Search Results - "Covarrubias, Ambart E."
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1
Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway
Published in The Journal of clinical investigation (17-10-2022)“…To understand how kidney donation leads to an increased risk of preeclampsia, we studied pregnant outbred mice with prior uninephrectomy and compared them with…”
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2
Interleukin-6 mediates delirium-like phenotypes in a murine model of urinary tract infection
Published in Journal of neuroinflammation (28-10-2021)“…Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high…”
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3
Double disruption of α2A‐ and α2C ‐adrenoceptors results in sympathetic hyperactivity and high‐bone‐mass phenotype
Published in Journal of bone and mineral research (01-03-2011)“…Evidence demonstrates that sympathetic nervous system (SNS) activation causes osteopenia via β2‐adrenoceptor (β2‐AR) signaling. Here we show that female mice…”
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4
Phagocytosis of Leptospira by leukocytes from mice with different susceptibility to leptospirosis and possible role of chemokines
Published in BMC microbiology (07-01-2019)“…Leptospirosis is a widespread zoonosis caused by pathogenic prokaryotic microbes of the genus Leptospira. Although there are several reports in the literature,…”
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5
AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis
Published in The American journal of pathology (01-01-2019)“…Although the cause of preeclampsia, a pregnancy complication with significant maternal and neonatal morbidity, has not been fully characterized, placental…”
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6
Total Versus Free Placental Growth Factor Levels in the Pathogenesis of Preeclampsia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2020)“…Elevated circulating sFLT-1 (soluble fms-like tyrosine kinase) and low levels of its ligand, PlGF (placental growth factor), are key characteristics of…”
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7
IL-6 Inhibition Reduces Neuronal Injury in a Murine Model of Ventilator-induced Lung Injury
Published in American journal of respiratory cell and molecular biology (01-10-2021)“…Mechanical ventilation is a known risk factor for delirium, a cognitive impairment characterized by dysfunction of the frontal cortex and hippocampus. Although…”
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8
AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts
Published in The American journal of pathology (01-01-2019)“…Although the cause of preeclampsia, a pregnancy complication with significant maternal and neonatal morbidity, has not been fully characterized, placental…”
Get full text
Journal Article -
9
A Three-Dimensional Lung Cell Model to Leptospira Virulence Investigations
Published in Current microbiology (01-02-2022)“…Leptospirosis is a worldwide zoonosis and a serious public health threat in tropical and subtropical areas. The etiologic agents of leptospirosis are…”
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10
The absence of the embryo in the pseudopregnant uterus alters the deposition of some ECM molecules during decidualization in mice
Published in Connective tissue research (01-06-2015)“…The embryo-implantation promotes deep changes in the uterus resulting in the formation of a new structure at the maternal-fetal interface, the decidua…”
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11
Induction of TNF-alfa and CXCL-2 mRNAs in different organs of mice infected with pathogenic Leptospira
Published in Microbial pathogenesis (01-04-2012)“…The role of innate immune response in protection against leptospirosis is poorly understood. We examined the expression of the chemokine CXCL2/MIP-2 and the…”
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12
Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms–like tyrosine kinase 1 pathway
Published in The Journal of clinical investigation (01-10-2022)“…To understand how kidney donation leads to an increased risk of preeclampsia, we studied pregnant outbred mice with prior uninephrectomy and compared them with…”
Get full text
Journal Article -
13
Double disruption of [alpha]2A- and [alpha]2C -adrenoceptors results in sympathetic hyperactivity and high-bone-mass phenotype
Published in Journal of bone and mineral research (01-03-2011)“…Evidence demonstrates that sympathetic nervous system (SNS) activation causes osteopenia via [beta]2-adrenoceptor ([beta]2-AR) signaling. Here we show that…”
Get full text
Journal Article -
14
Double disruption of alpha sub(2A)- and alpha sub(2C) -adrenoceptors results in sympathetic hyperactivity and high-bone-mass phenotype
Published in Journal of bone and mineral research (01-03-2011)“…Evidence demonstrates that sympathetic nervous system (SNS) activation causes osteopenia via beta sub(2)-adrenoceptor ( beta 2-AR) signaling. Here we show that…”
Get full text
Journal Article