Search Results - "Cox, Nathan J."

Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia by Cooper, Matthew J, Cox, Nathan J, Zimmerman, Eric I, Dewar, Brian J, Duncan, James S, Whittle, Martin C, Nguyen, Thien A, Jones, Lauren S, Ghose Roy, Sreerupa, Smalley, David M, Kuan, Pei Fen, Richards, Kristy L, Christopherson, Richard I, Jin, Jian, Frye, Stephen V, Johnson, Gary L, Baldwin, Albert S, Graves, Lee M

“…Protein kinases play key roles in oncogenic signaling and are a major focus in the development of targeted cancer therapies. Imatinib, a BCR-Abl tyrosine…”
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A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking by Cox, Nathan J, Luo, Peter M, Smith, Timothy J, Bisnett, Brittany J, Soderblom, Erik J, Boyce, Michael

“…O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans,…”
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Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins by Toleman, Clifford A., Schumacher, Maria A., Yu, Seok-Ho, Zeng, Wenjie, Cox, Nathan J., Smith, Timothy J., Soderblom, Erik J., Wands, Amberlyn M., Kohler, Jennifer J., Boyce, Michael

“…O-GlcNAc is an intracellular posttranslational modification that governs myriad cell biological processes and is dysregulated in human diseases. Despite this…”
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Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway by Cox, Nathan J, Unlu, Gokhan, Bisnett, Brittany J, Meister, Thomas R, Condon, Brett M, Luo, Peter M, Smith, Timothy J, Hanna, Michael, Chhetri, Abhishek, Soderblom, Erik J, Audhya, Anjon, Knapik, Ela W, Boyce, Michael

“…The COPII coat complex, which mediates secretory cargo trafficking from the endoplasmic reticulum, is a key control point for subcellular protein targeting…”
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Lyn regulates creatine uptake in an imatinib-resistant CML cell line by Okumu, Denis O., Aponte-Collazo, Lucas J., Dewar, Brian J., Cox, Nathan J., East, Michael P., Tech, Katherine, McDonald, Ian M., Tikunov, Andrey P., Holmuhamedov, Ekhson, Macdonald, Jeffrey M., Graves, Lee M.

“…Imatinib mesylate (imatinib) is the first-line treatment for newly diagnosed chronic myeloid leukemia (CML) due to its remarkable hematologic and cytogenetic…”
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Role of O‐GlcNAcylation in SEC24C function by Lamb, Caitlin, Bisnett, Brittany, Cox, Nathan J., Smith, Tim, Boyce, Michael

“…Abstract only…”
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Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia. e66755 by Cooper, Matthew J, Cox, Nathan J, Zimmerman, Eric I, Dewar, Brian J, Duncan, James S, Whittle, Martin C, Nguyen, Thien A, Jones, Lauren S, Roy, Sreerupa Ghose, Smalley, David M

“…Protein kinases play key roles in oncogenic signaling and are a major focus in the development of targeted cancer therapies. Imatinib, a BCR-Abl tyrosine…”
Get full text