Search Results - "Cox, Russell"

Curiouser and curiouser: progress in understanding the programming of iterative highly-reducing polyketide synthases by Cox, Russell J

“…Covering: 1996-2022Investigations over the last 2 decades have begun to reveal how fungal iterative highly-reducing polyketide synthases are programmed. Both…”
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Oxidative rearrangements during fungal biosynthesis by Cox, Russell

“…Oxidative rearrangements are key reactions during the biosyntheses of many secondary metabolites in fungi. This review highlights the most important examples…”
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The molecular steps of citrinin biosynthesis in fungi by He, Yi, Cox, Russell J

“…The individual steps of citrinin biosynthesis in M7 were determined by a combination of targeted gene knockout and heterologous gene expression in . The…”
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Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets by Cox, Russell J

“…Fungi produce a wide variety of biologically active compounds. Among these, the polyketides form a large and structurally diverse group. These compounds are…”
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Reductive Release from a Hybrid PKS‐NRPS during the Biosynthesis of Pyrichalasin H by Heinemann, Henrike, Zhang, Haili, Cox, Russell J.

“…Three central steps during the biosynthesis of cytochalasan precursors, including reductive release, Knoevenagel cyclisation and Diels Alder cyclisation are…”
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Introducing co-review to RSC Advances by Fisher, Laura, Cox, Russell J, Faulds, Karen

“…now offers the option of co-review for our reviewers. Editors-in-Chief Russell J. Cox and Karen Faulds, and Executive Editor Laura Fisher, offer more detail on…”
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Investigation of chain-length selection by the tenellin iterative highly-reducing polyketide synthase by Schmidt, Katharina, Cox, Russell J

“…The programming of widely distributed iterative fungal hr-PKS is mysterious, yet it is central for generating polyketide natural product diversity by…”
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Synthetic Biology Driven Biosynthesis of Unnatural Tropolone Sesquiterpenoids by Schotte, Carsten, Li, Lei, Wibberg, Daniel, Kalinowski, Jörn, Cox, Russell J.

“…Tropolone sesquiterpenoids (TS) are an intriguing family of biologically active fungal meroterpenoids that arise through a unique intermolecular hetero…”
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Diels–Alder Reactions During the Biosynthesis of Sorbicillinoids by Kahlert, Lukas, Bassiony, Eman F., Cox, Russell J., Skellam, Elizabeth J.

“…The sorbicillinoids are a class of biologically active and structurally diverse fungal polyketides arising from sorbicillin. Through co‐expression of sorA,…”
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Three previously unrecognised classes of biosynthetic enzymes revealed during the production of xenovulene A by Schor, Raissa, Schotte, Carsten, Wibberg, Daniel, Kalinowski, Jörn, Cox, Russell J.

“…Xenovulene A is a complex fungal meroterpenoid, produced by the organism hitherto known as Acremonium strictum IMI 501407, for which limited biosynthetic…”
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Introducing transparent peer review to RSC Advances by Fisher, Laura, Cox, Russell J, Faulds, Karen

“…is introducing the option of transparent peer review for authors. Editors-in-Chief Russell J. Cox and Karen Faulds, and Executive Editor Laura C. Fisher offer…”
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Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi by Chen, Wanping, Chen, Runfa, Liu, Qingpei, He, Yi, He, Kun, Ding, Xiaoli, Kang, Lijing, Guo, Xiaoxiao, Xie, Nana, Zhou, Youxiang, Lu, Yuanyuan, Cox, Russell J, Molnár, István, Li, Mu, Shao, Yanchun, Chen, Fusheng

“…azaphilone pigments (MonAzPs) are very widely used as food colorants, but their biosynthetic pathway has remained poorly characterized for more than half a…”
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Targeted Gene Inactivations Expose Silent Cytochalasans in Magnaporthe grisea NI980 by Wang, Chongqing, Hantke, Verena, Cox, Russell J, Skellam, Elizabeth

“…The biosynthetic gene cluster encoding the phytotoxin pyrichalasin H 5 was discovered in Magnaporthe grisea NI980, and the late-stage biosynthetic pathway of 5…”
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Engineered and total biosynthesis of fungal specialized metabolites by Cox, Russell J.

“…Filamentous fungi produce a very wide range of complex and often bioactive metabolites, demonstrating their inherent ability as hosts of complex biosynthetic…”
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Introduction to engineering the biosynthesis of fungal natural products by Cox, Russell J, Gulder, Tobias A M

“…Filamentous fungi are highly diverse eukaryotes that inhabit all known ecosystems on earth. Estimates suggest that more than 2 × 10 species are likely to…”
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Understanding and Engineering the Stereoselectivity of Humulene Synthase by Schotte, Carsten, Lukat, Peer, Deuschmann, Adrian, Blankenfeldt, Wulf, Cox, Russell J.

“…The non‐canonical terpene cyclase AsR6 is responsible for the formation of 2E,6E,9E‐humulene during the biosynthesis of the tropolone sesquiterpenoid (TS)…”
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Evidence for enzyme catalysed intramolecular [4+2] Diels-Alder cyclization during the biosynthesis of pyrichalasin H by Hantke, Verena, Skellam, Elizabeth J, Cox, Russell J

“…Cytochalasans are highly complex fungal metabolites which exhibit diverse biological activities. Little is known of the chemical steps involved in the…”
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The same but different: multiple functions of the fungal flavin dependent monooxygenase SorD from Penicillium chrysogenum by Kahlert, Lukas, Cox, Russell J, Skellam, Elizabeth

“…Sorbicillinoids are a large family of fungal secondary metabolites with a diverse range of structures and numerous bioactivites, some of which have…”
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The sporothriolides. A new biosynthetic family of fungal secondary metabolites by Tian, Dong-Song, Kuhnert, Eric, Ouazzani, Jamal, Wibberg, Daniel, Kalinowski, Jörn, Cox, Russell J

“…The biosynthetic gene cluster of the antifungal metabolite sporothriolide 1 was identified from three producing ascomycetes: Hypomontagnella monticulosa MUCL…”
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Recent advances in reconstructing microbial secondary metabolites biosynthesis in Aspergillus spp by He, Yi, Wang, Bin, Chen, Wanping, Cox, Russell J., He, Jingren, Chen, Fusheng

“…High throughput genome sequencing has revealed a multitude of potential secondary metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction…”
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