Search Results - "Cowley, Diana"

Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin by Drakesmith, Hal, Schimanski, Lisa M., Ormerod, Emma, Merryweather-Clarke, Alison T., Viprakasit, Vip, Edwards, Jon P., Sweetland, Emma, Bastin, Judy M., Cowley, Diana, Chinthammitr, Yingyong, Robson, Kathryn J.H., Townsend, Alain R.M.

“…Ferroportin (FP141414148) mediates iron export from cells; FPN mutations are associated with the iron overloading disorder hemochromatosis. Previously, we…”
Get full text

In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations by Schimanski, Lisa M., Drakesmith, Hal, Merryweather-Clarke, Alison T., Viprakasit, Vip, Edwards, Jon P., Sweetland, Emma, Bastin, Judy M., Cowley, Diana, Chinthammitr, Yingyong, Robson, Kathryn J.H., Townsend, Alain R.M.

“…Type IV hemochromatosis is associated with dominant mutations in the SLC40A1 gene encoding ferroportin (FPN). Known as the “ferroportin disease,” this…”
Get full text

The Hemochromatosis Protein HFE Inhibits Iron Export from Macrophages by Drakesmith, Hal, Sweetland, Emma, Schimanski, Lisa, Edwards, Jon, Cowley, Diana, Ashraf, Mubeen, Bastin, Judy, Alain R. M. Townsend

“…Hereditary hemochromatosis (HH) is a disorder of iron metabolism caused by common mutations in the gene HFE. The HFE protein binds to transferrin receptor-1…”
Get full text

Leslie Clifford Cowley by Cowley, Diana

Get full text

Ferroportin: Lack of evidence for multimers by Schimanski, Lisa M., Drakesmith, Hal, Talbott, Charlotte, Horne, Kerry, James, John R., Davis, Simon J., Sweetland, Emma, Bastin, Judy, Cowley, Diana, Townsend, Alain R.M.

“…Ferroportin is a multi-transmembrane glycoprotein that mediates iron export from cells. Mutations in ferroportin are linked to type IV hemochromatosis, a…”
Get full text