Search Results - "Courtney, Natalie L."

Abnormal fatty acid metabolism is a core component of spinal muscular atrophy by Deguise, Marc‐Olivier, Baranello, Giovanni, Mastella, Chiara, Beauvais, Ariane, Michaud, Jean, Leone, Alessandro, De Amicis, Ramona, Battezzati, Alberto, Dunham, Christopher, Selby, Kathryn, Warman Chardon, Jodi, McMillan, Hugh J., Huang, Yu‐Ting, Courtney, Natalie L., Mole, Alannah J., Kubinski, Sabrina, Claus, Peter, Murray, Lyndsay M., Bowerman, Melissa, Gillingwater, Thomas H., Bertoli, Simona, Parson, Simon H., Kothary, Rashmi

“…Objective Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder leading to paralysis and subsequent death in young children. Initially…”
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Temporal and tissue-specific variability of SMN protein levels in mouse models of spinal muscular atrophy by Groen, Ewout J N, Perenthaler, Elena, Courtney, Natalie L, Jordan, Crispin Y, Shorrock, Hannah K, van der Hoorn, Dinja, Huang, Yu-Ting, Murray, Lyndsay M, Viero, Gabriella, Gillingwater, Thomas H

“…Abstract Spinal muscular atrophy (SMA) is a progressive motor neuron disease caused by deleterious variants in SMN1 that lead to a marked decrease in survival…”
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Reduced P53 levels ameliorate neuromuscular junction loss without affecting motor neuron pathology in a mouse model of spinal muscular atrophy by Courtney, Natalie L., Mole, Alannah J., Thomson, Alison K., Murray, Lyndsay M.

“…Spinal Muscular Atrophy (SMA) is a childhood motor neuron disease caused by mutations or deletions within the SMN1 gene. At endstages of disease there is…”
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Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn (2b/-) mouse model of spinal muscular atrophy by Murray, Lyndsay M, Beauvais, Ariane, Gibeault, Sabrina, Courtney, Natalie L, Kothary, Rashmi

“…The term motor neuron disease encompasses a spectrum of disorders in which motor neurons are the lost. Importantly, while some motor neurons are lost early in…”
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Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn2b/- mouse model of spinal muscular atrophy by Murray, Lyndsay M, Beauvais, Ariane, Gibeault, Sabrina, Courtney, Natalie L, Kothary, Rashmi

“…Introduction The term motor neuron disease encompasses a spectrum of disorders in which motor neurons are the lost. Importantly, while some motor neurons are…”
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Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn 2b/- mouse model of spinal muscular atrophy by Murray, Lyndsay M., Beauvais, Ariane, Gibeault, Sabrina, Courtney, Natalie L., Kothary, Rashmi

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