Search Results - "Covacci, A"

A Pneumococcal Pilus Influences Virulence and Host Inflammatory Responses by Barocchi, M. A., Ries, J., Zogaj, X., Hemsley, C., Albiger, B., Kanth, A., Dahlberg, S., Fernebro, J., Moschioni, M., Masignani, V., Hultenby, K., Taddei, A. R., Beiter, K., Wartha, F., von Euler, A., Covacci, A., Holden, D. W., Normark, S., Rappuoli, R., Henriques-Normark, B.

“…Streptococcus pneumoniae (pneumococcus) is a major cause of morbidity and mortality world-wide. The initial event in invasive pneumococcal disease is the…”
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Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin by ZHAOYING XIANG, CENSINI, S, BAYELI, P. F, TELFORD, J. L, FIGURA, N, RAPPUOLI, R, COVACCI, A

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THE DESIGN OF VACCINES AGAINST HELICOBACTER PYLORI AND THEIR DEVELOPMENT by Del Giudice, Giuseppe, Covacci, Antonello, Telford, John L, Montecucco, Cesare, Rappuoli, Rino

“…Helicobacter pylori is a gram negative, spiral, microaerophylic bacterium that infects the stomach of more than 50% of the human population worldwide. It is…”
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Induction of Host Signal Transduction Pathways by Helicobacter pylori by Segal, Ellyn D., Lange, C., Covacci, A., Tompkins, L. S., Falkow, S.

“…Adherence of Helicobacter pylori to cultured gastric epithelial cells is associated with several cellular events, including the tyrosine phosphorylation of a…”
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Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer by Covacci, Antonello, Censini, Stefano, Bugnoli, Massimo, Petracca, Roberto, Burroni, Daniela, Macchia, Giovanni, Massone, Annalisa, Papini, Emanuele, Xiang, Zhaoying, Figura, Natale, Rappuoli, Rino

“…Helicobacter pylori has been associated with gastritis, peptic ulcer, and gastric adenocarcinoma. We report the nucleotide sequence and expression of an…”
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Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease by TELFORD, J. L, GHIARA, P, PAPINI, E, MONTECUCCO, C, PARENTE, L, RAPPUOLI, R, DELL'ORCO, M, COMANDUCCI, M, BURRONI, D, BUGNOLI, M, TECCE, M. F, CENSINI, S, COVACCI, A, ZHAOYING XIANG

“…The gram negative, microaerophilic bacterium Helicobacter pylori colonizes the human gastric mucosa and establishes a chronic infection that is tightly…”
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Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype by Crabtree, J E, Covacci, A, Farmery, S M, Xiang, Z, Tompkins, D S, Perry, S, Lindley, I J, Rappuoli, R

“…AIMS--To use a range of natural phenotypically variant strains of Helicobacter pylori with disparate CagA and VacA (vacuolating cytotoxin) expression to…”
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Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori by Crabtree, J E, Xiang, Z, Lindley, I J, Tompkins, D S, Rappuoli, R, Covacci, A

“…The ability of Helicobacter pylori strains to induce interleukin-8 (IL-8) gene expression and protein secretion from gastric epithelial cell lines in vitro is…”
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Biological marker for diseases sustained by Helicobacter pylori infection by Covacci, A.

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Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection by GHIARA, P, ROSSI, M, RAPPUOLI, R, DEL GIUDICE, G, MARCHETTI, M, DI TOMMASO, A, VINDIGNI, C, CIAMPOLINI, F, COVACCI, A, TELFORD, J. L, DE MAGISTRIS, M. T, PIZZA, M

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A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factor-kappa B by Munzenmaier, A, Lange, C, Glocker, E, Covacci, A, Moran, A, Bereswill, S, Baeuerle, PA, Kist, M, Pahl, HL

“…Helicobacter pylori is an etiologic agent in the development of chronic gastritis, duodenal ulceration, and gastric adenocarcinoma. Exposure of gastric…”
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Composition and gene expression of the cag pathogenicity island in Helicobacter pylori strains isolated from gastric carcinoma and gastritis patients in costa rica by OCCHIALINI, Alessandra, MARAIS, Armelle, URDACI, Maria, SIERRA, Rafaela, MUNOZ, Nubia, COVACCI, Antonello, MEGRAUD, Francis

“…The composition and in vitro expression of the cag pathogenicity island genes in a group of Helicobacter pylori strains obtained from patients suffering from…”
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Prevalence of CagA-bearing Helicobacter pylori strains detected by the anti-CagA assay in patients with peptic ulcer disease and in controls by Ching, C K, Wong, B C, Kwok, E, Ong, L, Covacci, A, Lam, S K

“…Cytotoxin-associated gene (CagA)-bearing Helicobacter pylori strains have been associated with significant gastroduodenal pathologies. We have performed a…”
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cagA positive and negative Helicobacter pylori strains are simultaneously present in the stomach of most patients with non-ulcer dyspepsia : relevance to histological damage by FIGURA, N, VINDIGNI, C, KRISTODHULLU, S, GENNARI, C, VAIRA, D, COVACCI, A, PRESENTI, L, BURRONI, D, VERNILLO, R, BANDUCCI, T, ROVIELLO, F, MARRELLI, D, BISCONTRI, M

“…Infection with Helicobacter pylori strains harbouring the cagA gene (cagA+) is associated with an increased risk of developing peptic ulcer and gastric cancer…”
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Cloning, expression, purification, and characterization of Streptococcus pneumoniae IgA1 protease by Romanello, V., Marcacci, M., Molin, F. Dal, Moschioni, M., Censini, S., Covacci, A., Baritussio, A.G., Montecucco, C., Tonello, F.

“…The IgA1 protease of Streptococcus pneumoniae is a Zn-metalloproteinase of 1964 amino acids that specifically cleaves the hinge region of IgA1, the predominant…”
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“Cervia Working Group Report”: Guidelines on the diagnosis and treatment of Helicobacter pylori infection by Caselli, M., Parente, F., Palli, D., Covacci, A., Alvisi, V., Gasbarrini, G., Bianchi Porro, G.

“…Different national attitudes exist between countries in Europe concerning eradication of Helicobacter pylori infection due to the wide differences in…”
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Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) of Helicobacter pylori by XIANG, Z, BUGNOLI, M, RAPPUOLI, R, PONZETTO, A, MORGANDO, A, FIGURA, N, COVACCI, A, PETRACCA, R, PENNATINI, C, CENSINI, S, ARMELLINI, D

“…The possibility of using a recombinant fragment of the CagA (128 kDa protein) for the diagnosis of Helicobacter pylori infection was evaluated. Following…”
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Helicobacter pylori pathogenicity: the bacterium and the host by Covacci, A

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A recombinant fragment of Helicobacter pylori CagA affects proliferation of human cells by Rudnicka, W, Covacci, A, Wadstrom, T, Chmiela, M

“…The outcome of H. pylori infectins depends on proliferation of various host cells, including lymphocytes, monocytes and epithelial cells. In this study we…”
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Tyrosine Phosphorylation of the Helicobacter pylori CagA Antigen after cag-Driven Host Cell Translocation by Stein, Markus, Rappuoli, Rino, Covacci, Antonello

“…Helicobacter pylori strains associated with severe tissue damage and inflammation possess a unique genetic locus, cag, containing 31 genes originating from a…”
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