Search Results - "Cowley, W"

Geological setting of exceptional geological features of the Flinders Ranges by Cowley, W. M.

“…The Flinders Ranges in South Australia mainly comprise folded Neoproterozoic to Cambrian sedimentary rocks of the Adelaide Geosyncline, with local inliers of…”
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The genetic dissection of essential hypertension by Cowley, Allen W

“…QTL mapping in humans and rats has identified hundreds of blood-pressure-related phenotypes and genomic regions; the next daunting task is gene identification…”
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A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease by Ilatovskaya, Daria V, Blass, Gregory, Palygin, Oleg, Levchenko, Vladislav, Pavlov, Tengis S, Grzybowski, Michael N, Winsor, Kristen, Shuyskiy, Leonid S, Geurts, Aron M, Cowley, Jr, Allen W, Birnbaumer, Lutz, Staruschenko, Alexander

“…Loss of glomerular podocytes is an indicator of diabetic kidney disease (DKD). The damage to these cells has been attributed in part to elevated intrarenal…”
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Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections by Bukowy, John D, Dayton, Alex, Cloutier, Dustin, Manis, Anna D, Staruschenko, Alexander, Lombard, Julian H, Solberg Woods, Leah C, Beard, Daniel A, Cowley, Jr, Allen W

“…Histologic examination of fixed renal tissue is widely used to assess morphology and the progression of disease. Commonly reported metrics include glomerular…”
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Salt in Health and Disease — A Delicate Balance by Kotchen, Theodore A, Cowley, Allen W, Frohlich, Edward D

“…This review provides an overview of our current understanding of the relation of salt consumption to hypertension and cardiovascular disease. The fact that…”
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The SCUBA-2 Cosmology Legacy Survey: The EGS deep field – II. Morphological transformation and multiwavelength properties of faint submillimetre galaxies by Zavala, J A, Aretxaga, I, Dunlop, J S, Michałowski, M J, Hughes, D H, Bourne, N, Chapin, E, Cowley, W, Farrah, D, Lacey, C, Targett, T, van der Werf, P

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Renal Medullary Oxidative Stress, Pressure-Natriuresis, and Hypertension by Cowley, Allen W

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Robustness of single-cell RNA-seq for identifying differentially expressed genes by Liu, Yong, Huang, Jing, Pandey, Rajan, Liu, Pengyuan, Therani, Bhavika, Qiu, Qiongzi, Rao, Sridhar, Geurts, Aron M, Cowley, Jr, Allen W, Greene, Andrew S, Liang, Mingyu

“…A common feature of single-cell RNA-seq (scRNA-seq) data is that the number of cells in a cell cluster may vary widely, ranging from a few dozen to several…”
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HELP: xid+, the probabilistic de-blender for Herschel SPIRE maps by Hurley, P D, Oliver, S, Betancourt, M, Clarke, C, Cowley, W I, Duivenvoorden, S, Farrah, D, Griffin, M, Lacey, C, Le Floc'h, E, Papadopoulos, A, Sargent, M, Scudder, J M, Vaccari, M, Valtchanov, I, Wang, L

“…We have developed a new prior-based source extraction tool, xid+, to carry out photometry in the Herschel SPIRE (Spectral and Photometric Imaging Receiver)…”
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Progression of diabetic kidney disease in T2DN rats by Palygin, Oleg, Spires, Denisha, Levchenko, Vladislav, Bohovyk, Ruslan, Fedoriuk, Mykhailo, Klemens, Christine A, Sykes, Olga, Bukowy, John D, Cowley, Jr, Allen W, Lazar, Jozef, Ilatovskaya, Daria V, Staruschenko, Alexander

“…Diabetic kidney disease (DKD) is one of the leading pathological causes of decreased renal function and progression to end-stage kidney failure. To explore and…”
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Therapeutic Suppression of mTOR (Mammalian Target of Rapamycin) Signaling Prevents and Reverses Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats by Kumar, Vikash, Evans, Louise C, Kurth, Theresa, Yang, Chun, Wollner, Clayton, Nasci, Victoria, Zheleznova, Nadezhda N, Bukowy, John, Dayton, Alex, Cowley, Allen W

“…mTOR (mammalian target of rapamycin) signaling has emerged as a key regulator in a wide range of cellular processes ranging from cell proliferation, immune…”
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Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats by Kumar, Vikash, Wollner, Clayton, Kurth, Theresa, Bukowy, John D, Cowley, Allen W

“…The goal of the present study was to explore the protective effects of mTORC1 (mammalian target of rapamycin complex 1) inhibition by rapamycin on salt-induced…”
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NOX4/H2O2/mTORC1 Pathway in Salt-Induced Hypertension and Kidney Injury by Kumar, Vikash, Kurth, Theresa, Zheleznova, Nadezhda N., Yang, Chun, Cowley, Allen W.

“…We have reported that a high-salt (4.0% NaCl) dietary intake activates mTORC1 and inhibition of this pathway with rapamycin blunts the chronic phase of…”
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Star Formation in Galaxies at z ∼ 4–5 from the SMUVS Survey: A Clear Starburst/Main-sequence Bimodality for Hα Emitters on the SFR–M Plane by Caputi, K. I., Deshmukh, S., Ashby, M. L. N., Cowley, W. I., Bisigello, L., Fazio, G. G., Fynbo, J. P. U., Fèvre, O. Le, Milvang-Jensen, B., Ilbert, O.

“…Abstract We study a large galaxy sample from the Spitzer Matching Survey of the UltraVISTA ultra-deep Stripes (SMUVS) to search for sources with enhanced 3.6 μ…”
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Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension by Cowley, Jr, Allen W, Abe, Michiaki, Mori, Takefumi, O'Connor, Paul M, Ohsaki, Yusuke, Zheleznova, Nadezhda N

“…The physiological evidence linking the production of superoxide, hydrogen peroxide, and nitric oxide in the renal medullary thick ascending limb of Henle…”
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MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4 by Chuppa, Sandra, Liang, Mingyu, Liu, Pengyuan, Liu, Yong, Casati, Marc C, Cowley, Allen W, Patullo, Leah, Kriegel, Alison J

“…Cardiovascular events are the leading cause of death in patients with chronic kidney disease (CKD), although the pathological mechanisms are poorly understood…”
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Recently released report by The National Academies of Sciences, Engineering, and Medicine proposes significant changes in understanding and managing temporomandibular disorders by Greene, Charles S., Kusiak, John W., Cowley, Terrie, Cowley, Allen W.

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Saturn's magnetic field revealed by the Cassini Grand Finale by Dougherty, Michele K, Cao, Hao, Khurana, Krishan K, Hunt, Gregory J, Provan, Gabrielle, Kellock, Stephen, Burton, Marcia E, Burk, Thomas A, Bunce, Emma J, Cowley, Stanley W H, Kivelson, Margaret G, Russell, Christopher T, Southwood, David J

“…During 2017, the Cassini fluxgate magnetometer made in situ measurements of Saturn's magnetic field at distances ~2550 ± 1290 kilometers above the 1-bar…”
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Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats by Cowley, Jr, Allen W, Yang, Chun, Zheleznova, Nadezhda N, Staruschenko, Alexander, Kurth, Theresa, Rein, Lisa, Kumar, Vikash, Sadovnikov, Katherine, Dayton, Alex, Hoffman, Matthew, Ryan, Robert P, Skelton, Meredith M, Salehpour, Fahimeh, Ranji, Mahsa, Geurts, Aron

“…This study reports the consequences of knocking out NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4) on the development of hypertension and…”
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THE SCUBA-2 COSMOLOGY LEGACY SURVEY: ALMA RESOLVES THE BRIGHT-END OF THE SUB-MILLIMETER NUMBER COUNTS by Simpson, J. M., Smail, Ian, Swinbank, A. M., Chapman, S. C., Geach, J. E., Ivison, R. J., Thomson, A. P., Aretxaga, I., Blain, A. W., Cowley, W. I., Chen, Chian-Chou, Coppin, K. E. K., Dunlop, J. S., Edge, A. C., Farrah, D., Ibar, E., Karim, A., Knudsen, K. K., Meijerink, R., Micha owski, M. J., Scott, D., Spaans, M., P. P. van der Werf

“…ABSTRACT We present high-resolution 870 m Atacama Large Millimeter/sub-millimeter Array (ALMA) continuum maps of 30 bright sub-millimeter sources in the UKIDSS…”
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