Search Results - "Cox, Charlotte"

Investigating CD99 Expression in Leukemia Propagating Cells in Childhood T Cell Acute Lymphoblastic Leukemia by Cox, Charlotte V, Diamanti, Paraskevi, Moppett, John P, Blair, Allison

“…A significant number of children with T-lineage acute lymphoblastic leukemia (T-ALL) fail to respond to therapy and experience early relapse. CD99 has been…”
Get full text

Mothers Do Not Show Increased Offspring Avoidance and Elevated Corticosterone Levels during Weaning Conflict in Rats by Cox, Charlotte, Hager, Reinmar

“…Parent-offspring conflict is predicted to occur because offspring will demand more parental investment than is optimal for the parent, and is said to be…”
Get full text

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia by Diamanti, Paraskevi, Cox, Charlotte V., Moppett, John P., Blair, Allison

“…Approximately 20% of children with acute lymphoblastic leukemia (ALL) relapse because of failure to eradicate the disease. Current drug efficacy studies focus…”
Get full text

Investigating the response of paediatric leukaemia‐propagating cells to BCL‐2 inhibitors by Diamanti, Paraskevi, Ede, Benjamin C., Dace, Phoebe EI, Barendt, William J., Cox, Charlotte V., Hancock, Jeremy P., Moppett, John P., Blair, Allison

“…Summary Relapse of paediatric acute lymphoblastic leukaemia (ALL) may occur due to persistence of resistant cells with leukaemia‐propagating ability (LPC). In…”
Get full text

Dual targeting of Hsp90 in childhood acute lymphoblastic leukaemia by Diamanti, Paraskevi, Cox, Charlotte V., Moppett, John P., Blair, Allison

Get full text

Targeting miR-423-5p Reverses Exercise Training–Induced HCN4 Channel Remodeling and Sinus Bradycardia by D’Souza, Alicia, Pearman, Charles M, Wang, Yanwen, Nakao, Shu, Logantha, Sunil Jit R.J, Cox, Charlotte, Bennett, Hayley, Zhang, Yu, Johnsen, Anne Berit, Linscheid, Nora, Poulsen, Pi Camilla, Elliott, Jonathan, Coulson, Jessica, McPhee, Jamie, Robertson, Abigail, da Costa Martins, Paula A, Kitmitto, Ashraf, Wisløff, Ulrik, Cartwright, Elizabeth J, Monfredi, Oliver, Lundby, Alicia, Dobrzynski, Halina, Oceandy, Delvac, Morris, Gwilym M, Boyett, Mark R

“…RATIONALE:Downregulation of the pacemaking ion channel, HCN4 (hyperpolarization-activated cyclic nucleotide gated channel 4), and the corresponding ionic…”
Get full text

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate by D’Souza, Alicia, Wang, Yanwen, Anderson, Cali, Bucchi, Annalisa, Baruscotti, Mirko, Olieslagers, Servé, Mesirca, Pietro, Johnsen, Anne Berit, Mastitskaya, Svetlana, Ni, Haibo, Zhang, Yu, Black, Nicholas, Cox, Charlotte, Wegner, Sven, Bano-Otalora, Beatriz, Petit, Cheryl, Gill, Eleanor, Logantha, Sunil Jit R.J., Dobrzynski, Halina, Ashton, Nick, Hart, George, Zhang, Rai, Zhang, Henggui, Cartwright, Elizabeth J., Wisloff, Ulrik, Mangoni, Matteo E., da Costa Martins, Paula A., Piggins, Hugh D., DiFrancesco, Dario, Boyett, Mark R.

“…Heart rate follows a diurnal variation, and slow heart rhythms occur primarily at night. The lower heart rate during sleep is assumed to be neural in origin,…”
Get full text

Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes by Mesirca, Pietro, Nakao, Shu, Nissen, Sarah Dalgas, Forte, Gabriella, Anderson, Cali, Trussell, Tariq, Li, Jue, Cox, Charlotte, Zi, Min, Logantha, Sunil, Yaar, Sana, Cartensen, Helena, Bidaud, Isabelle, Stuart, Luke, Soattin, Luca, Morris, Gwilym M., da Costa Martins, Paula A., Cartwright, Elizabeth J., Oceandy, Delvac, Mangoni, Matteo E., Jespersen, Thomas, Buhl, Rikke, Dobrzynski, Halina, Boyett, Mark R., D’Souza, Alicia

“…[Figure: see text]…”
Get full text

Expression of CD133 on leukemia-initiating cells in childhood ALL by Cox, Charlotte V., Diamanti, Paraskevi, Evely, Roger S., Kearns, Pamela R., Blair, Allison

“…Optimization of therapy for childhood acute lymphoblastic leukemia (ALL) requires a greater understanding of the cells that proliferate to maintain this…”
Get full text

Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia by Williams, Mark T.S., Yousafzai, Yasar, Cox, Charlotte, Blair, Allison, Carmody, Ruaidhrí, Sai, Shuji, Chapman, Karen E., McAndrew, Rachel, Thomas, Angela, Spence, Alison, Gibson, Brenda, Graham, Gerard J., Halsey, Christina

“…Genome-wide association studies have consistently implicated the interleukin-15 (IL-15) gene in acute lymphoblastic leukemia (ALL) biology, including…”
Get full text

Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy by Diamanti, Paraskevi, Cox, Charlotte V., Ede, Benjamin C., Uger, Robert A., Moppett, John P., Blair, Allison

“…Treating refractory pediatric acute lymphoblastic leukemia (ALL) remains a challenge despite impressive remission rates (>90%) achieved in the last decade. The…”
Get full text

Characterization of acute lymphoblastic leukemia progenitor cells by Cox, Charlotte V., Evely, Roger S., Oakhill, Anthony, Pamphilon, Derwood H., Goulden, Nicholas J., Blair, Allison

“…Only some acute lymphoblastic leukemia (ALL) cells are thought to be capable of proliferating to maintain the leukemic clone, and these cells may be the most…”
Get full text

Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia by Cox, Charlotte V., Martin, Hannah M., Kearns, Pamela R., Virgo, Paul, Evely, Roger S., Blair, Allison

“…A significant proportion of children with T-cell acute lymphoblastic leukemia (T-ALL) continue to fail therapy. Consequently, characterization of the cells…”
Get full text

Key features of the environment promoting liver cancer in the absence of cirrhosis by Zaki, Marco Youssef William, Mahdi, Ahmed Khairallah, Patman, Gillian Lucinda, Whitehead, Anna, Maurício, João Pais, McCain, Misti Vanette, Televantou, Despina, Abou-Beih, Sameh, Ramon-Gil, Erik, Watson, Robyn, Cox, Charlotte, Leslie, Jack, Wilson, Caroline, Govaere, Olivier, Lunec, John, Mann, Derek Austin, Nakjang, Sirintra, Oakley, Fiona, Shukla, Ruchi, Anstee, Quentin Mark, Tiniakos, Dina, Reeves, Helen Louise

“…The prevalence of obesity and non-alcoholic fatty liver disease (NAFLD) associated hepatocellular carcinoma (HCC) is rising, even in the absence of cirrhosis…”
Get full text

Junctional Adhesion Molecule‐A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4 by Chang, Chao‐Hui, Hale, Sarah J, Cox, Charlotte V., Blair, Allison, Kronsteiner, Barbara, Grabowska, Rita, Zhang, Youyi, Cook, David, Khoo, Cheen P., Schrader, Jack B., Kabuga, Suranahi Buglass, Martin‐Rendon, Enca, Watt, Suzanne M.

“…Hematopoietic stem/progenitor cells (HSPCs) reside in specialized bone marrow microenvironmental niches, with vascular elements (endothelial/mesenchymal…”
Get full text

Monitoring of cutaneous manifestations of lithium treatment in mental health inpatients by Cox, Charlotte, George, Manoj

Get full text

Chemicals in European residences – Part I: A review of emissions, concentrations and health effects of volatile organic compounds (VOCs) by Halios, Christos H., Landeg-Cox, Charlotte, Lowther, Scott D., Middleton, Alice, Marczylo, Tim, Dimitroulopoulou, Sani

“…One of the more important classes of potentially toxic indoor air chemicals are the Volatile Organic Compounds (VOCs). However, due to a limited understanding…”
Get full text

Direct binding of antithymocyte globulin to haemopoietic progenitor cells in aplastic anaemia by Flynn, Julie, Cox, Charlotte V, Rizzo, Sian, Foukaneli, Theodora

Get full text

Understanding and treating amotivation in people with psychosis: An experimental study of the role of guided imagery by Cox, Charlotte, Jolley, Suzanne, Johns, Louise

“…Abstract Psychological models propose that the amotivational negative symptoms (ANS) of psychosis are influenced by expectations of future events; both…”
Get full text

Direct binding of antithymoctye globulin to haemopoietic progenitor cells in aplastic anaemia by Flynn, Julie, Cox, Charlotte V., Rizzo, Sian, Foukaneli, Theodora, Rice, Katherine, Murphy, Matthew, Welsh, Jonathan, Rutherford, Theodora R., Gordon‐Smith, Edward C., Gibson, Frances M.

“…Antithymocyte globulin (ATG) is widely used in the treatment of aplastic anaemia (AA) and a response occurs in 60–80% of patients. However, its exact mechanism…”
Get full text