Search Results - "Cox, Susan F"

Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials by Rewell, Sarah S J, Churilov, Leonid, Sidon, T Kate, Aleksoska, Elena, Cox, Susan F, Macleod, Malcolm R, Howells, David W

“…Key disparities between the timing and methods of assessment in animal stroke studies and clinical trial may be part of the reason for the failure to translate…”
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Inducing stroke in aged, hypertensive, diabetic rats by Rewell, Sarah SJ, Fernandez, John A, Cox, Susan F, Spratt, Neil J, Hogan, Lisa, Aleksoska, Elena, van Raay, Leena, Liberatore, Gabriel T, Batchelor, Peter E, Howells, David W

“…Animal models of ischemic stroke often neglect comorbidities common in patients. This study shows the feasibility of inducing stroke by 2 h of thread occlusion…”
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Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing by O'Collins, Victoria E, Macleod, Malcolm R, Cox, Susan F, Van Raay, Leena, Aleksoska, Elena, Donnan, Geoffrey A, Howells, David W

“…There is some evidence that in animal models of acute ischaemic stroke, combinations of neuroprotective agents might be more efficacious than the same agents…”
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Hypothermia revisited: Impact of ischaemic duration and between experiment variability by Rewell, Sarah SJ, Jeffreys, Amy L, Sastra, Steven A, Cox, Susan F, Fernandez, John A, Aleksoska, Elena, van der Worp, H Bart, Churilov, Leonid, Macleod, Malcolm R, Howells, David W

“…To assess the true effect of novel therapies for ischaemic stroke, a positive control that can validate the experimental model and design is vital. Hypothermia…”
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Early Decompression following Cervical Spinal Cord Injury: Examining the Process of Care from Accident Scene to Surgery by Battistuzzo, Camila R, Armstrong, Alex, Clark, Jillian, Worley, Laura, Sharwood, Lisa, Lin, Peny, Rooke, Gareth, Skeers, Peta, Nolan, Sherilyn, Geraghty, Timothy, Nunn, Andrew, Brown, Doug J, Hill, Steven, Alexander, Janette, Millard, Melinda, Cox, Susan F, Rao, Sudhakar, Watts, Ann, Goods, Louise, Allison, Garry T, Agostinello, Jacqui, Cameron, Peter A, Mosley, Ian, Liew, Susan M, Geddes, Tom, Middleton, James, Buchanan, John, Rosenfeld, Jeffrey V, Bernard, Stephen, Atresh, Sridhar, Patel, Alpesh, Schouten, Rowan, Freeman, Brian J C, Dunlop, Sarah A, Batchelor, Peter E

“…Early decompression may improve neurological outcome after spinal cord injury (SCI), but is often difficult to achieve because of logistical issues. The aims…”
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Hypothermia prior to decompression: buying time for treatment of acute spinal cord injury by Batchelor, Peter E, Kerr, Nicole F, Gatt, Amy M, Aleksoska, Elena, Cox, Susan F, Ghasem-Zadeh, Ali, Wills, Taryn E, Howells, David W

“…Human spinal cord injury (SCI) is usually accompanied by persistent cord compression. Experimental data demonstrate that compression of the traumatized cord…”
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Intracanal pressure in compressive spinal cord injury: reduction with hypothermia by Batchelor, Peter E, Kerr, Nicole F, Gatt, Amy M, Cox, Susan F, Ghasem-Zadeh, Ali, Wills, Taryn E, Sidon, Tara K, Howells, David W

“…Most cases of human spinal cord injury (SCI) are accompanied by continuing cord compression. Experimentally, compression results in rapid neurological decline…”
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The Benefit of Hypothermia in Experimental Ischemic Stroke is Not Affected by Pethidine by Sena, Emily S., Jeffreys, Amy L., Cox, Susan F., Sastra, Stephen A., Churilov, Leonid, Rewell, Sarah, Batchelor, Peter E., van der Worp, H. Bart, Macleod, Malcolm R., Howells, David W.

“…Background Hypothermia is a promising experimental treatment for acute ischemic stroke. Human trials are still at an early stage, with the focus now on using…”
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An improved technique for silicone-coating the suture used in rat MCA occlusion increases stroke induction rate, reduces mortality, and is effective across a wide weight and age range by Spratt, Neil J, Fernandez, John A C, Chen, Michelle, Rewell, Sarah S J, Cox, Susan F, van Raay, Leena, Hogan, Lisa, Howells, David W

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