Search Results - "Courtois, Geneviève"

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia by Dussiot, Michael, Maciel, Thiago T, Fricot, Aurélie, Chartier, Céline, Negre, Olivier, Veiga, Joel, Grapton, Damien, Paubelle, Etienne, Payen, Emmanuel, Beuzard, Yves, Leboulch, Philippe, Ribeil, Jean-Antoine, Arlet, Jean-Benoit, Coté, Francine, Courtois, Geneviève, Ginzburg, Yelena Z, Daniel, Thomas O, Chopra, Rajesh, Sung, Victoria, Hermine, Olivier, Moura, Ivan C

“…Michael Dussiot et al . show that an activin receptor IIA ligand trap ameliorates anemia in a mouse model of β-thalassemia by blocking the deleterious effects…”
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Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1 by Rio, Sarah, Gastou, Marc, Karboul, Narjesse, Derman, Raphaёl, Suriyun, Thunwarat, Manceau, Hana, Leblanc, Thierry, El Benna, Jamel, Schmitt, Caroline, Azouzi, Slim, Larghéro, Jérome, Karim, Zoubida, Macias-Garcia, Alejandra, Chen, Jane-Jane, Hermine, Olivier, Courtois, Geneviève, Puy, Hervé, Gouya, Laurent, Mohandas, Narla, Da Costa, Lydie

“…Diamond-Blackfan anemia (DBA) is a congenital erythroblastopenia that is characterized by a blockade in erythroid differentiation related to impaired ribosome…”
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Ineffective Erythropoiesis in β-Thalassemia by Hermine, Olivier, Courtois, Geneviève, Cruz Moura, Ivan, Dussiot, Michael, Arlet, Jean-Benoit, Ribeil, Jean-Antoine

“…In humans, β-thalassemia dyserythropoiesis is characterized by expansion of early erythroid precursors and erythroid progenitors and then ineffective…”
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XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia by Guillem, Flavia, Dussiot, Michaël, Colin, Elia, Suriyun, Thunwarat, Arlet, Jean Benoit, Goudin, Nicolas, Marcion, Guillaume, Seigneuric, Renaud, Causse, Sebastien, Gonin, Patrick, Gastou, Marc, Deloger, Marc, Rossignol, Julien, Lamarque, Mathilde, Choucair, Zakia Belaid, Gautier, Emilie Fleur, Ducamp, Sarah, Vandekerckhove, Julie, Moura, Ivan C, Maciel, Thiago Trovati, Garrido, Carmen, An, Xiuli, Mayeux, Patrick, Mohandas, Narla, Courtois, Geneviève, Hermine, Olivier

“…β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the…”
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Biallelic mutations in the SARS2 gene presenting as congenital sideroblastic anemia by Colin, Elia, Courtois, Geneviève, Brouzes, Chantal, Pulman, Juliette, Rabant, Marion, Rötig, Agnès, Taffin, Hélène, Lion-Lambert, Mathilde, Fabrega, Sylvie, Da Costa, Lydie, De Montalembert, Mariane, Salomon, Rémi, Hermine, Olivier, Couronné, Lucile

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HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia by Arlet, Jean-Benoît, Ribeil, Jean-Antoine, Guillem, Flavia, Negre, Olivier, Hazoume, Adonis, Marcion, Guillaume, Beuzard, Yves, Dussiot, Michaël, Moura, Ivan Cruz, Demarest, Samuel, de Beauchêne, Isaure Chauvot, Belaid-Choucair, Zakia, Sevin, Margaux, Maciel, Thiago Trovati, Auclair, Christian, Leboulch, Philippe, Chretien, Stany, Tchertanov, Luba, Baudin-Creuza, Véronique, Seigneuric, Renaud, Fontenay, Michaela, Garrido, Carmen, Hermine, Olivier, Courtois, Geneviève

“…In human β-thalassaemiaerythroblasts, HSP70 is sequestered in the cytoplasm by the excess of free α-globin chains and can no longer protect the master…”
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Role of Caspase-10-P13tBID axis in erythropoiesis regulation by Lamarque, Mathilde, Gautier, Emilie-Fleur, Rodrigues, François, Guillem, Flavia, Bayard, Elisa, Broussard, Cédric, Maciel Trovati, Thiago, Arlet, Jean-Benoît, Mayeux, Patrick, Hermine, Olivier, Courtois, Geneviève

“…Red blood cell production is negatively controlled by the rate of apoptosis at the stage of CFU-E/pro-erythroblast differentiation, depending on the balance…”
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Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin by Sibon, David, Coman, Tereza, Rossignol, Julien, Lamarque, Mathilde, Kosmider, Olivier, Bayard, Elisa, Fouquet, Guillemette, Rignault, Rachel, Topçu, Selin, Bonneau, Pierre, Bernex, Florence, Dussiot, Michael, Deroy, Kathy, Laurent, Laetitia, Callebert, Jacques, Launay, Jean-Marie, Georgin-Lavialle, Sophie, Courtois, Geneviève, Maroteaux, Luc, Vaillancourt, Cathy, Fontenay, Michaela, Hermine, Olivier, Côté, Francine

“…Tryptophan as the precursor of several active compounds, including kynurenine and serotonin, is critical for numerous important metabolic functions. Enhanced…”
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A deep dive into future therapies for microcytic anemias and clinical considerations by Rodrigues, François, Coman, Tereza, Fouquet, Guillemette, Côté, Francine, Courtois, Geneviève, Trovati Maciel, Thiago, Hermine, Olivier

“…Microcytic anemias (MA) have frequent or rare etiologies. New discoveries in understanding and treatment of microcytic anemias need to be reviewed. Microcytic…”
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Novel players in β-thalassemia dyserythropoiesis and new therapeutic strategies by Arlet, Jean-Benoît, Dussiot, Michaël, Moura, Ivan C, Hermine, Olivier, Courtois, Geneviève

“…PURPOSE OF REVIEWThe review provides an overview of recent data regarding the molecular players in β-thalassemia dyserythropoiesis and the corresponding…”
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EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro by Forand, Anne, Beck, Laurent, Leroy, Christine, Rousseau, Alice, Boitez, Valérie, Cohen, Isabelle, Courtois, Geneviève, Hermine, Olivier, Friedlander, Gérard

“…The PIT1/SLC20A1 protein, a well-described sodium/phosphate cotransporter and retrovirus receptor, has been identified recently as a modular of proliferation…”
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HSP27 controls GATA-1 protein level during erythroid cell differentiation by de Thonel, Aurelie, Vandekerckhove, Julie, Lanneau, David, Selvakumar, Subramaniam, Courtois, Geneviève, Hazoume, Adonis, Brunet, Mathilde, Maurel, Sebastien, Hammann, Arlette, Ribeil, Jean Antoine, Zermati, Yael, Gabet, Anne Sophie, Boyes, Joan, Solary, Eric, Hermine, Olivier, Garrido, Carmen

“…Heat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting…”
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OTT-MAL Is a Deregulated Activator of Serum Response Factor-Dependent Gene Expression by Descot, Arnaud, Rex-Haffner, Monika, Courtois, Geneviève, Bluteau, Dominique, Menssen, Antje, Mercher, Thomas, Bernard, Olivier A., Treisman, Richard, Posern, Guido

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia by Coulon, Séverine, Dussiot, Michaël, Grapton, Damien, Maciel, Thiago Trovati, Wang, Pamella Huey Mei, Callens, Celine, Tiwari, Meetu Kaushik, Agarwal, Saurabh, Fricot, Aurelie, Vandekerckhove, Julie, Tamouza, Houda, Zermati, Yael, Ribeil, Jean-Antoine, Djedaini, Kamel, Oruc, Zeliha, Pascal, Virginie, Courtois, Geneviève, Arnulf, Bertrand, Alyanakian, Marie-Alexandra, Mayeux, Patrick, Leanderson, Tomas, Benhamou, Marc, Cogné, Michel, Monteiro, Renato C, Hermine, Olivier, Moura, Ivan C

“…Séverine Coulon et al . identify a new mechanism regulating red blood cell production through transferrin receptor engagement. By binding this receptor on…”
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Interaction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2 by Arnaud, Mary, Mzali, Rym, Gesbert, Franck, Crouin, Catherine, Guenzi, Christine, Vermot-Desroches, Claudine, Wijdenes, John, Courtois, Geneviève, Bernard, Olivier, Bertoglio, Jacques

“…Gab2 (Grb2-associated binder-2), a member of the IRS (insulin receptor substrate)/Gab family of adapter proteins, undergoes tyrosine phosphorylation in…”
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HSP70 regulates ineffective erythropoiesis in beta-thalassaemia by Arlet, Jean-Benoît, Ribeil, Jean-Antoine, Guillem, Flavia, Hermine, Olivier, Courtois, Geneviève

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Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes by Frisan, Emilie, Vandekerckhove, Julie, de Thonel, Aurélie, Pierre-Eugène, Cécile, Sternberg, Alexander, Arlet, Jean-Benoît, Floquet, Célia, Gyan, Emmanuel, Kosmider, Olivier, Dreyfus, François, Gabet, Anne-Sophie, Courtois, Geneviève, Vyas, Paresh, Ribeil, Jean-Antoine, Zermati, Yael, Lacombe, Catherine, Mayeux, Patrick, Solary, Eric, Garrido, Carmen, Hermine, Olivier, Fontenay, Michaela

“…Normal human erythroid cell maturation requests the transcription factor GATA-1 and a transient activation of caspase-3, with GATA-1 being protected from…”
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Abstract 3293: Leptin induces breast cancer metastasis through a Neuropilin-1 (NRP-1)/OBR complex by Belaid-Choucair, Zakia, Dam, Julie, Goudin, Nicolas, Filhole, Odile, Cochet, Claude, lepelletier, Yves, Coman, Tereza, Courtois, Geneviève, Colige, Alain, Defresne, Marie-Paule, Jockers, Ralf, Hermine, Olivier

“…Several studies have demonstrated Neuropilin-1 (NRP-1) implication in tumor progression independently of its known co-receptors. On the basis of growing…”
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EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro by Forand, Anne, Beck, Laurent, Leroy, Christine, Rousseau, Alice, Boitez, Valérie, Cohen, Isabelle, Courtois, Geneviève, Hermine, Olivier, Friedlander, Gérard

“…The PIT1/SLC20A1 protein, a well-described sodium/phosphate cotransporter and retrovirus receptor, has been identified recently as a modular of proliferation…”
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HSP70 sequestration by free [alpha]-globin promotes ineffective erythropoiesis in [Beta]-thalassaemia by Arlet, Jean-Benoît, Ribeil, Jean-Antoine, Guillem, Flavia, Negre, Olivier, Hazoume, Adonis, Marcion, Guillaume, Beuzard, Yves, Dussiot, Michaël, Moura, Ivan Cruz, Demarest, Samuel, de Beauchêne, Isaure Chauvot, Belaid-Choucair, Zakia, Sevin, Margaux, Maciel, Thiago Trovati, Auclair, Christian, Leboulch, Philippe, Chretien, Stany, Tchertanov, Luba, Baudin-Creuza, Véronique, Seigneuric, Renaud, Fontenay, Michaela, Garrido, Carmen, Hermine, Olivier, Courtois, Geneviève

“…β-Thalassaemia major (β-TM) is an inherited haemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of haemoglobin, leading to…”
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