Search Results - "Coven, T R"

Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris by Walters, Ian B., Burack, Lauren H., Coven, Todd R., Gilleaudeau, Patricia, Krueger, James G.

“…Background: Narrow-band UVB (NB-UVB) is a new phototherapy option for psoriasis. Action spectrum studies previously done with different UVB wavelengths suggest…”
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PUVA-induced lymphocyte apoptosis: Mechanism of action in psoriasis by Coven, T. R., Walters, I. B., Cardinale, I., Krueger, J. G.

“…Psoralen plus ultraviolet A (PUVA), utilizing oral 8‐methoxypsoralen (8‐MOP), is a widely utilized and effective treatment for psoriasis vulgaris. Previous…”
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Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B by Coven, T R, Burack, L H, Gilleaudeau, R, Keogh, M, Ozawa, M, Krueger, J G

“…To compare the therapeutic effectiveness of daily exposure to narrowband (NB) UV-B vs broadband (BB) UV-B with and without tar. Half-body exposures to NB UV-B…”
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Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17(TIA-1)+CD8+CD3+ CTLs as determined by phenotypic analysis by Austin, Lisa M., Covens, Todd R., Bhardwaj, Nina, Steinman, Ralph, Krueger, James G.

“…The onset and persistence of psoriatic lesions are linked to the presence of an inflammatory infiltrate of CD3+ lymphocytes that includes CD4+ and CD8+…”
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312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions by Ozawa, M, Ferenczi, K, Kikuchi, T, Cardinale, I, Austin, L M, Coven, T R, Burack, L H, Krueger, J G

“…Narrow-band (312 nm) ultraviolet B light (UVB) is a new form of therapy for psoriasis, but its mechanism of action is unknown. In a bilateral comparison…”
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Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets by Coven, T R, Murphy, F P, Gilleaudeau, P, Cardinale, I, Krueger, J G

“…Psoriasis vulgaris can be effectively treated with trimethylpsoralen (TMP) bath PUVA therapy (psoralen plus UVA), but no data exist on the extent to which…”
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Clinical clearing of psoriasis by 6-thioguanine correlates with cutaneous T-cell depletion via apoptosis: evidence for selective effects on activated T lymphocytes by Murphy, F P, Coven, T R, Burack, L H, Gilleaudeau, P, Cardinale, I, Auerbach, R, Krueger, J G

“…Psoriasis is a common and persistent disease characterized chiefly by marked epidermal and endothelial cell proliferation and inflammation. These changes are…”
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