Search Results - "Cox, Laura"
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Antibiotics in early life and obesity
Published in Nature reviews. Endocrinology (01-03-2015)“…Colonization of an infant with their microbiota in early life is important for normal development of host metabolism. In this Perspectives article, Cox and…”
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The Need for Multi-Omics Biomarker Signatures in Precision Medicine
Published in International journal of molecular sciences (26-09-2019)“…Recent advances in omics technologies have led to unprecedented efforts characterizing the molecular changes that underlie the development and progression of a…”
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Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences
Published in Cell (14-08-2014)“…Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the…”
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Pathways in Microbe-Induced Obesity
Published in Cell metabolism (04-06-2013)“…Diet, host gene composition, and alterations in the intestinal microbiota can contribute to obesity. In microbe-induced obesity, metabolic changes stem from…”
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Integrated omics: tools, advances and future approaches
Published in Journal of molecular endocrinology (01-01-2019)“…With the rapid adoption of high-throughput omic approaches to analyze biological samples such as genomics, transcriptomics, proteomics and metabolomics, each…”
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Microbiota Signaling Pathways that Influence Neurologic Disease
Published in Neurotherapeutics (2018)“…Though seemingly distinct and autonomous, emerging evidence suggests there is a bidirectional interaction between the intestinal microbiota and the brain. This…”
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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions
Published in PLoS biology (17-08-2020)“…In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue…”
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Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
Published in Nature medicine (01-03-2016)“…The microbiota of cesarean-born infants can be partially restored to that of vaginally born infants immediately after birth. Exposure of newborns to the…”
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DDR1 Deficiency in Mice: A Spontaneous Model of Bronchopulmonary Dysplasia-associated Pulmonary Hypertension?
Published in American journal of respiratory cell and molecular biology (01-11-2022)“…Cataltepe and Cox discuss the study by Q. A. Bonafiglia and colleagues on cardiovascular and pulmonary effects of DDR1 (discoidin domain receptor 1) deficiency…”
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Alterations of the human gut microbiome in multiple sclerosis
Published in Nature communications (28-06-2016)“…The gut microbiome plays an important role in immune function and has been implicated in several autoimmune disorders. Here we use 16S rRNA sequencing to…”
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The gut microbiota influences skeletal muscle mass and function in mice
Published in Science translational medicine (24-07-2019)“…The functional interactions between the gut microbiota and the host are important for host physiology, homeostasis, and sustained health. We compared the…”
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Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila
Published in Cell host & microbe (11-12-2019)“…Fecal transfer from healthy donors is being explored as a microbiome modality. MicroRNAs (miRNAs) have been found to affect the microbiome. Multiple sclerosis…”
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Helminth colonization is associated with increased diversity of the gut microbiota
Published in PLoS neglected tropical diseases (01-05-2014)“…Soil-transmitted helminths colonize more than 1.5 billion people worldwide, yet little is known about how they interact with bacterial communities in the gut…”
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A probiotic modulates the microbiome and immunity in multiple sclerosis
Published in Annals of neurology (01-06-2018)“…Objective Effect of a probiotic on the gut microbiome and peripheral immune function in healthy controls and relapsing‐remitting multiple sclerosis (MS)…”
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Autoimmunity and the microbiome
Published in Immunological reviews (01-08-2024)Get full text
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Gut Microbiome in Progressive Multiple Sclerosis
Published in Annals of neurology (01-06-2021)“…Objective This study was undertaken to investigate the gut microbiome in progressive multiple sclerosis (MS) and how it relates to clinical disease. Methods We…”
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Distinct Polysaccharide Utilization Profiles of Human Intestinal Prevotella copri Isolates
Published in Cell host & microbe (13-11-2019)“…Gut-dwelling Prevotella copri (P. copri), the most prevalent Prevotella species in the human gut, have been associated with diet and disease. However, our…”
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Gastric Helicobacter pylori Infection Affects Local and Distant Microbial Populations and Host Responses
Published in Cell reports (Cambridge) (16-02-2016)“…Helicobacter pylori is a late-in-life human pathogen with potential early-life benefits. Although H. pylori is disappearing from the human population, little…”
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Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice
Published in Scientific reports (29-11-2019)“…Alzheimer’s disease (AD) affects an estimated 5.8 million Americans, and advanced age is the greatest risk factor. AD patients have altered intestinal…”
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Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment
Published in Nature communications (30-06-2015)“…Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic…”
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