Search Results - "Cowan, Catharine"

Matrix rigidity regulates cancer cell growth and cellular phenotype by Tilghman, Robert W, Cowan, Catharine R, Mih, Justin D, Koryakina, Yulia, Gioeli, Daniel, Slack-Davis, Jill K, Blackman, Brett R, Tschumperlin, Daniel J, Parsons, J Thomas

“…The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent…”
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Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis by Tilghman, Robert W, Blais, Edik M, Cowan, Catharine R, Sherman, Nicholas E, Grigera, Pablo R, Jeffery, Erin D, Fox, Jay W, Blackman, Brett R, Tschumperlin, Daniel J, Papin, Jason A, Parsons, J Thomas

“…Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how…”
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Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice by Dai, Rujuan, Cowan, Catharine, Heid, Bettina, Khan, Deena, Liang, Zhihong, Pham, Christine T N, Ahmed, S Ansar

“…Estrogen, a natural immunomodulator, regulates the development and function of diverse immune cell types. There is now renewed attention on neutrophils and…”
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Commercial rodent diets differentially regulate autoimmune glomerulonephritis, epigenetics and microbiota in MRL/lpr mice by Edwards, Michael R, Dai, Rujuan, Heid, Bettina, Cecere, Thomas E, Khan, Deena, Mu, Qinghui, Cowan, Catharine, Luo, Xin M, Ahmed, S Ansar

“…The course and severity of lupus in spontaneous murine lupus models varies among laboratories, which may be due to variations in diet, housing and/or local…”
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Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib by Walters, Dustin M, Lindberg, James M, Adair, Sara J, Newhook, Timothy E, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Gilmer, Tona M, Parsons, John T, Bauer, Todd W

“…Abstract Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human…”
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What is your diagnosis? Inguinal mass in a dog by Polak, Klaudia Z., Green, Michael L., Cowan, Catharine R., Watson, Allison M., Moore, A Russell

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Low-dose 17α-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice by Edwards, Michael R., Dai, Rujuan, Heid, Bettina, Cowan, Catharine, Werre, Stephen R., Cecere, Thomas, Ahmed, S. Ansar

“…Estrogens have been shown to regulate the immune system and modulate multiple autoimmune diseases. 17α-ethinyl estradiol (EE), a synthetic analog of…”
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Importance of microRNAs and gut microbiota in the characterization of a phenotypic drift in lupus-prone MRL/lpr mice by Puig, Xavier Cabana, Bond, Jacob M., Wang, Zhuang, Dai, Rujuan, Lu, Ran, Lin, Amy, oakes, Vanessa, Rizzo, Amy, Swarwout, Brianna, Abdelhamid, Leila, Mao, Jiangdi, Prakash, Meeta, Sangmeister, Constanza, Cheung, Nathaniel, Cowan, Catharine R, Reilly, Christopher M, Sun, Sha, Ahmed, S Ansar, Luo, Xin M

“…Abstract Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease. The cause of SLE is not only genetic; in fact, environmental factors may play…”
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An Unusual Cause of Femoral Nerve Paresis in a Horse: Disseminated B Cell Lymphoma With Plasmacytoid Differentiation and Direct Neuronal Invasion by Barton, Charlotte K., Hughes, Kelly L., Cowan, Catharine, Nout-Lomas, Yvette S., Nelson, Brad B.

“…•Neurolymphomatosis is a rare cause of lameness and gait dysfunction in horses.•B cell lymphoma with plasmacytoid differentiation is a rare subtype of…”
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Phenotypic and functional characterization of neutrophils from lupus-prone mice (BA4P.223) by Cowan, Catharine, Dai, Rujuan, Heid, Bettina, Ahmed, S.

“…Abstract Neutrophils constitute a critical component of cellular immunity that eliminate infectious organisms through oxidative burst, phagocytosis and the…”
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The effect of dietary phytoestrogen content on the development of systemic lupus erythematosus in the MRL/lpr mouse by Edwards, Michael Richard, Dai, Rujuan, Heid, Bettina, Cowan, Catharine R, Ahmed, S Ansar

“…Abstract Systemic lupus erythematosus is a prototypical autoimmune disease, characterized by the loss of immune cell tolerance to self-antigens, and the…”
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Phenotypic Drift in Lupus-Prone MRL/lpr Mice: Potential Roles of MicroRNAs and Gut Microbiota by Cabana-Puig, Xavier, Bond, Jacob M, Wang, Zhuang, Dai, Rujuan, Lu, Ran, Lin, Amy, Oakes, Vanessa, Rizzo, Amy, Swartwout, Brianna, Abdelhamid, Leila, Mao, Jiangdi, Prakash, Meeta, Sangmeister, Constanza, Cheung, Nathaniel, Cowan, Catharine, Reilly, Christopher M, Sun, Sha, Ahmed, S Ansar, Luo, Xin M

“…MRL/lpr mice have been extensively used as a murine model of lupus. Disease progression in MRL/lpr mice can differ among animal facilities, suggesting a role…”
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Acquired resistance to combination therapy with lapatinib and MEK 1/2 inhibitor GSK1120212 in an in vivo murine model of pancreatic cancer by Lindberg, James M., Walters, Dustin M, Adair, Sara J, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Parsons, J Thomas, Bauer, Todd W.

“…Abstract only 208 Background: Mutations of the oncogene KRAS and activation of cell-surface receptor tyrosine kinases are important and preserved mechanisms of…”
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Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib12 by Walters, Dustin M, Lindberg, James M, Adair, Sara J, Newhook, Timothy E, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Gilmer, Tona M, Parsons, John T, Bauer, Todd W

“…Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human EGFR2…”
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Abstract 1592: Targeting proliferative signals in patient-derived pancreatic cancers propagated orthotopically in immunocompromised mice by Walters, Dustin M., Cowan, Catharine R., Adair, Sara J., Borgman, Cheryl A., Stokes, Jayme B., Stelow, Edward B., Lowrey, Bryce T., Gilmer, Tona M., Parsons, J. Thomas, Bauer, Todd W.

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is associated with the shortest survival duration of any solid cancer. To improve treatment for this disease,…”
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An Unusual Cause of Femoral Nerve Paresis in a Horse: Disseminated B Cell Lymphoma With Plasmacytoid Differentiation and Direct Neuronal Invasion by Barton, Charlotte K, Hughes, Kelly L, Cowan, Catharine, Nout-Lomas, Yvette S, Nelson, Brad B

“…A 21-year-old Quarter Horse mare presented with a chronic, progressively worsening left pelvic limb lameness of 3 weeks duration. The initial examination…”
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CLASSIFICATION BEHAVIOR IN KINDERGARTEN CHILDREN AS A FUNCTION OF RANGE OF TEST STIMULI by COWAN, CATHARINE LOUISE

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