Search Results - "Coutureau, Etienne"
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1
Dopamine blockade impairs the exploration-exploitation trade-off in rats
Published in Scientific reports (01-05-2019)“…In a volatile environment where rewards are uncertain, successful performance requires a delicate balance between exploitation of the best option and…”
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2
Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat
Published in eLife (06-02-2018)“…Highly distributed neural circuits are thought to support adaptive decision-making in volatile and complex environments. Notably, the functional interactions…”
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3
A thalamocortical circuit for updating action-outcome associations
Published in eLife (23-04-2019)“…The ability to flexibly use knowledge is one cardinal feature of goal-directed behaviors. We recently showed that thalamocortical and corticothalamic pathways…”
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4
Insular and Ventrolateral Orbitofrontal Cortices Differentially Contribute to Goal-Directed Behavior in Rodents
Published in Cerebral cortex (New York, N.Y. 1991) (01-07-2018)“…Abstract The medial prefrontal cortex (mPFC) has long been considered a critical site in action control. However, recent evidence indicates that the…”
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5
Obesogenic diet induces circuit-specific memory deficits in mice
Published in eLife (04-03-2024)“…Obesity is associated with neurocognitive dysfunction, including memory deficits. This is particularly worrisome when obesity occurs during adolescence, a…”
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6
Parallel inputs from the mediodorsal thalamus to the prefrontal cortex in the rat
Published in The European journal of neuroscience (01-08-2016)“…There is a growing interest in determining the functional contribution of thalamic inputs to cortical functions. In the context of adaptive behaviours,…”
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7
Long-lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescence
Published in The European journal of neuroscience (01-03-2016)“…Adolescence is a critical period characterized by major neurobiological changes. Chronic stimulation of the reward system might constitute an important factor…”
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8
Distinct regional patterns in noradrenergic innervation of the rat prefrontal cortex
Published in Journal of chemical neuroanatomy (01-03-2019)“…•Executive functions subserved by the PFC depend on noradrenergic (NA) projections from the locus cœruleus (LC).•We aimed at describing the pattern of…”
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9
Inactivation of the infralimbic prefrontal cortex reinstates goal-directed responding in overtrained rats
Published in Behavioural brain research (30-11-2003)“…Over the course of extended training, instrumental responding in rats shows a transition from goal-dependent performance to goal-independent performance, as…”
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10
Inhibition of noradrenergic signalling in rodent orbitofrontal cortex impairs the updating of goal-directed actions
Published in eLife (20-02-2023)“…In a constantly changing environment, organisms must track the current relationship between actions and their specific consequences and use this information to…”
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11
The mediodorsal thalamus supports adaptive responding based on stimulus-outcome associations
Published in Current research in neurobiology (01-01-2022)“…The ability to engage into flexible behaviors is crucial in dynamic environments. We recently showed that in addition to the well described role of the…”
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12
Manipulating the revision of reward value during the intertrial interval increases sign tracking and dopamine release
Published in PLoS biology (26-09-2018)“…Recent computational models of sign tracking (ST) and goal tracking (GT) have accounted for observations that dopamine (DA) is not necessary for all forms of…”
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13
Mediodorsal but not anterior thalamic nuclei lesions impair acquisition of a conditional discrimination task
Published in Neurobiology of learning and memory (01-11-2015)“…•MD lesions in rats transiently impair acquisition of a conditional discrimination.•ATN lesions are without effect in the same task.•MD may help identify…”
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14
Personality and predisposition to form habit behaviours during instrumental conditioning in horses (Equus caballus)
Published in PloS one (03-02-2017)“…The relationship between personality and learning abilities has become a growing field of interest. Studies have mainly focused on the relationship with…”
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15
Switching Adolescent High-Fat Diet to Adult Control Diet Restores Neurocognitive Alterations
Published in Frontiers in behavioral neuroscience (21-11-2016)“…In addition to metabolic and cardiovascular disorders, obesity is associated with adverse cognitive and emotional outcomes. Its growing prevalence in…”
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16
Flexible Use of Predictive Cues beyond the Orbitofrontal Cortex: Role of the Submedius Thalamic Nucleus
Published in The Journal of neuroscience (23-09-2015)“…The orbitofrontal cortex (OFC) is known to play a crucial role in learning the consequences of specific events. However, the contribution of OFC thalamic…”
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17
Dissociable effects of anterior and mediodorsal thalamic lesions on spatial goal-directed behavior
Published in Brain Structure and Function (01-01-2016)“…Goal-directed behaviors are thought to be supported by a neural circuit encompassing the prefrontal cortex, the dorsomedial striatum, the amygdala, and, as…”
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18
Dimensions of temperament modulate cue-controlled behavior: a study on Pavlovian to instrumental transfer in horses (Equus caballus)
Published in PloS one (14-06-2013)“…Pavlovian to instrumental transfer (PIT) is a central factor in how cues influence animal behavior. PIT refers to the capacity of a Pavlovian cue that predicts…”
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19
A Role for Medial Prefrontal Dopaminergic Innervation in Instrumental Conditioning
Published in The Journal of neuroscience (20-05-2009)“…To investigate the involvement of dopaminergic projections to the prelimbic and infralimbic cortex in the control of goal-directed responses, a first…”
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20
The role of the rat medial prefrontal cortex in adapting to changes in instrumental contingency
Published in PloS one (04-04-2012)“…In order to select actions appropriate to current needs, a subject must identify relationships between actions and events. Control over the environment is…”
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