Search Results - "Couto, Gisele Kruger"
-
1
Renin-angiotensin system overactivation in perivascular adipose tissue contributes to vascular dysfunction in heart failure
Published in Clinical science (1979) (11-12-2020)“…Perivascular adipose tissue (PVAT) dysfunction is associated with vascular damage in cardiometabolic diseases. Although heart failure (HF)-induced endothelial…”
Get more information
Journal Article -
2
Vena cava presents endothelial dysfunction prior to thoracic aorta in heart failure: the pivotal role of nNOS uncoupling/oxidative stress
Published in Clinical science (1979) (10-12-2021)“…Arterial endothelial dysfunction has been extensively studied in heart failure (HF). However, little is known about the adjustments shown by the venous system…”
Get more information
Journal Article -
3
Effects of exercise training on circulating and skeletal muscle renin-angiotensin system in chronic heart failure rats
Published in PloS one (23-05-2014)“…Accumulated evidence shows that the ACE-AngII-AT1 axis of the renin-angiotensin system (RAS) is markedly activated in chronic heart failure (CHF). Recent…”
Get full text
Journal Article -
4
Interaction between advanced glycation end products formation and vascular responses in femoral and coronary arteries from exercised diabetic rats
Published in PloS one (28-12-2012)“…The majority of studies have investigated the effect of exercise training (TR) on vascular responses in diabetic animals (DB), but none evaluated nitric oxide…”
Get full text
Journal Article -
5
-
6
Cyclooxygenase-2 is a critical determinant of angiotensin II-induced vascular remodeling and stiffness in resistance arteries of ouabain-treated rats
Published in Journal of hypertension (01-11-2022)“…Objective: To investigate the role of angiotensin II/AT 1 receptor signaling and/or cyclooxygenase-2 (COX-2) activation on vascular remodeling and stiffening…”
Get full text
Journal Article -
7
Chronic cyclooxygenase-2 inhibition prevents the worsening of hypertension and endothelial dysfunction induced by ouabain in resistance arteries of spontaneously hypertensive rats
Published in Vascular pharmacology (01-08-2021)“…Previous studies raise cyclooxygenase (COX) activation as a possible mechanism involved in the pathophysiology of ouabain-induced hypertension. We hypothesized…”
Get full text
Journal Article -
8
Small artery remodeling and stiffening in deoxycorticosterone acetate-salt hypertensive rats involves the interaction between endogenous ouabain/Na+K+-ATPase/cSrc signaling
Published in Journal of hypertension (01-10-2023)“…Endogenous ouabain (EO) increases in some patients with hypertension and in rats with volume-dependent hypertension. When ouabain binds to Na+K+-ATPase, cSrc…”
Get full text
Journal Article -
9
Sex differences in the participation of endothelial mediators and signaling pathways involved in the vasodilator effect of a selective GPER agonist in resistance arteries of gonadectomized Wistar rats
Published in Life sciences (1973) (01-11-2022)“…Endothelial mechanisms underlying the vascular effects of estrogen modulated by the G protein-coupled estrogen receptor (GPER) are not well understood,…”
Get full text
Journal Article -
10
Renovascular remodeling and renal injury after extended angiotensin II infusion
Published in American journal of physiology. Renal physiology (01-06-2016)“…Chronic angiotensin II (ANG II) infusion for 1 or 2 wk leads to progressive hypertension and induces inward hypertrophic remodeling in preglomerular vessels,…”
Get more information
Journal Article -
11
Protective Effect of Estradiol on Acute Lung Inflammation Induced by an Intestinal Ischemic Insult is Dependent on Nitric Oxide
Published in Shock (Augusta, Ga.) (01-09-2013)“…ABSTRACTIntroductionIt has been shown that the innate immune system mediates acute lung inflammation triggered by intestinal trauma. Sexual dimorphism…”
Get full text
Journal Article -
12
Increment in nNOS and Akt‐eNOS pathway in coronary arteries post‐myocardial infarction can prevent the onset of heart failure
Published in The FASEB journal (01-04-2012)“…Abstract only The imbalance in NO modulation in coronary artery (CA) has been observed in cardiovascular diseases. We tested the hypothesis that NO modulation…”
Get full text
Journal Article -
13
Enhanced Na⁺, K⁺-ATPase activity and endothelial modulation decrease phenylephrine-induced contraction in aorta from ouabain-treated normotensive and hypertensive rats
Published in Hormone molecular biology and clinical investigation (01-05-2014)“…The purpose of this study was to compare the effect of long-term ouabain treatment on the vascular reactivity and Na+, K+-ATPase activity of a conductance…”
Get more information
Journal Article -
14
Dipeptidyl Peptidase IV Inhibition Attenuates Blood Pressure Rising in Young Spontaneously Hypertensive Rats (SHR)
Published in The FASEB journal (01-04-2010)“…The present study aimed to assess the effect of the dipeptidyl peptidase IV inhibitor sitagliptin on renal function and blood pressure in young (5‐wk‐old)…”
Get full text
Journal Article -
15
Protein Disulfide Isomerase expression increases in resistance arteries during hypertension development. Effects on Nox 1 NADPH oxidase signaling
Published in Frontiers in chemistry (01-03-2015)“…NADPH oxidases derived reactive oxygen species (ROS) play an important role in vascular function and remodeling in hypertension through redox signaling…”
Get full text
Journal Article