Search Results - "Coutts, Lisa D."

New Strategies for the Synthesis of Biologically Important Tetrapyrroles. The “B,C + D + A” Approach to Linear Tetrapyrroles by Jacobi, Peter A, Coutts, Lisa D, Guo, Jiasheng, Hauck, Sheila I, Leung, Sam H

“…Linear tetrapyrroles related to phytochrome (1) were prepared in enantiospecific fashion by a new strategy beginning with ring-B,C synthons of type 19…”
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A Stereospecific Synthesis of 24(S)-Hydroxyvitamin D2, a Prodrug for 1α,24(S)-Dihydroxyvitamin D2 by Coutts, Lisa D, Geiss, William B, Gregg, Brian T, Helle, Mark A, King, Chi-Hsin R, Itov, Zinovy, Mateo, Mary E, Meckler, Harold, Zettler, Mark W, Knutson, Joyce C

“…This contribution describes the first stereospecific synthesis of 24(S)-hydroxyvitamin D2 (1), a metabolite of vitamin D2. This metabolite acts as a prodrug…”
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Preparation of 3β-Acetoxy-17a-Oxo-Androst-5-Ene-7,17-Dione, a Biologically Active Impurity Isolated from the Production of 3β-Acetoxyandrost-5-Ene-7,17-Dione by Coutts, Lisa D., DeOrazio, Russell J., Meckler, Harold

“…An impurity isolated during the kilo-lab preparation of 3β-acetoxyandrost-5-ene-7,17-dione was identified as 3β-acetoxy-17a-oxo-androst-5-ene-7,17-dione. This…”
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A Simple and Efficient Synthesis of N-[2-{(4-Propionyloxyphenyl)thio}ethyl]propionamide (DIPCAP), a Tyrosine-Dependent Cytotoxic Agent as a Topical Antimelanoma Therapy by Coutts, Lisa D., Meckler, Harold, Popp, Karl F.

“…The synthesis of N-[2-{(4-propionyloxyphenyl)thio}ethyl]propionamide (DIPCAP), a tyrosine-dependent cytotoxic agent that is currently being evaluated as a…”
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A Stereospecific Synthesis of 24( S )-Hydroxyvitamin D 2 , a Prodrug for 1α,24( S )-Dihydroxyvitamin D 2 by Coutts, Lisa D., Geiss, William B., Gregg, Brian T., Helle, Mark A., King, Chi-Hsin R., Itov, Zinovy, Mateo, Mary E., Meckler, Harold, Zettler, Mark W., Knutson, Joyce C.

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