Search Results - "Cousin, Wendy"
-
1
Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells
Published in Stem cells (Dayton, Ohio) (01-04-2008)“…Human stem cells are powerful tools by which to investigate molecular mechanisms of cell growth and differentiation under normal and pathological conditions…”
Get full text
Journal Article -
2
Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells
Published in Stem cells (Dayton, Ohio) (01-03-2009)“…Mesenchymal stem cells within the bone are responsible for the generation of osteoblasts, chondrocytes, and adipocytes. In rodents, Indian hedgehog has been…”
Get full text
Journal Article -
3
Regenerative capacity of old muscle stem cells declines without significant accumulation of DNA damage
Published in PloS one (21-05-2013)“…The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs…”
Get full text
Journal Article -
4
Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration
Published in Nature communications (10-06-2014)“…The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation;…”
Get full text
Journal Article -
5
Age‐Specific Functional Epigenetic Changes in p21 and p16 in Injury‐Activated Satellite Cells
Published in Stem cells (Dayton, Ohio) (01-03-2015)“…The regenerative capacity of muscle dramatically decreases with age because old muscle stem cells fail to proliferate in response to tissue damage. Here, we…”
Get full text
Journal Article -
6
DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells
Published in The Journal of cell biology (14-10-2013)“…Asymmetry of cell fate is one fundamental property of stem cells, in which one daughter cell self-renews, whereas the other differentiates. Evidence of…”
Get full text
Journal Article -
7
Hedgehog and adipogenesis: Fat and fiction
Published in Biochimie (01-12-2007)“…Morphogenes, abundantly described during embryogenesis have recently emerged as crucial modulators of cell differentiation processes. Hedgehog signaling, the…”
Get full text
Journal Article -
8
Inhibition of the anti-adipogenic Hedgehog signaling pathway by cyclopamine does not trigger adipocyte differentiation
Published in Biochemical and biophysical research communications (20-10-2006)“…Dysregulation of Hedgehog signaling can lead to several pathologies such as congenital defects and cancer. Here, we show that Hedgehog signaling is active in…”
Get full text
Journal Article -
9
Hedgehog and adipogenesis: fat and fiction
Published in Biochimie (01-12-2007)“…Morphogenes, abundantly described during embryogenesis have recently emerged as crucial modulators of cell differentiation processes. Hedgehog signaling, the…”
Get full text
Journal Article -
10
Regenerative Capacity of Old Muscle Stem Cells Declines without Significant Accumulation of DNA Damage. e63528
Published in PloS one (01-05-2013)“…The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs…”
Get full text
Journal Article -
11
Analysis of Ptprv in adipose tissue and adipocyte differentiation
Published in Diabetes (New York, N.Y.) (01-12-2005)“…Ptprv is a transmembrane tyrosine phosphatase expressed in embryonic stem cells, gonads, and osteoblast precursors. In bone formation, it has been…”
Get full text
Journal Article