Search Results - "Couto, J R"

Cloning and expression in Escherichia coli of a yeast mannosyltransferase from the asparagine-linked glycosylation pathway by Couto, J R, Huffaker, T C, Robbins, P W

“…The yeast Saccharomyces cerevisiae temperature-sensitive lethal mutant alg1-1, has been previously shown to lack the activity necessary for the addition of the…”
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A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing by Burgess, S, Couto, J R, Guthrie, C

“…We previously described a dominant suppressor of the splicing defect conferred by an A---C intron branchpoint mutation in S. cerevisiae. Suppression occurs by…”
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A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation by Couto, J R, Tamm, J, Parker, R, Guthrie, C

“…Splicing of introns from Saccharomyces cerevisiae pre-mRNA requires the conserved sequence TACTAAC; the 3'-most A residue is utilized as the site of branch…”
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Using VISIR in a large undergraduate course: Preliminary assessment results by Alves, G R, Marques, M A, Viegas, C, Costa Lobo, M C, Barral, R G, Couto, R J, Jacob, F L, Ramos, C A, Vilao, G M, Covita, D S, Alves, J, Guimaraes, P S, Gustavsson, I

“…The use of remote labs in undergraduate courses has been reported in literature several times since the mid 90's. Nevertheless, very few articles present…”
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Genetic and Biochemical Studies of Asparagine-Linked Oligosaccharide Assembly [and Discussion] by Snider, M. D., Huffaker, T. C., Couto, J. R., Robbins, P. W., Feizi, T.

“…The formation of N-glycosidic linkages of eukaryotic glycoproteins involves the assembly of a specific lipid-linked precursor oligosaccharide in the…”
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Anti-BA46 monoclonal antibody Mc3: humanization using a novel positional consensus and in vivo and in vitro characterization by COUTO, J. R, BLANK, E. W, PETERSON, J. A, CERIANI, R. L

“…Mc3 is a murine mAb that is highly effective in treating breast tumors in experimental radioimmunotherapy. Mc3 binds to BA46, a 46-kDa glycoprotein of the…”
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Cloning of cDNAs encoding the variable domains of antibody BrE-3 and construction of a chimeric antibody by Couto, J R, Blank, E W, Peterson, J A, Ceriani, R L

“…BrE-3 is an IgG1,kappa murine monoclonal antibody that binds to human breast epithelial mucin and that has been shown to be promising for imaging and treatment…”
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Humanization of KC4G3, an anti-human carcinoma antibody by Couto, J R, Padlan, E A, Blank, E W, Peterson, J A, Ceriani, R L

“…We have previously constructed a chimeric version of KC4G3, a murine antibody that reacts with several human epithelial cancers and binds to the human breast…”
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Cloning of cDNAs encoding the variable domains of antibody KC4G3 and construction of a chimeric antibody by Couto, J R, Blank, E W, Peterson, J A, Ceriani, R L

“…We have cloned and sequenced cDNAs encoding the variable regions of the light (VL) and heavy (VH) chains of monoclonal antibody KC4G3. VL belongs to group II…”
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Engineering of antibodies for breast cancer therapy: construction of chimeric and humanized versions of the murine monoclonal antibody BrE-3 by Couto, J R, Blank, E W, Peterson, J A, Kiwan, R, Padlan, E A, Ceriani, R L

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Using remote experimentation in a large undergraduate course: Initial findings by Lobo, M. C. C., Alves, G. R., Marques, M. A., Viegas, C., Barral, R. G., Couto, R. J., Jacob, F. L., Ramos, C. A., Vilao, G. M., Covita, D. S., Alves, J., Guimaraes, P. S., Gustavsson, I.

“…The use of remote labs in undergraduate courses has been reported in literature several times since the mid 90's. Nevertheless, very few articles present…”
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Electrocardiogram of the month: 2:1 AV block by Jiménez, O, Couto, J R, Rivera, I

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Efeito residual da adubação potássica do azevém sobre o arroz subseqüente em plantio direto by M. A. Simonete, L. C. Vahl, R. T. Fabres, J. R. R. Couto, R. Lunardi

“…Com o objetivo de avaliar o efeito residual da adubação potássica do azevém sobre o arroz subseqüente, em sistema de semeadura direta, foi desenvolvido um…”
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Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion by Taylor, M R, Couto, J R, Scallan, C D, Ceriani, R L, Peterson, J A

“…Lactadherin, a major glycoprotein of the human milk fat globule membrane, is abundant in human breast milk and expressed in human breast carcinomas…”
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Biodistribution of anti-breast mucin HuBrE3-derived inverted Fabs (IFabs) in nude mice carrying MX-1 xenografts by Speck, R R, Blank, E W, Couto, J R

“…In radioimmunotherapy, the long circulation times of antibody radioconjugates correlate with high relative radiation doses to nontumor tissues. Tumor/normal…”
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Cloning and expression of cDNAs encoding the variable domains of the antibreast carcinoma antibody Mc5 by Christian, R B, Couto, J R, Peterson, J A, Ceriani, R L

“…Mc5, a murine monoclonal antibody that binds to human breast epithelial mucin (BEM), has been shown to be a promising reagent in the diagnosis of breast…”
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Selection of tumor-specific epitopes on target antigens for radioimmunotherapy of breast cancer by Peterson, J A, Couto, J R, Taylor, M R, Ceriani, R L

“…Evidence is presented for two different breast epithelial antigens that some epitopes have greater tumor specificity and are more effective targets for…”
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Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain by Couto, J R, Taylor, M R, Godwin, S G, Ceriani, R L, Peterson, J A

“…The BA46 antigen of the human milk fat globule (HMFG) membrane is expressed in human breast carcinomas and has been used successfully as a target for…”
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Biological activity of two humanized antibodies against two different breast cancer antigens and comparison to their original murine forms by Ceriani, R L, Blank, E W, Couto, J R, Peterson, J A

“…We have humanized two monoclonal antibodies (MoAbs), hu-BrE-3 and hu-Mc3, that are bound to two different antigens of the breast epithelial cell. They bind to…”
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LACTADHERIN, A MEMBRANE-ASSOCIATED ADHESION MOLECULE IN HUMAN MILK.† 381 by Peterson, J A, Couto, J R, Taylor, M R, Scallan, C, Ceriani, R L

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