Search Results - "Cox, M.J."

Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older by Dunkle, Lisa M, Izikson, Ruvim, Patriarca, Peter, Goldenthal, Karen L, Muse, Derek, Callahan, Janice, Cox, Manon M.J

“…Influenza epidemics cause substantial morbidity. The seasonal vaccine, an important control measure, is not completely efficacious. This trial assessed the…”
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Recombinant protein vaccines produced in insect cells by Cox, Manon M.J

“…Highlights ► BEVS has matured into a commercial manufacturing technology. ► A broad range of vaccines can be produced in a universal “plug and play” process. ►…”
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Formal to informal learning with IT: research challenges and issues for e-learning by Cox, M.J.

“…For the purpose of clarity and consistency, the term e‐learning is used throughout the paper to refer to technology‐enhanced learning and information…”
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Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax™ polysaccharide adjuvant by Gordon, David L, Sajkov, Dimitar, Woodman, Richard J, Honda-Okubo, Yoshikazu, Cox, Manon M.J, Heinzel, Susanne, Petrovsky, Nikolai

“…Highlights ► Randomized clinical trial of a novel adjuvanted H1N1/2009 pandemic influenza vaccine. ► Reports first pandemic use of a vaccine based on…”
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Technology transfer and scale-up of the Flublok® recombinant hemagglutinin (HA) influenza vaccine manufacturing process by Buckland, Barry, Boulanger, Robert, Fino, Mireli, Srivastava, Indresh, Holtz, Kathy, Khramtsov, Nikolai, McPherson, Clifton, Meghrous, Jamal, Kubera, Paul, Cox, Manon M.J

“…Highlights • Successful fivefold scale-up to 2500 L scale of first FDA licensed recombinant influenza vaccine. • FDA licensed process is reproducible for a…”
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Development and Validation of a Hopkinson Bar for Hazardous Materials by Quinn, R.M., Zhang, L.H., Cox, M.J., Townsend, D., Cartwright, T., Aldrich-Smith, G., Hooper, P.A., Dear, J.P.

“…Background There are a variety of approaches that can be employed for Hopkinson bar compression testing and there is no standard procedure. Objectives A…”
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FluBlok, a next generation influenza vaccine manufactured in insect cells by Cox, Manon M.J., Hollister, Jason R.

“…FluBlok, a recombinant trivalent hemagglutinin (rHA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive…”
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The effect of impurity inclusions on the pitting corrosion behaviour of beryllium by Punni, J.S., Cox, M.J.

“…An electrochemical polarisation study has been conducted to determine the effect of impurity inclusions on the pitting corrosion behaviour of beryllium. Three…”
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Expression and purification of an influenza hemagglutinin—one step closer to a recombinant protein-based influenza vaccine by Wang, Keyang, Holtz, Kathleen M., Anderson, Karl, Chubet, Richard, Mahmoud, Wafaa, Cox, Manon M.J.

“…Numerous human infections with avian influenza viruses in Asia in recent years have raised the concern that the next influenza pandemic is imminent. The most…”
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FluBlok, a recombinant hemagglutinin influenza vaccine by Cox, Manon M.J., Patriarca, Peter A., Treanor, John

“…FluBlok, a recombinant trivalent hemagglutinin (HA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive…”
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A fast track influenza virus vaccine produced in insect cells by Cox, Manon M.J., Hashimoto, Yoshifumi

“…[Display omitted] ► A recombinant hemagglutinin vaccine (FluBlok) is produced in insect cells. ► Characterization of cell substrate revealed no evidence of…”
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Plant species responses along a grazing disturbance gradient in Australian grassland by Fensham, R.J, Holman, J.E, Cox, M.J

“…Floristic data from paired roadside-paddock analyses from grassland in central Queensland, Australia, were ordinated. The mean direction of the vectors between…”
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Randomized comparison of the safety of Flublok® versus licensed inactivated influenza vaccine in healthy, medically stable adults ≥50 years of age by Izikson, Ruvim, Leffell, David J, Bock, S. Allan, Patriarca, Peter A, Post, Penny, Dunkle, Lisa M, Cox, Manon M.J

“…Abstract Background The safety and tolerability of Flublok® , a purified recombinant hemagglutinin seasonal influenza vaccine, was compared to AFLURIA® in a…”
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Dissolved carbon dioxide determines the productivity of a recombinant hemagglutinin component of an influenza vaccine produced by insect cells by Meghrous, Jamal, Khramtsov, Nikolai, Buckland, Barry C., Cox, Manon M.J., Palomares, Laura A., Srivastava, Indresh K.

“…ABSTRACT Dissolved carbon dioxide (dCO2) accumulation during cell culture has been recognized as an important parameter that needs to be controlled for…”
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Improved stability of recombinant hemagglutinin using a formulation containing sodium thioglycolate by Rhodes, David G, Holtz, Kathy, Robinson, Pam, Wang, Keyang, McPherson, Clifton E, Cox, Manon M.J, Srivastava, Indresh K

“…Abstract This study was designed to improve the stability of liquid formulations of recombinant influenza hemagglutinin (rHA) and to understand the mechanism…”
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Vaccine Technology V: The art of taking vaccines to disease prevention by Palomares, Laura A, Buckland, Barry C, Genzel, Yvonne, Cox, Manon M.J

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An experimental methodology to characterise post-necking behaviour and quantify ductile damage accumulation in isotropic materials by Sancho, A., Cox, M.J., Cartwright, T., Davies, C.M., Hooper, P.A., Dear, J.P.

“…The development of ductile damage, that occurs beyond the point of necking in a tensile test, can be difficult to quantify. An experimental methodology has…”
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Innovations in vaccine development: can regulatory authorities keep up? by Cox, Manon M J, Onraedt, Annelies

“…Vaccine Production Summit San Francisco, CA, USA, 4-6 June 2012 IBC's 3rd Vaccine Production Summit featured 28 presentations discussing regulatory challenges…”
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Uniaxial compression of single crystal and polycrystalline tantalum by Whiteman, G., Case, S., Millett, J.C.F., Cox, M.J., Avraam, P., Dear, J.P., Sancho, A., Hooper, P.A.

“…A series of compression experiments characterising the elastic-plastic response of single crystal and polycrystalline tantalum from quasi-static to…”
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Evaluation of the Virus Counter ® for rapid baculovirus quantitation by Ferris, Matthew M., Stepp, Patricia C., Ranno, Kirk A., Mahmoud, Wafaa, Ibbitson, Elizabeth, Jarvis, James, Cox, Manon M.J., Christensen, Kurt, Votaw, Heather, Edwards, Dean P., Rowlen, Kathy L.

“…The utility of a new instrument for rapid virus quantitation, the Virus Counter, was evaluated in a blind study conducted at three sites. This instrument is a…”
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