Pathological Comparisons of Paraseptal and Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-09-2020)“…Rationale: Although centrilobular emphysema (CLE) and paraseptal emphysema (PSE) are commonly identified on multidetector computed tomography (MDCT), little is…”
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Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease
Published in Thorax (01-08-2012)“…Bronchodilator responsiveness is a potential phenotypic characteristic of chronic obstructive pulmonary disease (COPD). We studied whether change in lung…”
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The effect of azithromycin in adults with stable neutrophilic COPD: a double blind randomised, placebo controlled trial
Published in PloS one (22-08-2014)“…Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway disease characterised by neutrophilic airway inflammation or bronchitis. Neutrophilic…”
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COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?
Published in Radiology (01-12-2015)“…To determine the role of imaging measurements of emphysema and airway disease in determining chronic obstructive pulmonary disease (COPD) symptoms and exercise…”
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (24-06-2004)“…Physiological observations indicate that the small airways are the predominant site of airway obstruction in patients with chronic obstructive pulmonary…”
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Quantitative Computed Tomography Measures of Emphysema and Airway Wall Thickness Are Related to Respiratory Symptoms
Published in American journal of respiratory and critical care medicine (15-02-2010)“…There is limited knowledge about the relationship between respiratory symptoms and quantitative high-resolution computed tomography measures of emphysema and…”
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Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study
Published in PloS one (18-11-2016)“…Thoracic computed tomography (CT) scans are widely performed in clinical practice, often leading to detection of airway or parenchymal abnormalities in…”
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Pulmonary ventilation visualized using hyperpolarized helium-3 and xenon-129 magnetic resonance imaging: differences in COPD and relationship to emphysema
Published in Journal of applied physiology (1985) (15-03-2013)“…In subjects with chronic obstructive pulmonary disease (COPD), hyperpolarized xenon-129 ((129)Xe) magnetic resonance imaging (MRI) reveals significantly…”
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20
Loci Identified by Genome-wide Association Studies Influence Different Disease-related Phenotypes in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-12-2010)“…Genome-wide association studies have shown significant associations between variants near hedgehog interacting protein HHIP, FAM13A, and cholinergic nicotinic…”
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