Search Results - "Courtney, Paul F."

Hepatic Uptake in the Dog: Comparison of Uptake in Hepatocytes and Human Embryonic Kidney Cells Expressing Dog Organic Anion-Transporting Polypeptide 1B4 by WILBY, Alison J, MAEDA, Kazuya, COURTNEY, Paul F, DEBORI, Yasuyuki, WEBBORN, Peter J. H, KITAMURA, Yoshiaki, KUSUHARA, Hiroyuki, RILEY, Rob J, SUGIYAMA, Yuichi

“…Although the dog is frequently used in pharmacological, pharmacokinetic, and drug safety studies, little is known about canine drug transporters. Dog organic…”
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Human stem cell osteoblastogenesis mediated by novel glycogen synthase kinase 3 inhibitors induces bone formation and a unique bone turnover biomarker profile in rats by Gilmour, Peter S., O'Shea, Patrick J., Fagura, Malbinder, Pilling, James E., Sanganee, Hitesh, Wada, Hiroki, Courtney, Paul F., Kavanagh, Stefan, Hall, Peter A., Escott, K. Jane

“…Wnt activation by inhibiting glycogen synthase kinase 3 (GSK-3) causes bone anabolism in rodents making GSK-3 a potential therapeutic target for osteoporotic…”
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The synthesis of novel matrix metalloproteinase inhibitors employing the Ireland-Claisen rearrangement by PRATT, L. M, BECKETT, R. P, LEWIS, C. N, MANGAN, M, MARTIN, F. M, MILLER, K, NAYEE, P, RICKETTS, M. L, THOMAS, W, TODD, R. S, WHITTAKER, M, BELLAMY, C. L, CORKILL, D. J, COSSINS, J, COURTNEY, P. F, DAVIES, S. J, DAVIDSON, A. H, DRUMMOND, A. H, HELFRICH, K

“…Matrix metalloproteinase inhibitors of general formula (1) were synthesised by a route involving an Ireland-Claisen rearrangement which enables systematic…”
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Basophil Mediator Release in Atopic Dermatitis by Bull, Helen A., Courtney, Paul F., Bunker, Christopher B., Rustin, Malcolm H.A., Pearce, Fred L., Dowd, Pauline M.

“…Basophils have been implicated as a source of histamine and pro-inflammatory eicosanoids in atopic dermatitis. However, mechanisms regulating basophil mediator…”
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The synthesis and biological evaluation of non-peptidic matrix metalloproteinase inhibitors by Martin, Fionna M., Beckett, R.Paul, Bellamy, Claire L., Courtney, Paul F., Davies, Stephen J., Drummond, Alan H., Dodd, Rory, Pratt, Lisa M., Patel, Sanjay R., Ricketts, Michelle L., Todd, Richard S., Tuffnell, Andrew R., Ward, John W.S., Whittaker, Mark

“…Novel sulfonamide matrix metalloproteinase inhibitors of general formula ( 9) were synthesised by a route involving a stereoselective conjugate addition…”
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