Search Results - "Cox, N.J."

A Coding Polymorphism in PFAS (The Gene Encoding Phosphoribosylformylglycinamidine Synthase) Is a Determinant of Prostacyclin Dose by Thomeas, V, Maitland, M.L, Benza, R.L, Tamari, M, Gamazon, E.R, Konkashbaev, A, Wheeler, H, Hirota, T, Kubo, M, Cox, N.J, Gomberg-Maitland, M

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Guidelines for investigating causality of sequence variants in human disease by MacArthur, D. G., Manolio, T. A., Dimmock, D. P., Rehm, H. L., Shendure, J., Abecasis, G. R., Adams, D. R., Altman, R. B., Antonarakis, S. E., Ashley, E. A., Barrett, J. C., Biesecker, L. G., Conrad, D. F., Cooper, G. M., Cox, N. J., Daly, M. J., Gerstein, M. B., Goldstein, D. B., Hirschhorn, J. N., Leal, S. M., Pennacchio, L. A., Stamatoyannopoulos, J. A., Sunyaev, S. R., Valle, D., Voight, B. F., Winckler, W., Gunter, C.

“…Acceleration in discovery of rare genetic variants possibly linked with disease may mean an increased risk of false-positive reports of causality; this…”
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A climatic index for soil erosion potential (CSEP) including seasonal and vegetation factors by Kirkby, M.J., Cox, N.J.

“…The concept of Cumulative Erosion Potential (CEP) proposed by De Ploey, Kirkby and Ahnert in 1991 ( Earth Surf. Process. Landforms, 16: 399–409) provides a…”
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Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits by Maranville, J C, Cox, N J

“…It has been suggested that pharmacogenomic phenotypes are influenced by genetic variants with larger effect sizes than other phenotypes, such as complex…”
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Rapid, climate-driven changes in outlet glaciers on the Pacific coast of East Antarctica by Miles, B. W. J., Stokes, C. R., Vieli, A., Cox, N. J.

“…Multidecadal trends in the terminus position of outlet glaciers along the margin of the East Antarctic ice sheet reveal three epochal patterns of glacier…”
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Poor Appetite Is Associated with Six Month Mortality in Hospitalised Older Men and Women by Cox, N. J., Lim, S. ER, Howson, F., Moyses, H., Ibrahim, K., Sayer, A. A., Roberts, H. C., Robinson, S. M.

“…Objectives Appetite loss is common in hospitalised older individuals but not routinely assessed. Poor appetite in hospital has previously been identified as…”
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Two Polymorphic Gene Loci Associated with Treprostinil Dose in Pulmonary Arterial Hypertension by Psotka, M.A., Thomeas-McEwing, V., Gamazon, E.R., Hirota, T., Friedman, P.N., Konkashbaev, A., Kubo, M., Nakamura, Y., Ratain, M.J., Benza, R.L., Cox, N.J., Gomberg-Maitland, M.I., Maitland, M.L.

“…Prostacyclin infusion is an effective therapy for pulmonary arterial hypertension (PAH) but has variable clinical response and dosing requirements. We…”
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Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior by Wakschlag, L S, Kistner, E O, Pine, D S, Biesecker, G, Pickett, K E, Skol, A D, Dukic, V, Blair, R J R, Leventhal, B L, Cox, N J, Burns, J L, Kasza, K E, Wright, R J, Cook, E H

“…Genetic susceptibility to antisocial behavior may increase fetal sensitivity to prenatal exposure to cigarette smoke. Testing putative gene × exposure…”
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Estimates of Deaths Associated with Seasonal Influenza — United States, 1976–2007 by Thompson, M.G, Shay, D.K, Zhou, H, Bridges, C.B, Cheng, P.Y, Burns, E, Bresee, J.S, Cox, N.J

“…Influenza infections are associated with thousands of deaths every year in the United States, with the majority of deaths from seasonal influenza occurring…”
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Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism by Delahanty, R J, Kang, J Q, Brune, C W, Kistner, E O, Courchesne, E, Cox, N J, Cook, E H, Macdonald, R L, Sutcliffe, J S

“…Maternal 15q11-q13 duplication is the most common copy number variant in autism, accounting for ∼1–3% of cases. The 15q11-q13 region is subject to epigenetic…”
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relationship between rainfall inputs and flood generation in south-east Spain by Bracken ' née Bull ', L.J, Cox, N.J, Shannon, J

“…Rainfall and flood data are relatively sparse in semi-arid areas; hence there have been relatively few investigations into the relationships between rainfall…”
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Assessing agreement of measurements and predictions in geomorphology by Cox, Nicholas J.

“…Commonly in geomorphology measurements by different methods are compared to see how far they agree (i.e. are equal), as are predictions from models and…”
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Ethnic variation of TET2 SNP rs2454206 and association with clinical outcome in childhood AML: a report from the Children’s Oncology Group by Kutny, M A, Alonzo, T A, Gamazon, E R, Gerbing, R B, Geraghty, D, Lange, B, Heerema, N A, Sung, L, Aplenc, R, Franklin, J, Raimondi, S C, Hirsch, B A, Konkashbaev, A, Cox, N J, Onel, K, Gamis, A S, Meshinchi, S

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Establishment of CYP2D6 reference samples by multiple validated genotyping platforms by Fang, H, Liu, X, Ramírez, J, Choudhury, N, Kubo, M, Im, H K, Konkashbaev, A, Cox, N J, Ratain, M J, Nakamura, Y, O'Donnell, P H

“…Cytochrome P450 2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6)), a highly polymorphic drug-metabolizing enzyme, is involved in the…”
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Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations by Wheeler, H E, Gamazon, E R, Stark, A L, O'Donnell, P H, Gorsic, L K, Huang, R S, Cox, N J, Dolan, M E

“…Platinating agents are used in the treatment of many cancers, yet they can induce toxicities and resistance that limit their utility. Using previously…”
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The antigenicity and evolution of influenza H1 haemagglutinin, from 1950-1957 and 1977-1983: two pathways from one gene by Raymond, F L, Caton, A J, Cox, N J, Kendal, A P, Brownlee, G G

“…Nucleotide sequence analysis of the region of the haemagglutinin gene coding for the HA1 domain of the protein was performed on 19 human influenza A strains of…”
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Kernel estimation as a basic tool for geomorphological data analysis by Cox, Nicholas J.

“…Kernel estimation, based on the convolution of a probability density function with a set of magnitudes or event dates, provides tuneable smooth pictures of…”
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Fitting concentration and load rating curves with generalized linear models by Cox, Nicholas J., Warburton, Jeff, Armstrong, Alona, Holliday, Victoria J.

“…Generalized linear models may be used as a systematic and flexible alternative to existing practices in fitting sediment or solute concentration and load…”
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Relative sea level curves for the South Shetland Islands and Marguerite Bay, Antarctic Peninsula by Bentley, M.J., Hodgson, D.A., Smith, J.A., Cox, N.J.

“…This paper presents preliminary relative sea level curves for the Marguerite Bay region and for the South Shetland Islands. The Marguerite Bay curve is…”
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Characterization of an influenza A H5N2 reassortant as a candidate for live-attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential by Desheva, J.A., Lu, X.H., Rekstin, A.R., Rudenko, L.G., Swayne, D.E., Cox, N.J., Katz, J.M., Klimov, A.I.

“…We generated a high-growth 7:1 reassortant (Len17/H5) that contained the hemagglutinin (HA) gene from non-pathogenic A/Duck/Potsdam/1402-6/86 (H5N2) virus and…”
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