Search Results - "Cox, D A"

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling by Hanker, A B, Mitin, N, Wilder, R S, Henske, E P, Tamanoi, F, Cox, A D, Der, C J

“…The Rheb1 and Rheb2 small GTPases and their effector mTOR are aberrantly activated in human cancer and are attractive targets for anti-cancer drug discovery…”
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INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer by Zhang, S, Zhou, B, Wang, L, Li, P, Bennett, B D, Snyder, R, Garantziotis, S, Fargo, D C, Cox, A D, Chen, L, Hu, G

“…Epigenetic regulators are attractive targets for the development of new cancer therapies. Among them, the ATP-dependent chromatin remodeling complexes control…”
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Proceedings of a workshop to discuss the epidemiology of invasive Haemophilus influenzae disease with emphasis on serotype a and b in the Americas, 2019 by Cox, A.D., Kuo Lee, R., Ulanova, M., Bruce, M.G., Tsang, R.S.W.

“…On March 9, 2019, a one-day workshop titled “The current epidemiology of invasive Haemophilus influenzae disease in the Americas”, jointly organized by the…”
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Comparison of polysaccharide glycoconjugates as candidate vaccines to combat Clostridiodes (Clostridium) difficile by Cox, A.D., St. Michael, F., Aubry, A., Strong, P.C.R., Hayes, A.C., Logan, S.M.

“…Two known Clostridiodes (Clostridium) difficile surface antigens, a lipoteichoic acid (LTA) and a polysaccharide (PS-II) were isolated and purified in order to…”
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Intergenerational transmission of somatization behaviour: a study of chronic somatizers and their children by Craig, T K J, Cox, A D, Klein, K

“…Exposure to an ill parent in childhood may be a risk factor for adult somatization. This study examines the hypothesis that somatizing adults are more likely…”
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Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass by Downs, R. W. Jr, Moffett, A. M, Ghosh, A, Cox, D. A, Dowsett, S. A, Harper, K

“…Summary In this Phase 2 study of postmenopausal women with low bone, arzoxifene (a selective estrogen receptor modulator (SERM)) significantly reduced bone…”
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The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women : A randomized, controlled trial by WALSH, B. W, PAUL, S, WILD, R. A, DEAN, R. A, TRACY, R. P, COX, D. A, ANDERSON, P. W

“…C-Reactive protein and homocysteine are independent risk factors for the development of cardiovascular disease. This study compared the effects of hormone…”
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Arzoxifene versus raloxifene: effect on bone and safety parameters in postmenopausal women with osteoporosis by Kendler, D. L., Palacios, S., Cox, D. A., Stock, J., Alam, J., Dowsett, S. A., Zanchetta, J.

“…Summary Arzoxifene increased bone mineral density and decreased bone turnover to a significantly greater extent than raloxifene. The hot flush incidence was…”
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Candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: Developmental chemistry and investigation of immunological responses following immunization of mice and rabbits by Cox, A.D., Zou, W., Gidney, M.A.J., Lacelle, S., Plested, J.S., Makepeace, K., Wright, J.C., Coull, P.A., Moxon, E.R., Richards, J.C.

“…Glycoconjugates were prepared by covalently linking the immunogenic protein carrier CRM 197 to O-deacylated lipopolysaccharide (LPS) derived from Neisseria…”
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Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar by Schmid, P, Itin, P, Cherry, G, Bi, C, Cox, DA

“…In the present study we have analyzed and compared, by immunohistochemistry and in situ hybridization, the expression pattern of the R4/ALK5 transforming…”
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Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: conjugates based on core oligosaccharides by St. Michael, F., Cairns, C. M., Filion, A. L., Biolchi, A., Brunelli, B., Giuliani, M., Richards, J. C., Cox, A. D.

“…In this study we have prepared glycoconjugates with core oligosaccharides (OS) from the lipopolysaccharide (LPS) of Neisseria meningitidis , thus avoiding the…”
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Farnesyltransferase inhibitors potential role in the treatment of cancer by COX, Adrienne D

“…New targets for drug discovery have been identified rapidly as a result of the many recent and rapid advances in the understanding of signal transduction…”
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Siderophore Production by Cystic Fibrosis Isolates of Burkholderia cepacia by DARLING, P, CHAN, M, COX, A. D, SOKOL, P. A

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Isoprenoid Addition to Ras Protein is the Critical Modification for its Membrane Association and Transforming Activity by Kato, Kiyoko, Cox, Adrienne D., Hisaka, Mark M., Graham, Suzanne M., Buss, Janice E., Der, Channing J.

“…We have introduced a variety of amino acid substitutions into carboxyl-terminal CA1A2X sequence (C = cysteine; A = aliphatic; X = any amino acid) of the…”
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Intergenerational transmission of somatization behaviour: 2. Observations of joint attention and bids for attention by Craig, T K J, Bialas, I, Hodson, S, Cox, A D

“…Somatoform disorders may have their roots in childhood through processes that involve an enhanced parental focus on health. The aim of this study was to test…”
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Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction by Sorajja, Paul, Gersh, Bernard J., Cox, David A., McLaughlin, Michael G., Zimetbaum, Peter, Costantini, Costantino, Stuckey, Thomas, Tcheng, James E., Mehran, Roxana, Lansky, Alexandra J., Grines, Cindy L., Stone, Gregg W.

“…Aims We sought to investigate the impact of multivessel coronary artery disease (CAD) on reperfusion success and prognosis following primary percutaneous…”
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Effects of oxidized low-density lipoprotein on vascular contraction and relaxation: clinical and pharmacological implications in atherosclerosis by Cox, D A, Cohen, M L

“…Oxidized LDL exerts profound effects on the vasomotor response of isolated blood vessels to various stimuli that closely mimic the vascular dysfunction…”
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L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases by Rhoads, J M, Argenzio, R A, Chen, W, Rippe, R A, Westwick, J K, Cox, A D, Berschneider, H M, Brenner, D A

“…We studied the mechanisms by which L-glutamine (Gln), a major fuel for enterocytes, signals proliferation in intestinal epithelial cell lines. Gln was additive…”
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Angiographic and clinical characteristics associated with increased in-hospital mortality in elderly patients with acute myocardial infarction undergoing percutaneous intervention (a pooled analysis of the primary angioplasty in myocardial infarction trials) by DeGeare, Vincent S, Stone, Gregg W, Grines, Lorelei, Brodie, Bruce R, Cox, David A, Garcia, Eulogio, Wharton, Thomas P, Boura, Judith A, O’Neill, William W, Grines, Cindy L

“…Advanced age is associated with increased mortality in acute myocardial infarction (AMI) but the mechanism remains unclear. We performed a pooled analysis of…”
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Rab1b Regulates Vesicular Transport between the Endoplasmic Reticulum and Successive Golgi Compartments by Plutner, Helen, Cox, Adrienne D., Pind, Steven, Khosravi-Far, Roya, Bourne, Jeffrey R., Schwaninger, Ruth, Der, Channing J., Balch, William E.

“…We report an essential role for the ras-related small GTP-binding protein rab1b in vesicular transport in mammalian cells. mAbs detect rab1b in both the ER and…”
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