Search Results - "Coutsouvelis, John"
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Defibrotide for the treatment of sinusoidal obstruction syndrome: evaluation of response to therapy and patient outcomes
Published in Supportive care in cancer (01-03-2018)“…Purpose Defibrotide is an agent used to treat sinusoidal obstruction syndrome (SOS/VOD) in patients undergoing haemopoietic stem cell transplantation. The aim…”
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Isavuconazole as salvage therapy for mucormycosis
Published in Medical mycology case reports (01-03-2016)“…Mucormycosis carries a high mortality rate with few therapeutic options available. We describe a man with pulmonary/splenic mucormycosis complicating…”
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Capecitabine: effective oral fluoropyrimidine chemotherapy
Published in Expert opinion on pharmacotherapy (01-06-2005)“…Fluoropyrimidine chemotherapy, principally with 5-fluorouracil (5-FU), has been a standard of care for a range of solid tumours for many years. Capecitabine, a…”
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A meta-analysis of palifermin efficacy for the management of oral mucositis in patients with solid tumours and haematological malignancy
Published in Critical reviews in oncology/hematology (01-04-2022)“…[Display omitted] •Palifermin has proven efficacy in minimising the severity of oral mucositis.•Palifermin is beneficial in patients with solid tumours and…”
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Medication reuse programs: a narrative review of the literature
Published in International journal for quality in health care (30-04-2024)“…A proportion of returned medications may potentially meet quality standards to be reused safely. In Australia, there is no regulatory guidance available to…”
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A cost comparison of pembrolizumab: Fixed and weight-based dosing
Published in Journal of oncology pharmacy practice (23-05-2024)“…Pembrolizumab, an immune checkpoint inhibitor, indicated to treat multiple cancers, was initially approved in Australia as weight-based dosing at 2 mg/kg every…”
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Haploidentical Donor Transplants with Cytokine Release Syndrome Have Increased Risk of Clinically Significant Early CMV Reactivation Compared with Matched Donor Transplants Receiving Post-Transplant Cyclophosphamide
Published in Blood (02-11-2023)“…Background: Post-transplant cyclophosphamide (PTCy) enables safe haploidentical stem cell transplantation by reducing graft-versus-host-disease (GVHD) but is…”
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Defibrotide for the management of sinusoidal obstruction syndrome in patients who undergo haemopoietic stem cell transplantation
Published in Cancer treatment reviews (01-11-2016)“…Highlights • Defibrotide is a useful agent in the management of sinusoidal obstruction syndrome (SOS). • Most of the published literature describes prophylaxis…”
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Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update
Published in Journal of pharmacy practice and research (01-02-2024)“…Chronic kidney disease (CKD) is a major health concern with a growing disease burden and inequalities in access to treatments. Glomerular filtration rate (GFR)…”
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ANZTCT practice statement: sinusoidal obstruction syndrome/veno‐occlusive disease diagnosis and management
Published in Internal medicine journal (01-09-2024)“…Sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD) is a life‐threatening complication which can develop after haemopoietic stem cell…”
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Asparaginase in the management of adult acute lymphoblastic leukaemia: Is it used appropriately?
Published in Cancer treatment reviews (01-05-2011)“…Abstract Background Whereas the disease free survival (DFS) continues to improve in paediatric acute lymphoblastic leukaemia (ALL), the prognosis of adult ALL…”
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Failure to achieve therapeutic levels with high-dose posaconazole tablets potentially due to enhanced clearance
Published in Journal of oncology pharmacy practice (01-01-2018)“…Aim To describe a case of persistent sub-therapeutic posaconazole levels in setting of salvage chemotherapy for relapsed acute myeloid leukemia. Case details A…”
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Dapsone and azole interactions: A clinical perspective
Published in Journal of oncology pharmacy practice (01-12-2018)“…An understanding of the clinical significance of dapsone-drug interactions is essential for optimal use of this agent. This review aims to provide clinicians…”
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Developing clinical indicators for oncology: the inaugural cancer care indicator set for the Australian Council on Healthcare Standards
Published in Medical journal of Australia (01-06-2021)“…Introduction The Australian Council on Healthcare Standards (ACHS) sponsored an expert‐led, consensus‐driven, four‐stage process, based on a modified Delphi…”
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Improving the transition of highly complex patients into the community: impact of a pharmacist in an allogeneic stem cell transplant (SCT) outpatient clinic
Published in Supportive care in cancer (01-12-2013)“…Purpose Patients having undergone allogeneic stem cell transplantation (SCT) require complex medication regimens. To ensure the safe and effective management…”
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DCEP as a bridge to ongoing therapies for advanced relapsed and/or refractory multiple myeloma
Published in Leukemia & lymphoma (02-12-2018)“…There is limited data describing dexamethasone, cyclophosphamide, etoposide, and cisplatin (DCEP) in relapsed refractory multiple myeloma (RRMM). We reviewed…”
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Implementation of Partnered Pharmacist Medication Charting in haematology and oncology inpatients
Published in Journal of oncology pharmacy practice (01-06-2024)“…Aim Partnered Pharmacist Medication Charting (PPMC) in patients admitted under general medical units has been shown to reduce medication errors. The aim of…”
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Successful autologous stem cell transplant with LACE‐chemotherapy on the background of human immunodeficiency virus
Published in Journal of pharmacy practice and research (01-06-2018)“…Aim To describe a case of autologous stem cell transplantation (ASCT) and successful engraftment in a human immunodeficiency virus (HIV) patient with lymphoma…”
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The impact of pharmacist‐led strategies implemented to reduce errors related to cancer therapies: a systematic review
Published in Journal of pharmacy practice and research (01-12-2020)“…Background Patients with cancer are managed across the whole healthcare spectrum. This complex system of interdependencies has high potential for errors to…”
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