Search Results - "Cox Powell, Pamela"
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Reduced Left Atrial Emptying Fraction and Chymase Activation in Pathophysiology of Primary Mitral Regurgitation
Published in JACC. Basic to translational science (01-02-2020)“…[Display omitted] •Extensive LA fibrosis is related to an increase in LA size and decrease in total LA EF. This supports the contention that the LA is not…”
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Disruption of desmin-mitochondrial architecture in patients with regurgitant mitral valves and preserved ventricular function
Published in The Journal of thoracic and cardiovascular surgery (01-10-2016)“…Abstract Objective Recent studies have demonstrated improved outcomes in patients receiving early surgery for degenerative mitral regurgitation (MR) rather…”
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Mitochondrial haplotype modulates genome expression and mitochondrial structure/function in cardiomyocytes following volume overload
Published in American journal of physiology. Heart and circulatory physiology (01-04-2023)“…Mitochondrial DNA (mtDNA) haplotype regulates mitochondrial structure/function and reactive oxygen species in aortocaval fistula (ACF) in mice. Here, we…”
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Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation
Published in JACC. Basic to translational science (01-10-2022)“…Interstitial collagen loss and cardiomyocyte ultrastructural damage accounts for left ventricular (LV) sphericity and decrease in LV twist and circumferential…”
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